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1.

Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions.

Frost, Adam; Elgort, Marc G; Brandman, Onn; Ives, Clinton; Collins, Sean R; Miller-Vedam, Lakshmi; Weibezahn, Jimena; Hein, Marco Y; Poser, Ina; Mann, Matthias; Hyman, Anthony A; Weissman, Jonathan S.

Cell ; 149(6): 1339-52, 2012 Jun 08.

Artigo em Inglês | MEDLINE | ID: mdl-22682253

2.

Nucleosome-interacting proteins regulated by DNA and histone methylation.

Bartke, Till; Vermeulen, Michiel; Xhemalce, Blerta; Robson, Samuel C; Mann, Matthias; Kouzarides, Tony.

Cell ; 143(3): 470-84, 2010 Oct 29.

Artigo em Inglês | MEDLINE | ID: mdl-21029866

3.

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair.

Sparks, Justin L; Chistol, Gheorghe; Gao, Alan O; Räschle, Markus; Larsen, Nicolai B; Mann, Matthias; Duxin, Julien P; Walter, Johannes C.

Cell ; 176(1-2): 167-181.e21, 2019 01 10.

Artigo em Inglês | MEDLINE | ID: mdl-30595447

4.

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer.

Coscia, Fabian; Lengyel, Ernst; Duraiswamy, Jaikumar; Ashcroft, Bradley; Bassani-Sternberg, Michal; Wierer, Michael; Johnson, Alyssa; Wroblewski, Kristen; Montag, Anthony; Yamada, S Diane; López-Méndez, Blanca; Nilsson, Jakob; Mund, Andreas; Mann, Matthias; Curtis, Marion.

Cell ; 175(1): 159-170.e16, 2018 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-30241606

5.

Dynamics in protein translation sustaining T cell preparedness.

Wolf, Tobias; Jin, Wenjie; Zoppi, Giada; Vogel, Ian A; Akhmedov, Murodzhon; Bleck, Christopher K E; Beltraminelli, Tim; Rieckmann, Jan C; Ramirez, Neftali J; Benevento, Marco; Notarbartolo, Samuele; Bumann, Dirk; Meissner, Felix; Grimbacher, Bodo; Mann, Matthias; Lanzavecchia, Antonio; Sallusto, Federica; Kwee, Ivo; Geiger, Roger.

Nat Immunol ; 21(8): 927-937, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32632289

6.

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

Hubel, Philipp; Urban, Christian; Bergant, Valter; Schneider, William M; Knauer, Barbara; Stukalov, Alexey; Scaturro, Pietro; Mann, Angelika; Brunotte, Linda; Hoffmann, Heinrich H; Schoggins, John W; Schwemmle, Martin; Mann, Matthias; Rice, Charles M; Pichlmair, Andreas.

Nat Immunol ; 20(4): 493-502, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30833792

7.

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

Geiger, Roger; Rieckmann, Jan C; Wolf, Tobias; Basso, Camilla; Feng, Yuehan; Fuhrer, Tobias; Kogadeeva, Maria; Picotti, Paola; Meissner, Felix; Mann, Matthias; Zamboni, Nicola; Sallusto, Federica; Lanzavecchia, Antonio.

Cell ; 167(3): 829-842.e13, 2016 Oct 20.

Artigo em Inglês | MEDLINE | ID: mdl-27745970

8.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein, Marco Y; Hubner, Nina C; Poser, Ina; Cox, Jürgen; Nagaraj, Nagarjuna; Toyoda, Yusuke; Gak, Igor A; Weisswange, Ina; Mansfeld, Jörg; Buchholz, Frank; Hyman, Anthony A; Mann, Matthias.

Cell ; 163(3): 712-23, 2015 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-26496610

9.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Walther, Dirk M; Kasturi, Prasad; Zheng, Min; Pinkert, Stefan; Vecchi, Giulia; Ciryam, Prajwal; Morimoto, Richard I; Dobson, Christopher M; Vendruscolo, Michele; Mann, Matthias; Hartl, F Ulrich.

Cell ; 161(4): 919-32, 2015 May 07.

Artigo em Inglês | MEDLINE | ID: mdl-25957690

10.

Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.

Beli, Petra; Lukashchuk, Natalia; Wagner, Sebastian A; Weinert, Brian T; Olsen, Jesper V; Baskcomb, Linda; Mann, Matthias; Jackson, Stephen P; Choudhary, Chunaram.

Mol Cell ; 46(2): 212-25, 2012 Apr 27.

Artigo em Inglês | MEDLINE | ID: mdl-22424773

11.

Social network architecture of human immune cells unveiled by quantitative proteomics.

Rieckmann, Jan C; Geiger, Roger; Hornburg, Daniel; Wolf, Tobias; Kveler, Ksenya; Jarrossay, David; Sallusto, Federica; Shen-Orr, Shai S; Lanzavecchia, Antonio; Mann, Matthias; Meissner, Felix.

Nat Immunol ; 18(5): 583-593, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28263321

12.

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Bassik, Michael C; Kampmann, Martin; Lebbink, Robert Jan; Wang, Shuyi; Hein, Marco Y; Poser, Ina; Weibezahn, Jimena; Horlbeck, Max A; Chen, Siyuan; Mann, Matthias; Hyman, Anthony A; Leproust, Emily M; McManus, Michael T; Weissman, Jonathan S.

Cell ; 152(4): 909-22, 2013 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-23394947

13.

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.

Gregory, Adam P; Dendrou, Calliope A; Attfield, Kathrine E; Haghikia, Aiden; Xifara, Dionysia K; Butter, Falk; Poschmann, Gereon; Kaur, Gurman; Lambert, Lydia; Leach, Oliver A; Prömel, Simone; Punwani, Divya; Felce, James H; Davis, Simon J; Gold, Ralf; Nielsen, Finn C; Siegel, Richard M; Mann, Matthias; Bell, John I; McVean, Gil; Fugger, Lars.

Nature ; 488(7412): 508-511, 2012 Aug 23.

Artigo em Inglês | MEDLINE | ID: mdl-22801493

14.

Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly.

Qiao, Shuai; Langlois, Christine R; Chrustowicz, Jakub; Sherpa, Dawafuti; Karayel, Ozge; Hansen, Fynn M; Beier, Viola; von Gronau, Susanne; Bollschweiler, Daniel; Schäfer, Tillman; Alpi, Arno F; Mann, Matthias; Prabu, J Rajan; Schulman, Brenda A.

Mol Cell ; 77(1): 150-163.e9, 2020 01 02.

Artigo em Inglês | MEDLINE | ID: mdl-31708416

15.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Walther, Dirk M; Kasturi, Prasad; Zheng, Min; Pinkert, Stefan; Vecchi, Giulia; Ciryam, Prajwal; Morimoto, Richard I; Dobson, Christopher M; Vendruscolo, Michele; Mann, Matthias; Hartl, F Ulrich.

Cell ; 168(5): 944, 2017 02 23.

Artigo em Inglês | MEDLINE | ID: mdl-28235202

16.

Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts.

Larsen, Nicolai B; Gao, Alan O; Sparks, Justin L; Gallina, Irene; Wu, R Alex; Mann, Matthias; Räschle, Markus; Walter, Johannes C; Duxin, Julien P.

Mol Cell ; 73(3): 574-588.e7, 2019 02 07.

Artigo em Inglês | MEDLINE | ID: mdl-30595436

17.

Quantitative, high-resolution proteomics for data-driven systems biology.

Cox, Jürgen; Mann, Matthias.

Annu Rev Biochem ; 80: 273-99, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21548781

18.

The growing landscape of lysine acetylation links metabolism and cell signalling.

Choudhary, Chunaram; Weinert, Brian T; Nishida, Yuya; Verdin, Eric; Mann, Matthias.

Nat Rev Mol Cell Biol ; 15(8): 536-50, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-25053359

19.

The proteome landscape of the kingdoms of life.

Müller, Johannes B; Geyer, Philipp E; Colaço, Ana R; Treit, Peter V; Strauss, Maximilian T; Oroshi, Mario; Doll, Sophia; Virreira Winter, Sebastian; Bader, Jakob M; Köhler, Niklas; Theis, Fabian; Santos, Alberto; Mann, Matthias.

Nature ; 582(7813): 592-596, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32555458

20.

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.

Jayavelu, Ashok Kumar; Schnöder, Tina M; Perner, Florian; Herzog, Carolin; Meiler, Arno; Krishnamoorthy, Gurumoorthy; Huber, Nicolas; Mohr, Juliane; Edelmann-Stephan, Bärbel; Austin, Rebecca; Brandt, Sabine; Palandri, Francesca; Schröder, Nicolas; Isermann, Berend; Edlich, Frank; Sinha, Amit U; Ungelenk, Martin; Hübner, Christian A; Zeiser, Robert; Rahmig, Susann; Waskow, Claudia; Coldham, Iain; Ernst, Thomas; Hochhaus, Andreas; Jilg, Stefanie; Jost, Philipp J; Mullally, Ann; Bullinger, Lars; Mertens, Peter R; Lane, Steven W; Mann, Matthias; Heidel, Florian H.

Nature ; 588(7836): 157-163, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33239784

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Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions.

Nucleosome-interacting proteins regulated by DNA and histone methylation.

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair.

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer.

Dynamics in protein translation sustaining T cell preparedness.

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.

Social network architecture of human immune cells unveiled by quantitative proteomics.

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.

Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts.

Quantitative, high-resolution proteomics for data-driven systems biology.

The growing landscape of lysine acetylation links metabolism and cell signalling.

The proteome landscape of the kingdoms of life.

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.