Pesquisa | Portal de Pesquisa da BVS

1.

Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA.

Simonetti, Francesco R; White, Jennifer A; Tumiotto, Camille; Ritter, Kristen D; Cai, Mian; Gandhi, Rajesh T; Deeks, Steven G; Howell, Bonnie J; Montaner, Luis J; Blankson, Joel N; Martin, Albine; Laird, Gregory M; Siliciano, Robert F; Mellors, John W; Siliciano, Janet D.

Proc Natl Acad Sci U S A ; 117(31): 18692-18700, 2020 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-32690683

2.

The BNT162b2 mRNA Vaccine Elicits Robust Humoral and Cellular Immune Responses in People Living With Human Immunodeficiency Virus (HIV).

Woldemeskel, Bezawit A; Karaba, Andrew H; Garliss, Caroline C; Beck, Evan J; Wang, Kristy H; Laeyendecker, Oliver; Cox, Andrea L; Blankson, Joel N.

Clin Infect Dis ; 74(7): 1268-1270, 2022 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-34293114

3.

Discordant antibody and T cell responses to the SARS-CoV-2 Omicron variant in COVID-19 mRNA vaccine recipient.

Woldemeskel, Bezawit A; Garliss, Caroline C; Aytenfisu, Tihitina Y; Johnston, Trevor S; Cox, Andrea L; Karaba, Andrew H; Blankson, Joel N.

Clin Infect Dis ; 2022 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-35438751

4.

A third dose of SARS-CoV-2 vaccine increases neutralizing antibodies against variants of concern in solid organ transplant recipients.

Karaba, Andrew H; Zhu, Xianming; Liang, Tao; Wang, Kristy H; Rittenhouse, Alex G; Akinde, Olivia; Eby, Yolanda; Ruff, Jessica E; Blankson, Joel N; Abedon, Aura T; Alejo, Jennifer L; Cox, Andrea L; Bailey, Justin R; Thompson, Elizabeth A; Klein, Sabra L; Warren, Daniel S; Garonzik-Wang, Jacqueline M; Boyarsky, Brian J; Sitaras, Ioannis; Pekosz, Andrew; Segev, Dorry L; Tobian, Aaron A R; Werbel, William A.

Am J Transplant ; 22(4): 1253-1260, 2022 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-34951746

5.

People with HIV-1 demonstrate type 1 interferon refractoriness associated with upregulated USP18.

Sugawara, Sho; El-Diwany, Ramy; Cohen, Laura K; Rousseau, Kimberly E; Williams, Christopher Y K; Veenhuis, Rebecca T; Mehta, Shruti H; Blankson, Joel N; Thomas, David L; Cox, Andrea L; Balagopal, Ashwin.

J Virol ; 2021 Mar 03.

Artigo em Inglês | MEDLINE | ID: mdl-33658340

6.

mRNA Vaccine-Elicited SARS-CoV-2-Specific T cells Persist at 6 Months and Recognize the Delta Variant.

Woldemeskel, Bezawit A; Garliss, Caroline C; Blankson, Joel N.

Clin Infect Dis ; 2021 Oct 25.

Artigo em Inglês | MEDLINE | ID: mdl-34694362

7.

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.

Ho, Ya-Chi; Shan, Liang; Hosmane, Nina N; Wang, Jeffrey; Laskey, Sarah B; Rosenbloom, Daniel I S; Lai, Jun; Blankson, Joel N; Siliciano, Janet D; Siliciano, Robert F.

Cell ; 155(3): 540-51, 2013 Oct 24.

Artigo em Inglês | MEDLINE | ID: mdl-24243014

8.

The Esperanza Patient: More Hope for a Sterilizing HIV-1 Cure.

Blankson, Joel N.

Ann Intern Med ; 175(1): 135-136, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34781716

9.

Replacing cART with CAR-T Cells: Using Immunotherapy to Cure HIV.

Beck, Sarah E; Blankson, Joel N.

Mol Ther ; 28(7): 1561-1562, 2020 07 08.

Artigo em Inglês | MEDLINE | ID: mdl-32562615

10.

A quantitative approach for measuring the reservoir of latent HIV-1 proviruses.

Bruner, Katherine M; Wang, Zheng; Simonetti, Francesco R; Bender, Alexandra M; Kwon, Kyungyoon J; Sengupta, Srona; Fray, Emily J; Beg, Subul A; Antar, Annukka A R; Jenike, Katharine M; Bertagnolli, Lynn N; Capoferri, Adam A; Kufera, Joshua T; Timmons, Andrew; Nobles, Christopher; Gregg, John; Wada, Nikolas; Ho, Ya-Chi; Zhang, Hao; Margolick, Joseph B; Blankson, Joel N; Deeks, Steven G; Bushman, Frederic D; Siliciano, Janet D; Laird, Gregory M; Siliciano, Robert F.

Nature ; 566(7742): 120-125, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30700913

11.

CD4+ T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses.

Woldemeskel, Bezawit A; Dykema, Arbor G; Garliss, Caroline C; Cherfils, Saphira; Smith, Kellie N; Blankson, Joel N.

J Clin Invest ; 132(5)2022 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-35061630

12.

SARS-CoV-2 vaccination diversifies the CD4+ spike-reactive T cell repertoire in patients with prior SARS-CoV-2 infection.

Dykema, Arbor G; Zhang, Boyang; Woldemeskel, Bezawit A; Garliss, Caroline C; Rashid, Rufiaat; Westlake, Timothy; Zhang, Li; Zhang, Jiajia; Cheung, Laurene S; Caushi, Justina X; Pardoll, Drew M; Cox, Andrea L; Ji, Hongkai; Smith, Kellie N; Blankson, Joel N.

EBioMedicine ; 80: 104048, 2022 May 06.

Artigo em Inglês | MEDLINE | ID: mdl-35533495

13.

SARS-CoV-2 -specific immune responses in boosted vaccine recipients with breakthrough infections during the Omicron variant surge.

Woldemeskel, Bezawit A; Garliss, Caroline C; Aytenfisu, Tihitina Y; Johnston, Trevor S; Beck, Evan J; Dykema, Arbor G; Frumento, Nicole; Wright, Desiree A; Yang, Andrew H; Damanakis, Alexander I; Laeyendecker, Oliver; Cox, Andrea L; Mostafa, Heba H; Karaba, Andrew H; Blankson, Joel N.

JCI Insight ; 2022 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-35389888

14.

Higher Proinflammatory Cytokines Are Associated With Increased Antibody Titer After a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients.

Karaba, Andrew H; Zhu, Xianming; Benner, Sarah E; Akinde, Olivia; Eby, Yolanda; Wang, Kristy H; Saraf, Sharada; Garonzik-Wang, Jacqueline M; Klein, Sabra L; Bailey, Justin R; Cox, Andrea L; Blankson, Joel N; Durand, Christine M; Segev, Dorry L; Werbel, William A; Tobian, Aaron A R.

Transplantation ; 106(4): 835-841, 2022 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-35085183

15.

Boosting of cross-reactive antibodies to endemic coronaviruses by SARS-CoV-2 infection but not vaccination with stabilized spike.

Crowley, Andrew R; Natarajan, Harini; Hederman, Andrew P; Bobak, Carly A; Weiner, Joshua A; Wieland-Alter, Wendy; Lee, Jiwon; Bloch, Evan M; Tobian, Aaron A R; Redd, Andrew D; Blankson, Joel N; Wolf, Dana; Goetghebuer, Tessa; Marchant, Arnaud; Connor, Ruth I; Wright, Peter F; Ackerman, Margaret E.

Elife ; 112022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35289271

16.

A Fourth Dose of COVID-19 Vaccine Does Not Induce Neutralization of the Omicron Variant Among Solid Organ Transplant Recipients With Suboptimal Vaccine Response.

Karaba, Andrew H; Johnston, Trevor S; Aytenfisu, Tihitina Y; Akinde, Olivia; Eby, Yolanda; Ruff, Jessica E; Abedon, Aura T; Alejo, Jennifer L; Blankson, Joel N; Cox, Andrea L; Bailey, Justin R; Klein, Sabra L; Pekosz, Andrew; Segev, Dorry L; Tobian, Aaron A R; Werbel, William A.

Transplantation ; 2022 04 04.

Artigo em Inglês | MEDLINE | ID: mdl-35417115

17.

Adaptive immune responses in vaccinated patients with symptomatic SARS-CoV-2 Alpha infection.

Park, Han-Sol; Shapiro, Janna R; Sitaras, Ioannis; Woldemeskel, Bezawit A; Garliss, Caroline C; Dziedzic, Amanda; Sachithanandham, Jaiprasath; Jedlicka, Anne E; Caputo, Christopher A; Rousseau, Kimberly E; Thakar, Manjusha; Suwanmanee, San; Hauk, Pricila; Aliyu, Lateef; Majewska, Natalia I; Koley, Sushmita; Patel, Bela; Broderick, Patrick; Mosnaim, Giselle; Heath, Sonya L; Spivak, Emily S; Shenoy, Aarthi; Bloch, Evan M; Gniadek, Thomas J; Shoham, Shmuel; Casadevall, Arturo; Hanley, Daniel; Cox, Andrea L; Laeyendecker, Oliver; Betenbaugh, Michael J; Cramer, Steven M; Mostafa, Heba H; Pekosz, Andrew; Blankson, Joel N; Klein, Sabra L; Tobian, Aaron Ar; Sullivan, David; Gebo, Kelly A.

JCI Insight ; 7(5)2022 03 08.

Artigo em Inglês | MEDLINE | ID: mdl-35104245

18.

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation.

Shan, Liang; Deng, Kai; Shroff, Neeta S; Durand, Christine M; Rabi, S Alireza; Yang, Hung-Chih; Zhang, Hao; Margolick, Joseph B; Blankson, Joel N; Siliciano, Robert F.

Immunity ; 36(3): 491-501, 2012 Mar 23.

Artigo em Inglês | MEDLINE | ID: mdl-22406268

19.

How elite controllers and posttreatment controllers inform our search for an HIV-1 cure.

Li, Jonathan Z; Blankson, Joel N.

J Clin Invest ; 131(11)2021 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-34060478

20.

SARS-CoV-2 mRNA vaccines induce broad CD4+ T cell responses that recognize SARS-CoV-2 variants and HCoV-NL63.