Pesquisa | Portal de Pesquisa da BVS

1.

A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation.

Liu, Zhijun; Nailwal, Himani; Rector, Jonah; Rahman, Masmudur M; Sam, Richard; McFadden, Grant; Chan, Francis Ka-Ming.

Immunity ; 54(2): 247-258.e7, 2021 02 09.

Artigo em Inglês | MEDLINE | ID: mdl-33444549

2.

RNA Helicase A/DHX9 Forms Unique Cytoplasmic Antiviral Granules That Restrict Oncolytic Myxoma Virus Replication in Human Cancer Cells.

Rahman, Masmudur M; Gutierrez-Jensen, Ami D; Glenn, Honor L; Abrantes, Mario; Moussatche, Nissin; McFadden, Grant.

J Virol ; 95(14): e0015121, 2021 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-33952639

3.

Oncolytic Myxoma virus infects and damages the tegument of the human parasitic flatworm Schistosoma mansoni.

Rahman, Masmudur M; McFadden, Grant; Ruthel, Gordon; Herbert, De'Broski R; Freedman, Bruce D; Greenberg, Robert M; Bais, Swarna.

Exp Parasitol ; 239: 108263, 2022 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-35598646

4.

Myxoma virus M013 protein antagonizes NF-κB and inflammasome pathways via distinct structural motifs.

Garg, Rekha R; Jackson, Cody B; Rahman, Masmudur M; Khan, Amir R; Lewin, Alfred S; McFadden, Grant.

J Biol Chem ; 294(21): 8480-8489, 2019 05 24.

Artigo em Inglês | MEDLINE | ID: mdl-30940649

5.

Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates.

Peng, Chen; Haller, Sherry L; Rahman, Masmudur M; McFadden, Grant; Rothenburg, Stefan.

Proc Natl Acad Sci U S A ; 113(14): 3855-60, 2016 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-26903626

6.

Crystal Structure of Cleaved Serp-1, a Myxomavirus-Derived Immune Modulating Serpin: Structural Design of Serpin Reactive Center Loop Peptides with Improved Therapeutic Function.

Mahon, Brian P; Ambadapadi, Sriram; Yaron, Jordan R; Lomelino, Carrie L; Pinard, Melissa A; Keinan, Shahar; Kurnikov, Igor; Macaulay, Colin; Zhang, Liqiang; Reeves, Westley; McFadden, Grant; Tibbetts, Scott; McKenna, Robert; Lucas, Alexandra R.

Biochemistry ; 57(7): 1096-1107, 2018 02 20.

Artigo em Inglês | MEDLINE | ID: mdl-29227673

7.

Myxoma virus suppresses proliferation of activated T lymphocytes yet permits oncolytic virus transfer to cancer cells.

Villa, Nancy Y; Wasserfall, Clive H; Meacham, Amy M; Wise, Elizabeth; Chan, Winnie; Wingard, John R; McFadden, Grant; Cogle, Christopher R.

Blood ; 125(24): 3778-88, 2015 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-25904246

8.

SAMD9 is an innate antiviral host factor with stress response properties that can be antagonized by poxviruses.

Liu, Jia; McFadden, Grant.

J Virol ; 89(3): 1925-31, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25428864

9.

Ex vivo virotherapy with myxoma virus does not impair hematopoietic stem and progenitor cells.

Villa, Nancy Y; Bais, Swarna; Chan, Winnie M; Meacham, Amy M; Wise, Elizabeth; Rahman, Masmudur M; Moreb, Jan S; Rosenau, Emma H; Wingard, John R; McFadden, Grant; Cogle, Christopher R.

Cytotherapy ; 18(3): 465-80, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26857235

10.

Vaccinia virus dissemination requires p21-activated kinase 1.

Andrade, Luciana G; Albarnaz, Jonas D; Mügge, Fernanda L B; David, Bruna A; Abrahão, Jônatas S; da Fonseca, Flávio G; Kroon, Erna G; Menezes, Gustavo B; McFadden, Grant; Bonjardim, Cláudio A.

Arch Virol ; 161(11): 2991-3002, 2016 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-27465567

11.

Prevention of EBV lymphoma development by oncolytic myxoma virus in a murine xenograft model of post-transplant lymphoproliferative disease.

Kim, Manbok; Rahman, Masmudur M; Cogle, Christopher R; McFadden, Grant.

Biochem Biophys Res Commun ; 462(4): 283-7, 2015 Jul 10.

Artigo em Inglês | MEDLINE | ID: mdl-25843801

12.

Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replication.

Rahman, Masmudur M; Liu, Jia; Chan, Winnie M; Rothenburg, Stefan; McFadden, Grant.

PLoS Pathog ; 9(7): e1003465, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23853588

13.

Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro and further improved by hyaluronan in vivo.

Weng, Mingzhe; Gong, Wei; Ma, Mingzhe; Chu, Bingfeng; Qin, Yiyu; Zhang, Mingdi; Lun, Xueqing; McFadden, Grant; Forsyth, Peter; Yang, Yong; Quan, Zhiwei.

Mol Cancer ; 13: 82, 2014 Apr 13.

Artigo em Inglês | MEDLINE | ID: mdl-24725816

14.

Suppression of collagen-induced arthritis with a serine proteinase inhibitor (serpin) derived from myxoma virus.

Brahn, Ernest; Lee, Sarah; Lucas, Alexandra; McFadden, Grant; Macaulay, Colin.

Clin Immunol ; 153(2): 254-63, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24845791

15.

Evolution of viral sensing RIG-I-like receptor genes in Leporidae genera Oryctolagus, Sylvilagus, and Lepus.

Lemos de Matos, Ana; McFadden, Grant; Esteves, Pedro J.

Immunogenetics ; 66(1): 43-52, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24220721

16.

Myxoma and vaccinia viruses bind differentially to human leukocytes.

Chan, Winnie M; Bartee, Eric C; Moreb, Jan S; Dower, Ken; Connor, John H; McFadden, Grant.

J Virol ; 87(8): 4445-60, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23388707

17.

The tanapoxvirus 15L protein is a virus-encoded neuregulin that promotes viral replication in human endothelial cells.

Jeng, David; Ma, Zhenzhong; Barrett, John W; McFadden, Grant; Loeb, Jeffrey A; Essani, Karim.

J Virol ; 87(6): 3018-26, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23269801

18.

Smallpox: anything to declare?

Smith, Geoffrey L; McFadden, Grant.

Nat Rev Immunol ; 2(7): 521-7, 2002 07.

Artigo em Inglês | MEDLINE | ID: mdl-12094226

19.

Evolution and divergence of the mammalian SAMD9/SAMD9L gene family.

Lemos de Matos, Ana; Liu, Jia; McFadden, Grant; Esteves, Pedro J.

BMC Evol Biol ; 13: 121, 2013 Jun 12.

Artigo em Inglês | MEDLINE | ID: mdl-23758988

20.

Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection.

Chen, Hao; Zheng, Donghang; Abbott, Jeff; Liu, Liying; Bartee, Mee Y; Long, Maureen; Davids, Jennifer; Williams, Jennifer; Feldmann, Heinz; Strong, James; Grau, Katrina R; Tibbetts, Scott; Macaulay, Colin; McFadden, Grant; Thoburn, Robert; Lomas, David A; Spinale, Francis G; Virgin, Herbert W; Lucas, Alexandra.

Antimicrob Agents Chemother ; 57(9): 4114-27, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-23774438

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