Detalhe da pesquisa
1.
ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1.
Cancer Immunol Immunother
; 72(12): 4145-4159, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37796298
2.
Neutron crystallographic studies reveal hydrogen bond and water-mediated interactions between a carbohydrate-binding module and its bound carbohydrate ligand.
Biochemistry
; 54(42): 6435-8, 2015 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26451738
3.
Bioinspired assemblies of plant cell wall polymers unravel the affinity properties of carbohydrate-binding modules.
Soft Matter
; 11(33): 6586-94, 2015 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26189625
4.
Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH-Π interactions.
Proteins
; 82(12): 3466-75, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25302425
5.
Characterization of the substitution pattern of cellulose derivatives using carbohydrate-binding modules.
BMC Biotechnol
; 14: 113, 2014 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25540113
6.
RUBY® - a tetravalent (2+2) bispecific antibody format with excellent functionality and IgG-like stability, pharmacology and developability properties.
MAbs
; 16(1): 2330113, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38527972
7.
Versatile high resolution oligosaccharide microarrays for plant glycobiology and cell wall research.
J Biol Chem
; 287(47): 39429-38, 2012 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22988248
8.
The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies.
Mol Cancer Ther
; 22(1): 89-101, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36343381
9.
Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules.
Glycobiology
; 22(7): 948-61, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22434778
10.
Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies.
J Immunother Cancer
; 10(11)2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36323431
11.
Affinity maturation generates greatly improved xyloglucan-specific carbohydrate binding modules.
BMC Biotechnol
; 9: 92, 2009 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-19878581
12.
The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation.
J Immunother Cancer
; 7(1): 103, 2019 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975201
13.
The crystal structure of XG-34, an evolved xyloglucan-specific carbohydrate-binding module.
Proteins
; 78(3): 785-9, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19950365
14.
Crystallization, neutron data collection, initial structure refinement and analysis of a xyloglucan heptamer bound to an engineered carbohydrate-binding module from xylanase.
Acta Crystallogr F Struct Biol Commun
; 71(Pt 8): 1072-7, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26249702