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Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation.

Singh, Alok K; Wang, Rulin; Lombardo, Kara A; Praharaj, Monali; Bullen, C Korin; Um, Peter; Davis, Stephanie; Komm, Oliver; Illei, Peter B; Ordonez, Alvaro A; Bahr, Melissa; Huang, Joy; Gupta, Anuj; Psoter, Kevin J; Jain, Sanjay K; Bivalacqua, Trinity J; Yegnasubramanian, Srinivasan; Bishai, William R.

bioRxiv ; 2022 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-35313583

High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis.

Ruiz-Bedoya, Camilo A; Mota, Filipa; Tucker, Elizabeth W; Mahmud, Farina J; Reyes-Mantilla, Maria I; Erice, Clara; Bahr, Melissa; Flavahan, Kelly; de Jesus, Patricia; Kim, John; Foss, Catherine A; Peloquin, Charles A; Hammoud, Dima A; Ordonez, Alvaro A; Pardo, Carlos A; Jain, Sanjay K.

J Clin Invest ; 132(6)2022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35085105

¹²⁴I-Iodo-DPA-713 Positron Emission Tomography in a Hamster Model of SARS-CoV-2 Infection.

Ruiz-Bedoya, Camilo A; Mota, Filipa; Ordonez, Alvaro A; Foss, Catherine A; Singh, Alok K; Praharaj, Monali; Mahmud, Farina J; Ghayoor, Ali; Flavahan, Kelly; De Jesus, Patricia; Bahr, Melissa; Dhakal, Santosh; Zhou, Ruifeng; Solis, Clarisse V; Mulka, Kathleen R; Bishai, William R; Pekosz, Andrew; Mankowski, Joseph L; Villano, Jason; Klein, Sabra L; Jain, Sanjay K.

Mol Imaging Biol ; 24(1): 135-143, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34424479

The SARS-CoV-2 spike protein binds and modulates estrogen receptors.

Solis, Oscar; Beccari, Andrea R; Iaconis, Daniela; Talarico, Carmine; Ruiz-Bedoya, Camilo A; Nwachukwu, Jerome C; Cimini, Annamaria; Castelli, Vanessa; Bertini, Riccardo; Montopoli, Monica; Cocetta, Veronica; Borocci, Stefano; Prandi, Ingrid G; Flavahan, Kelly; Bahr, Melissa; Napiorkowski, Anna; Chillemi, Giovanni; Ooka, Masato; Yang, Xiaoping; Zhang, Shiliang; Xia, Menghang; Zheng, Wei; Bonaventura, Jordi; Pomper, Martin G; Hooper, Jody E; Morales, Marisela; Rosenberg, Avi Z; Nettles, Kendall W; Jain, Sanjay K; Allegretti, Marcello; Michaelides, Michael.

bioRxiv ; 2022 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-35665018

Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model.

Dhakal, Santosh; Ruiz-Bedoya, Camilo A; Zhou, Ruifeng; Creisher, Patrick S; Villano, Jason S; Littlefield, Kirsten; Ruelas Castillo, Jennie; Marinho, Paula; Jedlicka, Anne E; Ordonez, Alvaro A; Bahr, Melissa; Majewska, Natalia; Betenbaugh, Michael J; Flavahan, Kelly; Mueller, Alice R L; Looney, Monika M; Quijada, Darla; Mota, Filipa; Beck, Sarah E; Brockhurst, Jacqueline; Braxton, Alicia M; Castell, Natalie; Stover, Mitchel; D'Alessio, Franco R; Metcalf Pate, Kelly A; Karakousis, Petros C; Mankowski, Joseph L; Pekosz, Andrew; Jain, Sanjay K; Klein, Sabra L.

mBio ; 12(4): e0097421, 2021 08 31.

Artigo em Inglês | MEDLINE | ID: mdl-34253053

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Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation.

High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis.

¹²⁴I-Iodo-DPA-713 Positron Emission Tomography in a Hamster Model of SARS-CoV-2 Infection.

The SARS-CoV-2 spike protein binds and modulates estrogen receptors.

Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model.

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Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation.

High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis.

124I-Iodo-DPA-713 Positron Emission Tomography in a Hamster Model of SARS-CoV-2 Infection.

The SARS-CoV-2 spike protein binds and modulates estrogen receptors.

Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model.

¹²⁴I-Iodo-DPA-713 Positron Emission Tomography in a Hamster Model of SARS-CoV-2 Infection.