Pesquisa | Portal de Pesquisa da BVS

1.

Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice.

El Kasmi, Karim C; Ghosh, Swati; Anderson, Aimee L; Devereaux, Michael W; Balasubramaniyan, Natarajan; D'Alessandro, Angelo; Orlicky, David J; Suchy, Frederick J; Shearn, Colin T; Sokol, Ronald J.

Hepatology ; 75(2): 252-265, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34387888

2.

Chemopreventive Efficacy of Silibinin against Basal Cell Carcinoma Growth and Progression in UVB-irradiated Ptch +/- mice.

Paudel, Sandeep; Raina, Komal; Tiku, Vasundhara R; Maurya, Akhilendra; Orlicky, David J; You, Zhiying; Rigby, Cindy M; Deep, Gagan; Kant, Rama; Raina, Bupinder; Agarwal, Chapla; Agarwal, Rajesh.

Carcinogenesis ; 2022 Feb 20.

Artigo em Inglês | MEDLINE | ID: mdl-35184170

3.

miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis.

Balasubramaniyan, Natarajan; Devereaux, Michael W; Orlicky, David J; Sokol, Ronald J; Suchy, Frederick J.

J Biol Chem ; 297(6): 101400, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34774795

4.

NF-κB Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis.

Ghosh, Swati; Devereaux, Michael W; Anderson, Aimee L; Gehrke, Sarah; Reisz, Julie A; D'Alessandro, Angelo; Orlicky, David J; Lovell, Mark; El Kasmi, Karim C; Shearn, Colin T; Sokol, Ronald J.

Hepatology ; 74(6): 3284-3300, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34310734

5.

Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice.

Takahashi, Shogo; Luo, Yuhuan; Ranjit, Suman; Xie, Cen; Libby, Andrew E; Orlicky, David J; Dvornikov, Alexander; Wang, Xiaoxin X; Myakala, Komuraiah; Jones, Bryce A; Bhasin, Kanchan; Wang, Dong; McManaman, James L; Krausz, Kristopher W; Gratton, Enrico; Ir, Diana; Robertson, Charles E; Frank, Daniel N; Gonzalez, Frank J; Levi, Moshe.

J Biol Chem ; 295(14): 4733-4747, 2020 04 03.

Artigo em Inglês | MEDLINE | ID: mdl-32075905

6.

The developing murine lung is susceptible to acetaminophen toxicity.

Dobrinskikh, Evgenia; Sherlock, Laura G; Orlicky, David J; Zheng, Lijun; De Dios, Robyn; Balasubramaniyan, Durga; Sizemore, Thom; Butler, Brittany; Wright, Clyde J.

Am J Physiol Lung Cell Mol Physiol ; 320(5): L969-L978, 2021 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-33759579

7.

Pulmonary implications of acetaminophen exposures independent of hepatic toxicity.

Dobrinskikh, Evgenia; Al-Juboori, Saif I; Zarate, Miguel A; Zheng, Lijun; De Dios, Robyn; Balasubramaniyan, Durga; Sherlock, Laura G; Orlicky, David J; Wright, Clyde J.

Am J Physiol Lung Cell Mol Physiol ; 321(5): L941-L953, 2021 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-34585971

8.

Using the novel pelvic organ prolapse histologic quantification system to identify phenotypes in uterosacral ligaments in women with pelvic organ prolapse.

Orlicky, David J; Guess, Marsha K; Bales, Elise S; Rascoff, Lauren G; Arruda, Jaime S; Hutchinson-Colas, Juana A; Johnson, Joshua; Connell, Kathleen A.

Am J Obstet Gynecol ; 224(1): 67.e1-67.e18, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33130030

9.

A novel murine model of multi-day moderate ethanol exposure reveals increased intestinal dysfunction and liver inflammation with age.

McMahan, Rachel H; Najarro, Kevin M; Mullen, Juliet E; Paul, Madison T; Orlicky, David J; Hulsebus, Holly J; Kovacs, Elizabeth J.

Immun Ageing ; 18(1): 37, 2021 Sep 23.

Artigo em Inglês | MEDLINE | ID: mdl-34556145

10.

Sugar causes obesity and metabolic syndrome in mice independently of sweet taste.

Andres-Hernando, Ana; Kuwabara, Masanari; Orlicky, David J; Vandenbeuch, Aurelie; Cicerchi, Christina; Kinnamon, Sue C; Finger, Thomas E; Johnson, Richard J; Lanaspa, Miguel A.

Am J Physiol Endocrinol Metab ; 319(2): E276-E290, 2020 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-32574112

11.

AMPK activation in pregnant human myometrial arteries from high-altitude and intrauterine growth-restricted pregnancies.

Lorca, Ramón A; Matarazzo, Christopher J; Bales, Elise S; Houck, Julie A; Orlicky, David J; Euser, Anna G; Julian, Colleen G; Moore, Lorna G.

Am J Physiol Heart Circ Physiol ; 319(1): H203-H212, 2020 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-32502374

12.

Effect of neuronal nitric oxide synthase serine-1412 phosphorylation on hypothalamic-pituitary-ovarian function and leptin response.

Guerra, Damian D; Bok, Rachael; Cari, Evelyn Llerena; Nicholas, Cari; Orlicky, David J; Johnson, Joshua; Hurt, K Joseph.

Biol Reprod ; 102(6): 1281-1289, 2020 05 26.

Artigo em Inglês | MEDLINE | ID: mdl-32101284

13.

Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors.

Dhar, Deepanshi; Raina, Komal; Kumar, Dileep; Wempe, Michael F; Bagby, Stacey M; Pitts, Todd M; Orlicky, David J; Agarwal, Chapla; Messersmith, Wells A; Agarwal, Rajesh.

Mol Carcinog ; 59(10): 1227-1240, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32816368

14.

Correction to: A novel murine model of multi-day moderate ethanol exposure reveals increased intestinal dysfunction and liver inflammation with age.

McMahan, Rachel H; Najarro, Kevin M; Mullen, Juliet E; Paul, Madison T; Orlicky, David J; Hulsebus, Holly J; Kovacs, Elizabeth J.

Immun Ageing ; 18(1): 39, 2021 Oct 21.

Artigo em Inglês | MEDLINE | ID: mdl-34674721

15.

Akt phosphorylation of neuronal nitric oxide synthase regulates gastrointestinal motility in mouse ileum.

Guerra, Damian D; Bok, Rachael; Vyas, Vibhuti; Orlicky, David J; Lorca, Ramón A; Hurt, K Joseph.

Proc Natl Acad Sci U S A ; 116(35): 17541-17546, 2019 08 27.

Artigo em Inglês | MEDLINE | ID: mdl-31405982

16.

TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy.

McLoughlin, Michael R; Orlicky, David J; Prigge, Justin R; Krishna, Pushya; Talago, Emily A; Cavigli, Ian R; Eriksson, Sofi; Miller, Colin G; Kundert, Jean A; Sayin, Volkan I; Sabol, Rachel A; Heinemann, Joshua; Brandenberger, Luke O; Iverson, Sonya V; Bothner, Brian; Papagiannakopoulos, Thales; Shearn, Colin T; Arnér, Elias S J; Schmidt, Edward E.

Proc Natl Acad Sci U S A ; 116(23): 11408-11417, 2019 06 04.

Artigo em Inglês | MEDLINE | ID: mdl-31097586

17.

Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues.

Thompson, Brian; Davidson, Emily A; Chen, Ying; Orlicky, David J; Thompson, David C; Vasiliou, Vasilis.

Chem Biol Interact ; 355: 109804, 2022 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-35123994

18.

Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation.

Schaefer, Rachel E M; Callahan, Rosemary C; Atif, Shaikh M; Orlicky, David J; Cartwright, Ian M; Fontenot, Andrew P; Colgan, Sean P; Onyiah, Joseph C.

Mucosal Immunol ; 15(2): 244-256, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34916594

19.

Age-Related Intestinal Dysbiosis and Enrichment of Gut-specific Bacteria in the Lung Are Associated With Increased Susceptibility to Streptococcus pneumoniae Infection in Mice.

McMahan, Rachel H; Hulsebus, Holly J; Najarro, Kevin M; Giesy, Lauren E; Frank, Daniel N; Orlicky, David J; Kovacs, Elizabeth J.

Front Aging ; 32022.

Artigo em Inglês | MEDLINE | ID: mdl-35392033

20.

Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice.

Hazleton, Keith Z; Martin, Casey G; Orlicky, David J; Arnolds, Kathleen L; Nusbacher, Nichole M; Moreno-Huizar, Nancy; Armstrong, Michael; Reisdorph, Nichole; Lozupone, Catherine A.

NPJ Biofilms Microbiomes ; 8(1): 15, 2022 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-35365681

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