Pesquisa | Portal de Pesquisa da BVS

1.

Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.

Tait, Christine M; Chinnaiya, Kavitha; Manning, Elizabeth; Murtaza, Mariyam; Ashton, John-Paul; Furley, Nicholas; Hill, Chris J; Alves, C Henrique; Wijnholds, Jan; Erdmann, Kai S; Furley, Andrew; Rashbass, Penny; Das, Raman M; Storey, Kate G; Placzek, Marysia.

PLoS Biol ; 18(3): e3000470, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-32150534

2.

Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin.

Burke, Ryan M; Dirkx, Ronald A; Quijada, Pearl; Lighthouse, Janet K; Mohan, Amy; O'Brien, Meghann; Wojciechowski, Wojciech; Woeller, Collynn F; Phipps, Richard P; Alexis, Jeffrey D; Ashton, John M; Small, Eric M.

Circ Res ; 128(11): 1663-1678, 2021 05 28.

Artigo em Inglês | MEDLINE | ID: mdl-33825488

3.

The cardioprotective actions of statins in targeting mitochondrial dysfunction associated with myocardial ischaemia-reperfusion injury.

Bland, Abigail R; Payne, Fergus M; Ashton, John C; Jamialahmadi, Tannaz; Sahebkar, Amirhossein.

Pharmacol Res ; 175: 105986, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34800627

4.

Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation.

Schroeder, Griffin M; Dutta, Debapratim; Cavender, Chapin E; Jenkins, Jermaine L; Pritchett, Elizabeth M; Baker, Cameron D; Ashton, John M; Mathews, David H; Wedekind, Joseph E.

Nucleic Acids Res ; 48(14): 8146-8164, 2020 08 20.

Artigo em Inglês | MEDLINE | ID: mdl-32597951

5.

It doesn't hurt to TRY - Experiences of youths participating in a TRYathlon event series.

Caperchione, Cristina M; Stolp, Sean; Fransen, Job; English, Madeleine; Wallace, Lee; Harris, David; Ashton, John F.

Health Promot J Austr ; 33(2): 379-385, 2022 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-34170597

6.

Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.

Hernandez, Giovanny; Mills, Taylor S; Rabe, Jennifer L; Chavez, James S; Kuldanek, Susan; Kirkpatrick, Gregory; Noetzli, Leila; Jubair, Widian K; Zanche, Michelle; Myers, Jason R; Stevens, Brett M; Fleenor, Courtney J; Adane, Biniam; Dinarello, Charles A; Ashton, John; Jordan, Craig T; Di Paola, Jorge; Hagman, James R; Holers, V Michael; Kuhn, Kristine A; Pietras, Eric M.

Haematologica ; 105(3): 585-597, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31101752

7.

A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel Î³-aminobutyric acidergic anticonvulsant.

Jones, Alistair; Barker-Haliski, Melissa; Ilie, Andrei S; Herd, Murray B; Baxendale, Sarah; Holdsworth, Celia J; Ashton, John-Paul; Placzek, Marysia; Jayasekera, Bodiabaduge A P; Cowie, Christopher J A; Lambert, Jeremy J; Trevelyan, Andrew J; White, H Steve; Marson, Anthony G; Cunliffe, Vincent T; Sills, Graeme J; Morgan, Alan.

Epilepsia ; 61(10): 2106-2118, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32797628

8.

A novel in vitro model of primary human pediatric lung epithelial cells.

Wang, Qian; Bhattacharya, Soumyaroop; Mereness, Jared A; Anderson, Christopher; Lillis, Jacquelyn A; Misra, Ravi S; Romas, Stephen; Huyck, Heidie; Howell, Amanda; Bandyopadhyay, Gautam; Donlon, Kathy; Myers, Jason R; Ashton, John; Pryhuber, Gloria S; Mariani, Thomas J.

Pediatr Res ; 87(3): 511-517, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-30776794

9.

Does Crizotinib Auto-Inhibit CYP3A in vivo?

Bland, Abigail R; Shrestha, Nensi; Rosengren, Rhonda J; Ashton, John C.

Pharmacology ; 105(11-12): 715-718, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32460299

10.

Experimental Determination of Cancer Drug Targets with Independent Mechanisms of Resistance.

Bland, Abigail R; Shrestha, Nensi; Berry, Maddie; Wilson, Christabel; Ashton, John C.

Curr Cancer Drug Targets ; 22(2): 97-107, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-34994310

11.

Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse.

Kallenbach, Jacob G; Freeberg, Margaret A T; Abplanalp, David; Alenchery, Rahul G; Ajalik, Raquel E; Muscat, Samantha; Myers, Jacquelyn A; Ashton, John M; Loiselle, Alayna; Buckley, Mark R; van Wijnen, Andre J; Awad, Hani A.

Sci Rep ; 12(1): 3026, 2022 02 22.

Artigo em Inglês | MEDLINE | ID: mdl-35194136

12.

Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms.

Morrell, Craig N; Mix, Doran; Aggarwal, Anu; Bhandari, Rohan; Godwin, Matthew; Owens, Phillip; Lyden, Sean P; Doyle, Adam; Krauel, Krystin; Rondina, Matthew T; Mohan, Amy; Lowenstein, Charles J; Shim, Sharon; Stauffer, Shaun; Josyula, Vara Prasad; Ture, Sara K; Yule, David I; Wagner, Larry E; Ashton, John M; Elbadawi, Ayman; Cameron, Scott J.

J Clin Invest ; 132(9)2022 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-35324479

13.

Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo.

Khazan, Negar; Kim, Kyu Kwang; Hansen, Jeanne N; Singh, Niloy A; Moore, Taylor; Snyder, Cameron W A; Pandita, Ravina; Strawderman, Myla; Fujihara, Michiko; Takamura, Yuta; Jian, Ye; Battaglia, Nicholas; Yano, Naohiro; Teramoto, Yuki; Arnold, Leggy A; Hopson, Russell; Kishor, Keshav; Nayak, Sneha; Ojha, Debasmita; Sharon, Ashoke; Ashton, John M; Wang, Jian; Milano, Michael T; Miyamoto, Hiroshi; Linehan, David C; Gerber, Scott A; Kawar, Nada; Singh, Ajay P; Tabdanov, Erdem D; Dokholyan, Nikolay V; Kakuta, Hiroki; Jurutka, Peter W; Schor, Nina F; Rowswell-Turner, Rachael B; Singh, Rakesh K; Moore, Richard G.

J Med Chem ; 65(8): 6039-6055, 2022 04 28.

Artigo em Inglês | MEDLINE | ID: mdl-35404047

14.

Public mental health and the COVID-19 pandemic.

Ashton, John R.

Ir J Psychol Med ; : 1-4, 2021 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-33583448

15.

ALK-Positive Non-Small Cell Lung Cancer; Potential Combination Drug Treatments.

Nensi, Shrestha; Ashton, John.

Curr Cancer Drug Targets ; 21(9): 737-748, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34325640

16.

Considerations for Whole-Slide Analysis of Murine Xenografts Experiments.

Bland, Abigail R; Ashton, John C.

J Histochem Cytochem ; 69(10): 627-631, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34617806

17.

Contact-force recovery predicts the absence of cardiac perforation during steam pops.

Ganapathy, Anand V; Nazeri, Alireza; Ashton, John; Ganapathy, Krithika S; Safavi-Naeini, Payam; Saeed, Mohammed; Rasekh, Abdi; Razavi, Mehdi.

J Interv Card Electrophysiol ; 61(1): 181-186, 2021 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-32533277

18.

Characterizing Neonatal Heart Maturation, Regeneration, and Scar Resolution Using Spatial Transcriptomics.

Misra, Adwiteeya; Baker, Cameron D; Pritchett, Elizabeth M; Burgos Villar, Kimberly N; Ashton, John M; Small, Eric M.

J Cardiovasc Dev Dis ; 9(1)2021 Dec 21.

Artigo em Inglês | MEDLINE | ID: mdl-35050211

19.

Comparison of In Vivo Tissue Temperature Profile and Lesion Geometry for Radiofrequency Ablation With High Power-Short Duration and Moderate Power-Moderate Duration: Effects of Thermal Latency and Contact Force on Lesion Formation.

Nakagawa, Hiroshi; Ikeda, Atsushi; Sharma, Tushar; Govari, Assaf; Ashton, John; Maffre, Jennifer; Lifshitz, Alexander; Fuimaono, Kristine; Yokoyama, Katsuaki; Wittkampf, Fred H M; Jackman, Warren M.

Circ Arrhythm Electrophysiol ; 14(7): e009899, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34138641

20.

Scaffold-mediated CRISPR-Cas9 delivery system for acute myeloid leukemia therapy.

Ho, Tzu-Chieh; Kim, Hye Sung; Chen, Yumei; Li, Yamin; LaMere, Mark W; Chen, Caroline; Wang, Hui; Gong, Jing; Palumbo, Cal D; Ashton, John M; Kim, Hae-Won; Xu, Qiaobing; Becker, Michael W; Leong, Kam W.

Sci Adv ; 7(21)2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-34138728

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