Pesquisa | Portal de Pesquisa da BVS

1.

HIV-induced neuroinflammation inhibits oligodendrocyte maturation via glutamate-dependent activation of the PERK arm of the integrated stress response.

Roth, Lindsay M; Akay-Espinoza, Cagla; Grinspan, Judith B; Jordan-Sciutto, Kelly L.

Glia ; 69(9): 2252-2271, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34058792

2.

Differential effects of integrase strand transfer inhibitors, elvitegravir and raltegravir, on oligodendrocyte maturation: A role for the integrated stress response.

Roth, Lindsay M; Zidane, Bassam; Festa, Lindsay; Putatunda, Raj; Romer, Micah; Monnerie, Hubert; Jordan-Sciutto, Kelly L; Grinspan, Judith B.

Glia ; 69(2): 362-376, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-32894619

3.

High-content analysis and Kinetic Image Cytometry identify toxicity and epigenetic effects of HIV antiretrovirals on human iPSC-neurons and primary neural precursor cells.

Smith, Alyson S; Ankam, Soneela; Farhy, Chen; Fiengo, Lorenzo; Basa, Ranor C B; Gordon, Kara L; Martin, Charles T; Terskikh, Alexey V; Jordan-Sciutto, Kelly L; Price, Jeffrey H; McDonough, Patrick M.

J Pharmacol Toxicol Methods ; 114: 107157, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35143957

4.

Effects of Antiretroviral Therapy in the Central Nervous System: Beyond Viral Suppression.

Jordan-Sciutto, Kelly L.

J Neuroimmune Pharmacol ; 16(1): 71-73, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33649998

5.

Confound, Cause, or Cure: The Effect of Cannabinoids on HIV-Associated Neurological Sequelae.

Starr, Alexander; Jordan-Sciutto, Kelly L; Mironets, Eugene.

Viruses ; 13(7)2021 06 26.

Artigo em Inglês | MEDLINE | ID: mdl-34206839

6.

Protease Inhibitors, Saquinavir and Darunavir, Inhibit Oligodendrocyte Maturation: Implications for Lysosomal Stress.

Festa, Lindsay; Roth, Lindsay M; K Jensen, Brigid; Geiger, Jonathan D; Jordan-Sciutto, Kelly L; Grinspan, Judith B.

J Neuroimmune Pharmacol ; 16(1): 169-180, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-31776836

7.

Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia.

Ryan, Sean K; Jordan-Sciutto, Kelly L; Anderson, Stewart A.

STAR Protoc ; 1(3): 100190, 2020 12 18.

Artigo em Inglês | MEDLINE | ID: mdl-33377084

8.

The Integrated Stress Response and Phosphorylated Eukaryotic Initiation Factor 2α in Neurodegeneration.

Bond, Sarah; Lopez-Lloreda, Claudia; Gannon, Patrick J; Akay-Espinoza, Cagla; Jordan-Sciutto, Kelly L.

J Neuropathol Exp Neurol ; 79(2): 123-143, 2020 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-31913484

9.

Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection.

Ryan, Sean K; Gonzalez, Michael V; Garifallou, James P; Bennett, Frederick C; Williams, Kimberly S; Sotuyo, Nathaniel P; Mironets, Eugene; Cook, Kieona; Hakonarson, Hakon; Anderson, Stewart A; Jordan-Sciutto, Kelly L.

Stem Cell Reports ; 14(4): 703-716, 2020 04 14.

Artigo em Inglês | MEDLINE | ID: mdl-32220329

10.

BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism.

Stern, Anna L; Ghura, Shivesh; Gannon, Patrick J; Akay-Espinoza, Cagla; Phan, Jessica M; Yee, Alan C; Vassar, Robert; Gelman, Benjamin B; Kolson, Dennis L; Jordan-Sciutto, Kelly L.

J Neurosci ; 38(18): 4288-4300, 2018 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-29632166

11.

Identification and characterization of two novel alternatively spliced E2F1 transcripts in the rat CNS.

Jackson, Dan P; Ting, Jenhao H; Pozniak, Paul D; Meurice, Claire; Schleidt, Stephanie S; Dao, Anh; Lee, Amy H; Klinman, Eva; Jordan-Sciutto, Kelly L.

Mol Cell Neurosci ; 92: 1-11, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-29936143

12.

Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation.

Rom, Slava; Zuluaga-Ramirez, Viviana; Reichenbach, Nancy L; Erickson, Michelle A; Winfield, Malika; Gajghate, Sachin; Christofidou-Solomidou, Melpo; Jordan-Sciutto, Kelly L; Persidsky, Yuri.

J Neuroinflammation ; 15(1): 25, 2018 Jan 27.

Artigo em Inglês | MEDLINE | ID: mdl-29373982

13.

HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via ß-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.

Gannon, Patrick J; Akay-Espinoza, Cagla; Yee, Alan C; Briand, Lisa A; Erickson, Michelle A; Gelman, Benjamin B; Gao, Yan; Haughey, Norman J; Zink, M Christine; Clements, Janice E; Kim, Nicholas S; Van De Walle, Gabriel; Jensen, Brigid K; Vassar, Robert; Pierce, R Christopher; Gill, Alexander J; Kolson, Dennis L; Diehl, J Alan; Mankowski, Joseph L; Jordan-Sciutto, Kelly L.

Am J Pathol ; 187(1): 91-109, 2017 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-27993242

14.

Serum amyloid A: an ozone-induced circulating factor with potentially important functions in the lung-brain axis.

Erickson, Michelle A; Jude, Joseph; Zhao, Hengjiang; Rhea, Elizabeth M; Salameh, Therese S; Jester, William; Pu, Shelley; Harrowitz, Jenna; Nguyen, Ngan; Banks, William A; Panettieri, Reynold A; Jordan-Sciutto, Kelly L.

FASEB J ; 31(9): 3950-3965, 2017 09.

Artigo em Inglês | MEDLINE | ID: mdl-28533327

15.

Reduced sterol regulatory element-binding protein (SREBP) processing through site-1 protease (S1P) inhibition alters oligodendrocyte differentiation in vitro.

Monnerie, Hubert; Romer, Micah; Jensen, Brigid K; Millar, John S; Jordan-Sciutto, Kelly L; Kim, Sangwon F; Grinspan, Judith B.

J Neurochem ; 140(1): 53-67, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27385127

16.

E2F1 in neurons is cleaved by calpain in an NMDA receptor-dependent manner in a model of HIV-induced neurotoxicity.

Zyskind, Jacob W; Wang, Ying; Cho, Giyong; Ting, Jenhao H; Kolson, Dennis L; Lynch, David R; Jordan-Sciutto, Kelly L.

J Neurochem ; 132(6): 742-55, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25279448

17.

Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection.

Ryan, Sean K; Gonzalez, Michael V; Garifallou, James P; Bennett, Frederick C; Williams, Kimberly S; Sotuyo, Nathaniel P; Mironets, Eugene; Cook, Kieona; Hakonarson, Hakon; Anderson, Stewart A; Jordan-Sciutto, Kelly L.

Stem Cell Reports ; 14(5): 991, 2020 05 12.

Artigo em Inglês | MEDLINE | ID: mdl-32402270

18.

Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits.

Ting, Jenhao H; Marks, David R; Schleidt, Stephanie S; Wu, Joanna N; Zyskind, Jacob W; Lindl, Kathryn A; Blendy, Julie A; Pierce, R Christopher; Jordan-Sciutto, Kelly L.

J Neurochem ; 129(5): 850-63, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24460902

19.

Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system.

Akay, Cagla; Cooper, Michael; Odeleye, Akinleye; Jensen, Brigid K; White, Michael G; Vassoler, Fair; Gannon, Patrick J; Mankowski, Joseph; Dorsey, Jamie L; Buch, Alison M; Cross, Stephanie A; Cook, Denise R; Peña, Michelle-Marie; Andersen, Emily S; Christofidou-Solomidou, Melpo; Lindl, Kathryn A; Zink, M Christine; Clements, Janice; Pierce, R Christopher; Kolson, Dennis L; Jordan-Sciutto, Kelly L.

J Neurovirol ; 20(1): 39-53, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24420448

20.

Erratum.

Erickson, Michelle A; Jude, Joseph; Zhao, Hengjiang; Rhea, Elizabeth M; Salameh, Therese S; Jester, William; Pu, Shelley; Harowitz, Jenna; Nguyen, Ngan; Banks, William A; Panettieri, Reynold A; Jordan-Sciutto, Kelly L.

FASEB J ; 32(1): 535, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29295887

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HIV-induced neuroinflammation inhibits oligodendrocyte maturation via glutamate-dependent activation of the PERK arm of the integrated stress response.

Differential effects of integrase strand transfer inhibitors, elvitegravir and raltegravir, on oligodendrocyte maturation: A role for the integrated stress response.

High-content analysis and Kinetic Image Cytometry identify toxicity and epigenetic effects of HIV antiretrovirals on human iPSC-neurons and primary neural precursor cells.

Effects of Antiretroviral Therapy in the Central Nervous System: Beyond Viral Suppression.

Confound, Cause, or Cure: The Effect of Cannabinoids on HIV-Associated Neurological Sequelae.

Protease Inhibitors, Saquinavir and Darunavir, Inhibit Oligodendrocyte Maturation: Implications for Lysosomal Stress.

Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia.

The Integrated Stress Response and Phosphorylated Eukaryotic Initiation Factor 2α in Neurodegeneration.

Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection.

BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism.

Identification and characterization of two novel alternatively spliced E2F1 transcripts in the rat CNS.

Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation.

HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via ß-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.

Serum amyloid A: an ozone-induced circulating factor with potentially important functions in the lung-brain axis.

Reduced sterol regulatory element-binding protein (SREBP) processing through site-1 protease (S1P) inhibition alters oligodendrocyte differentiation in vitro.

E2F1 in neurons is cleaved by calpain in an NMDA receptor-dependent manner in a model of HIV-induced neurotoxicity.

Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection.

Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits.

Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system.

Erratum.