Pesquisa | Portal de Pesquisa da BVS

1.

REALGAR: a web app of integrated respiratory omics data.

Kan, Mengyuan; Diwadkar, Avantika R; Saxena, Supriya; Shuai, Haoyue; Joo, Jaehyun; Himes, Blanca E.

Bioinformatics ; 38(18): 4442-4445, 2022 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-35863045

2.

Genome-wide CRISPR screen identifies suppressors of endoplasmic reticulum stress-induced apoptosis.

Panganiban, Ronald A; Park, Hae-Ryung; Sun, Maoyun; Shumyatcher, Maya; Himes, Blanca E; Lu, Quan.

Proc Natl Acad Sci U S A ; 116(27): 13384-13393, 2019 07 02.

Artigo em Inglês | MEDLINE | ID: mdl-31213543

3.

Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene.

Kan, Mengyuan; Diwadkar, Avantika R; Shuai, Haoyue; Joo, Jaehyun; Wang, Alberta L; Ong, Mei-Sing; Sordillo, Joanne E; Iribarren, Carlos; Lu, Meng X; Hernandez-Pacheco, Natalia; Perez-Garcia, Javier; Gorenjak, Mario; Potocnik, Uros; Burchard, Esteban G; Pino-Yanes, Maria; Wu, Ann Chen; Himes, Blanca E.

J Allergy Clin Immunol ; 149(6): 1981-1991, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-34971648

4.

Inhibition of ABCC1 Decreases cAMP Egress and Promotes Human Airway Smooth Muscle Cell Relaxation.

Cao, Gaoyuan; Lam, Hong; Jude, Joseph A; Karmacharya, Nikhil; Kan, Mengyuan; Jester, William; Koziol-White, Cynthia; Himes, Blanca E; Chupp, Geoffrey L; An, Steven S; Panettieri, Reynold A.

Am J Respir Cell Mol Biol ; 66(1): 96-106, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34648729

5.

Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich's ataxia.

Wang, Dezhen; Ho, Elaine S; Cotticelli, M Grazia; Xu, Peining; Napierala, Jill S; Hauser, Lauren A; Napierala, Marek; Himes, Blanca E; Wilson, Robert B; Lynch, David R; Mesaros, Clementina.

J Lipid Res ; 63(9): 100255, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35850241

6.

Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function.

Goddard, Pagé C; Keys, Kevin L; Mak, Angel C Y; Lee, Eunice Y; Liu, Amy K; Samedy-Bates, Lesly-Anne; Risse-Adams, Oona; Contreras, María G; Elhawary, Jennifer R; Hu, Donglei; Huntsman, Scott; Oh, Sam S; Salazar, Sandra; Eng, Celeste; Himes, Blanca E; White, Marquitta J; Burchard, Esteban G.

Genet Epidemiol ; 45(2): 190-208, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-32989782

7.

Epinephrine evokes shortening of human airway smooth muscle cells following ß₂ adrenergic receptor desensitization.

Deeney, Brian T; Cao, Gaoyuan; Orfanos, Sarah; Lee, Jordan; Kan, Mengyuan; Himes, Blanca E; Parikh, Vishal; Koziol-White, Cynthia J; An, Steven S; Panettieri, Reynold A.

Am J Physiol Lung Cell Mol Physiol ; 323(2): L142-L151, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35787178

8.

CEBPD modulates the airway smooth muscle transcriptomic response to glucocorticoids.

Kan, Mengyuan; Sun, Maoyun; Jiang, Xiaofeng; Diwadkar, Avantika R; Parikh, Vishal; Cao, Gaoyuan; Gebski, Eric; Jester, William; Lan, Bo; Panettieri, Reynold A; Koziol-White, Cynthia; Lu, Quan; Himes, Blanca E.

Respir Res ; 23(1): 193, 2022 Jul 28.

Artigo em Inglês | MEDLINE | ID: mdl-35902923

9.

Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.

Zhu, Zhaozhong; Guo, Yanjun; Shi, Huwenbo; Liu, Cong-Lin; Panganiban, Ronald Allan; Chung, Wonil; O'Connor, Luke J; Himes, Blanca E; Gazal, Steven; Hasegawa, Kohei; Camargo, Carlos A; Qi, Lu; Moffatt, Miriam F; Hu, Frank B; Lu, Quan; Cookson, William O C; Liang, Liming.

J Allergy Clin Immunol ; 145(2): 537-549, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31669095

10.

Airway Smooth Muscle-Specific Transcriptomic Signatures of Glucocorticoid Exposure.

Kan, Mengyuan; Koziol-White, Cynthia; Shumyatcher, Maya; Johnson, Martin; Jester, William; Panettieri, Reynold A; Himes, Blanca E.

Am J Respir Cell Mol Biol ; 61(1): 110-120, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30694689

11.

Whole blood RNA sequencing reveals a unique transcriptomic profile in patients with ARDS following hematopoietic stem cell transplantation.

Englert, Joshua A; Cho, Michael H; Lamb, Andrew E; Shumyatcher, Maya; Barragan-Bradford, Diana; Basil, Maria C; Higuera, Angelica; Isabelle, Colleen; Vera, Mayra Pinilla; Dieffenbach, Paul B; Fredenburgh, Laura E; Kang, Joyce B; Bhatt, Ami S; Antin, Joseph H; Ho, Vincent T; Soiffer, Robert J; Howrylak, Judie A; Himes, Blanca E; Baron, Rebecca M.

Respir Res ; 20(1): 15, 2019 Jan 21.

Artigo em Inglês | MEDLINE | ID: mdl-30665420

12.

Gene Expression Profiles in Children With Suspected Sepsis.

Balamuth, Fran; Alpern, Elizabeth R; Kan, Mengyuan; Shumyatcher, Maya; Hayes, Katie; Lautenbach, Ebbing; Himes, Blanca E.

Ann Emerg Med ; 75(6): 744-754, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-31983492

13.

Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement.

Wu, Ann Chen; Kiley, James P; Noel, Patricia J; Amur, Shashi; Burchard, Esteban G; Clancy, John P; Galanter, Joshua; Inada, Maki; Jones, Tiffanie K; Kropski, Jonathan A; Loyd, James E; Nogee, Lawrence M; Raby, Benjamin A; Rogers, Angela J; Schwartz, David A; Sin, Don D; Spira, Avrum; Weiss, Scott T; Young, Lisa R; Himes, Blanca E.

Am J Respir Crit Care Med ; 198(12): e116-e136, 2018 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-30640517

14.

Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.

Mak, Angel C Y; White, Marquitta J; Eckalbar, Walter L; Szpiech, Zachary A; Oh, Sam S; Pino-Yanes, Maria; Hu, Donglei; Goddard, Pagé; Huntsman, Scott; Galanter, Joshua; Wu, Ann Chen; Himes, Blanca E; Germer, Soren; Vogel, Julia M; Bunting, Karen L; Eng, Celeste; Salazar, Sandra; Keys, Kevin L; Liberto, Jennifer; Nuckton, Thomas J; Nguyen, Thomas A; Torgerson, Dara G; Kwok, Pui-Yan; Levin, Albert M; Celedón, Juan C; Forno, Erick; Hakonarson, Hakon; Sleiman, Patrick M; Dahlin, Amber; Tantisira, Kelan G; Weiss, Scott T; Serebrisky, Denise; Brigino-Buenaventura, Emerita; Farber, Harold J; Meade, Kelley; Lenoir, Michael A; Avila, Pedro C; Sen, Saunak; Thyne, Shannon M; Rodriguez-Cintron, William; Winkler, Cheryl A; Moreno-Estrada, Andrés; Sandoval, Karla; Rodriguez-Santana, Jose R; Kumar, Rajesh; Williams, L Keoki; Ahituv, Nadav; Ziv, Elad; Seibold, Max A; Darnell, Robert B.

Am J Respir Crit Care Med ; 197(12): 1552-1564, 2018 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-29509491

15.

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

Panganiban, Ronald A; Sun, Maoyun; Dahlin, Amber; Park, Hae-Ryung; Kan, Mengyuan; Himes, Blanca E; Mitchel, Jennifer A; Iribarren, Carlos; Jorgenson, Eric; Randell, Scott H; Israel, Elliot; Tantisira, Kelan; Shore, Stephanie; Park, Jin-Ah; Weiss, Scott T; Wu, Ann Chen; Lu, Quan.

J Allergy Clin Immunol ; 142(5): 1469-1478.e2, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-29330013

16.

TGF-ß1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3.

Ojiaku, Christie A; Cao, Gaoyuan; Zhu, Wanqu; Yoo, Edwin J; Shumyatcher, Maya; Himes, Blanca E; An, Steven S; Panettieri, Reynold A.

Am J Respir Cell Mol Biol ; 58(5): 575-584, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-28984468

17.

PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by ß₂-Adrenergic Receptors and Adenylyl Cyclase 6.

Johnstone, Timothy B; Smith, Kaitlyn H; Koziol-White, Cynthia J; Li, Fengying; Kazarian, Austin G; Corpuz, Maia L; Shumyatcher, Maya; Ehlert, Frederick J; Himes, Blanca E; Panettieri, Reynold A; Ostrom, Rennolds S.

Am J Respir Cell Mol Biol ; 58(4): 530-541, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29262264

18.

Inclusion of Unstructured Clinical Text Improves Early Prediction of Death or Prolonged ICU Stay.

Weissman, Gary E; Hubbard, Rebecca A; Ungar, Lyle H; Harhay, Michael O; Greene, Casey S; Himes, Blanca E; Halpern, Scott D.

Crit Care Med ; 46(7): 1125-1132, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29629986

19.

Integrated Stress Response Mediates Epithelial Injury in Mechanical Ventilation.

Dolinay, Tamas; Himes, Blanca E; Shumyatcher, Maya; Lawrence, Gladys Gray; Margulies, Susan S.

Am J Respir Cell Mol Biol ; 57(2): 193-203, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28363030

20.

Using omics approaches to understand pulmonary diseases.

Kan, Mengyuan; Shumyatcher, Maya; Himes, Blanca E.

Respir Res ; 18(1): 149, 2017 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-28774304

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