Pesquisa | Portal de Pesquisa da BVS

1.

A processing product of the Plasmodium falciparum reticulocyte binding protein RH1 shows a close association with AMA1 during junction formation.

Gunalan, Karthigayan; Gao, Xiaohong; Yap, Sally Shu Lin; Lai, Soak Kuan; Ravasio, Andrea; Ganesan, Sundar; Li, Hoi Yeung; Preiser, Peter R.

Cell Microbiol ; 22(9): e13232, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32452132

2.

Transcriptome profiling of Plasmodium vivax in Saimiri monkeys identifies potential ligands for invasion.

Gunalan, Karthigayan; Sá, Juliana M; Moraes Barros, Roberto R; Anzick, Sarah L; Caleon, Ramoncito L; Mershon, J Patrick; Kanakabandi, Kishore; Paneru, Monica; Virtaneva, Kimmo; Martens, Craig; Barnwell, John W; Ribeiro, Jose M; Miller, Louis H.

Proc Natl Acad Sci U S A ; 116(14): 7053-7061, 2019 04 02.

Artigo em Inglês | MEDLINE | ID: mdl-30872477

3.

PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection.

Bansal, Abhisheka; Molina-Cruz, Alvaro; Brzostowski, Joseph; Liu, Poching; Luo, Yan; Gunalan, Karthigayan; Li, Yuesheng; Ribeiro, José M C; Miller, Louis H.

Proc Natl Acad Sci U S A ; 115(4): 774-779, 2018 01 23.

Artigo em Inglês | MEDLINE | ID: mdl-29311293

4.

Plasmodium vivax Infections Detected in a Large Number of Febrile Duffy-Negative Africans in Dschang, Cameroon.

Djeunang Dongho, Ghyslaine Bruna; Gunalan, Karthigayan; L'Episcopia, Mariangela; Paganotti, Giacomo Maria; Menegon, Michela; Efeutmecheh Sangong, Rose; Bouting Mayaka, Georges; Fondop, Joseph; Severini, Carlo; Sanou Sobze, Martin; Miller, Louis H; Russo, Gianluca.

Am J Trop Med Hyg ; 104(3): 987-992, 2021 01 12.

Artigo em Inglês | MEDLINE | ID: mdl-33534776

5.

Contrasting epidemiology and genetic variation of Plasmodium vivax infecting Duffy-negative individuals across Africa.

Lo, Eugenia; Russo, Gianluca; Pestana, Kareen; Kepple, Daniel; Abagero, Beka Raya; Dongho, Ghyslaine Bruna Djeunang; Gunalan, Karthigayan; Miller, Louis H; Hamid, Muzamil Mahdi Abdel; Yewhalaw, Delenasaw; Paganotti, Giacomo Maria.

Int J Infect Dis ; 108: 63-71, 2021 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-33991680

6.

A Way Forward for Culturing Plasmodium vivax.

Gunalan, Karthigayan; Rowley, Emma H; Miller, Louis H.

Trends Parasitol ; 36(6): 512-519, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32360314

7.

Antigen Discovery, Bioinformatics and Biological Characterization of Novel Immunodominant Babesia microti Antigens.

Verma, Nitin; Puri, Ankit; Essuman, Edward; Skelton, Richard; Anantharaman, Vivek; Zheng, Hong; White, Siera; Gunalan, Karthigayan; Takeda, Kazuyo; Bajpai, Surabhi; Lepore, Timothy J; Krause, Peter J; Aravind, L; Kumar, Sanjai.

Sci Rep ; 10(1): 9598, 2020 06 12.

Artigo em Inglês | MEDLINE | ID: mdl-32533024

8.

Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes.

Ford, Anthony; Kepple, Daniel; Abagero, Beka Raya; Connors, Jordan; Pearson, Richard; Auburn, Sarah; Getachew, Sisay; Ford, Colby; Gunalan, Karthigayan; Miller, Louis H; Janies, Daniel A; Rayner, Julian C; Yan, Guiyun; Yewhalaw, Delenasaw; Lo, Eugenia.

PLoS Negl Trop Dis ; 14(10): e0008234, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-33044985

9.

Role of Plasmodium vivax Duffy-binding protein 1 in invasion of Duffy-null Africans.

Gunalan, Karthigayan; Lo, Eugenia; Hostetler, Jessica B; Yewhalaw, Delenasaw; Mu, Jianbing; Neafsey, Daniel E; Yan, Guiyun; Miller, Louis H.

Proc Natl Acad Sci U S A ; 113(22): 6271-6, 2016 May 31.

Artigo em Inglês | MEDLINE | ID: mdl-27190089

10.

P. falciparum RH5-Basigin interaction induces changes in the cytoskeleton of the host RBC.

Aniweh, Yaw; Gao, Xiaohong; Hao, Piliang; Meng, Wei; Lai, Soak Kuan; Gunalan, Karthigayan; Chu, Trang T; Sinha, Ameya; Lescar, Julien; Chandramohanadas, Rajesh; Li, Hoi Yeung; Sze, Siu Kwan; Preiser, Peter R.

Cell Microbiol ; 19(9)2017 09.

Artigo em Inglês | MEDLINE | ID: mdl-28409866

11.

PfRH2b specific monoclonal antibodies inhibit merozoite invasion.

Aniweh, Yaw; Gao, Xiaohong; Gunalan, Karthigayan; Preiser, Peter R.

Mol Microbiol ; 102(3): 386-404, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27438226

12.

Small molecule targeting malaria merozoite surface protein-1 (MSP-1) prevents host invasion of divergent plasmodial species.

Chandramohanadas, Rajesh; Russell, Bruce; Liew, Kingsley; Yau, Yin Hoe; Chong, Alvin; Liu, Min; Gunalan, Karthigayan; Raman, Rahul; Renia, Laurent; Nosten, Francois; Shochat, Susana Geifman; Dao, Ming; Sasisekharan, Ram; Suresh, Subra; Preiser, Peter.

J Infect Dis ; 210(10): 1616-26, 2014 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-24864124

13.

The role of the reticulocyte-binding-like protein homologues of Plasmodium in erythrocyte sensing and invasion.

Gunalan, Karthigayan; Gao, Xiaohong; Yap, Sally Shu Lin; Huang, Ximei; Preiser, Peter R.

Cell Microbiol ; 15(1): 35-44, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23046317

14.

Quantitative proteomics reveals new insights into erythrocyte invasion by Plasmodium falciparum.

Kuss, Claudia; Gan, Chee Sian; Gunalan, Karthigayan; Bozdech, Zbynek; Sze, Siu Kwan; Preiser, Peter Rainer.

Mol Cell Proteomics ; 11(2): M111.010645, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22023809

15.

Curcuminoids-loaded liposomes in combination with arteether protects against Plasmodium berghei infection in mice.

Aditya, N P; Chimote, Geetanjali; Gunalan, Karthigayan; Banerjee, Rinti; Patankar, Swati; Madhusudhan, Basavaraj.

Exp Parasitol ; 131(3): 292-9, 2012 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-22561991

16.

Differences in erythrocyte receptor specificity of different parts of the Plasmodium falciparum reticulocyte binding protein homologue 2a.

Gunalan, Karthigayan; Gao, Xiaohong; Liew, Kingsley J L; Preiser, Peter R.

Infect Immun ; 79(8): 3421-30, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21628513

17.

Structural characterization of the erythrocyte binding domain of the reticulocyte binding protein homologue family of Plasmodium yoelii.

Grüber, Ardina; Gunalan, Karthigayan; Ramalingam, Jeya Kumar; Manimekalai, Malathy S S; Grüber, Gerhard; Preiser, Peter R.

Infect Immun ; 79(7): 2880-8, 2011 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-21482683

18.

Frequent expansion of Plasmodium vivax Duffy Binding Protein in Ethiopia and its epidemiological significance.

Lo, Eugenia; Hostetler, Jessica B; Yewhalaw, Delenasaw; Pearson, Richard D; Hamid, Muzamil M A; Gunalan, Karthigayan; Kepple, Daniel; Ford, Anthony; Janies, Daniel A; Rayner, Julian C; Miller, Louis H; Yan, Guiyun.

PLoS Negl Trop Dis ; 13(9): e0007222, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31509523

19.

Plasmodium vivax Infections of Duffy-Negative Erythrocytes: Historically Undetected or a Recent Adaptation?

Gunalan, Karthigayan; Niangaly, Amadou; Thera, Mahamadou A; Doumbo, Ogobara K; Miller, Louis H.

Trends Parasitol ; 34(5): 420-429, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29530446

20.

A Novel Erythrocyte Binding Protein of Plasmodium vivax Suggests an Alternate Invasion Pathway into Duffy-Positive Reticulocytes.

Ntumngia, Francis B; Thomson-Luque, Richard; Torres, Letícia de Menezes; Gunalan, Karthigayan; Carvalho, Luzia H; Adams, John H.

mBio ; 7(4)2016 08 23.

Artigo em Inglês | MEDLINE | ID: mdl-27555313

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