Pesquisa | Portal de Pesquisa da BVS

1.

Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions.

Frost, Adam; Elgort, Marc G; Brandman, Onn; Ives, Clinton; Collins, Sean R; Miller-Vedam, Lakshmi; Weibezahn, Jimena; Hein, Marco Y; Poser, Ina; Mann, Matthias; Hyman, Anthony A; Weissman, Jonathan S.

Cell ; 149(6): 1339-52, 2012 Jun 08.

Artigo em Inglês | MEDLINE | ID: mdl-22682253

2.

RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation.

Guillén-Boixet, Jordina; Kopach, Andrii; Holehouse, Alex S; Wittmann, Sina; Jahnel, Marcus; Schlüßler, Raimund; Kim, Kyoohyun; Trussina, Irmela R E A; Wang, Jie; Mateju, Daniel; Poser, Ina; Maharana, Shovamayee; Ruer-Gruß, Martine; Richter, Doris; Zhang, Xiaojie; Chang, Young-Tae; Guck, Jochen; Honigmann, Alf; Mahamid, Julia; Hyman, Anthony A; Pappu, Rohit V; Alberti, Simon; Franzmann, Titus M.

Cell ; 181(2): 346-361.e17, 2020 04 16.

Artigo em Inglês | MEDLINE | ID: mdl-32302572

3.

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins.

Wang, Jie; Choi, Jeong-Mo; Holehouse, Alex S; Lee, Hyun O; Zhang, Xiaojie; Jahnel, Marcus; Maharana, Shovamayee; Lemaitre, Régis; Pozniakovsky, Andrei; Drechsel, David; Poser, Ina; Pappu, Rohit V; Alberti, Simon; Hyman, Anthony A.

Cell ; 174(3): 688-699.e16, 2018 07 26.

Artigo em Inglês | MEDLINE | ID: mdl-29961577

4.

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.

Cuylen, Sara; Blaukopf, Claudia; Politi, Antonio Z; Müller-Reichert, Thomas; Neumann, Beate; Poser, Ina; Ellenberg, Jan; Hyman, Anthony A; Gerlich, Daniel W.

Nature ; 535(7611): 308-12, 2016 07 14.

Artigo em Inglês | MEDLINE | ID: mdl-27362226

5.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein, Marco Y; Hubner, Nina C; Poser, Ina; Cox, Jürgen; Nagaraj, Nagarjuna; Toyoda, Yusuke; Gak, Igor A; Weisswange, Ina; Mansfeld, Jörg; Buchholz, Frank; Hyman, Anthony A; Mann, Matthias.

Cell ; 163(3): 712-23, 2015 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-26496610

6.

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

Patel, Avinash; Lee, Hyun O; Jawerth, Louise; Maharana, Shovamayee; Jahnel, Marcus; Hein, Marco Y; Stoynov, Stoyno; Mahamid, Julia; Saha, Shambaditya; Franzmann, Titus M; Pozniakovski, Andrej; Poser, Ina; Maghelli, Nicola; Royer, Loic A; Weigert, Martin; Myers, Eugene W; Grill, Stephan; Drechsel, David; Hyman, Anthony A; Alberti, Simon.

Cell ; 162(5): 1066-77, 2015 Aug 27.

Artigo em Inglês | MEDLINE | ID: mdl-26317470

7.

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Bassik, Michael C; Kampmann, Martin; Lebbink, Robert Jan; Wang, Shuyi; Hein, Marco Y; Poser, Ina; Weibezahn, Jimena; Horlbeck, Max A; Chen, Siyuan; Mann, Matthias; Hyman, Anthony A; Leproust, Emily M; McManus, Michael T; Weissman, Jonathan S.

Cell ; 152(4): 909-22, 2013 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-23394947

8.

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.

Neumann, Beate; Walter, Thomas; Hériché, Jean-Karim; Bulkescher, Jutta; Erfle, Holger; Conrad, Christian; Rogers, Phill; Poser, Ina; Held, Michael; Liebel, Urban; Cetin, Cihan; Sieckmann, Frank; Pau, Gregoire; Kabbe, Rolf; Wünsche, Annelie; Satagopam, Venkata; Schmitz, Michael H A; Chapuis, Catherine; Gerlich, Daniel W; Schneider, Reinhard; Eils, Roland; Huber, Wolfgang; Peters, Jan-Michael; Hyman, Anthony A; Durbin, Richard; Pepperkok, Rainer; Ellenberg, Jan.

Nature ; 464(7289): 721-7, 2010 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-20360735

9.

Protein Dynamics in Complex DNA Lesions.

Aleksandrov, Radoslav; Dotchev, Anton; Poser, Ina; Krastev, Dragomir; Georgiev, Georgi; Panova, Greta; Babukov, Yordan; Danovski, Georgi; Dyankova, Teodora; Hubatsch, Lars; Ivanova, Aneliya; Atemin, Aleksandar; Nedelcheva-Veleva, Marina N; Hasse, Susanne; Sarov, Mihail; Buchholz, Frank; Hyman, Anthony A; Grill, Stephan W; Stoynov, Stoyno S.

Mol Cell ; 69(6): 1046-1061.e5, 2018 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-29547717

10.

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

Ganassi, Massimo; Mateju, Daniel; Bigi, Ilaria; Mediani, Laura; Poser, Ina; Lee, Hyun O; Seguin, Samuel J; Morelli, Federica F; Vinet, Jonathan; Leo, Giuseppina; Pansarasa, Orietta; Cereda, Cristina; Poletti, Angelo; Alberti, Simon; Carra, Serena.

Mol Cell ; 63(5): 796-810, 2016 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-27570075

11.

SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export.

Müller-McNicoll, Michaela; Botti, Valentina; de Jesus Domingues, Antonio M; Brandl, Holger; Schwich, Oliver D; Steiner, Michaela C; Curk, Tomaz; Poser, Ina; Zarnack, Kathi; Neugebauer, Karla M.

Genes Dev ; 30(5): 553-66, 2016 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-26944680

12.

Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin.

Mediani, Laura; Guillén-Boixet, Jordina; Vinet, Jonathan; Franzmann, Titus M; Bigi, Ilaria; Mateju, Daniel; Carrà, Arianna D; Morelli, Federica F; Tiago, Tatiana; Poser, Ina; Alberti, Simon; Carra, Serena.

EMBO J ; 38(15): e101341, 2019 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-31271238

13.

The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.

Ivanov, Miroslav P; Ladurner, Rene; Poser, Ina; Beveridge, Rebecca; Rampler, Evelyn; Hudecz, Otto; Novatchkova, Maria; Hériché, Jean-Karim; Wutz, Gordana; van der Lelij, Petra; Kreidl, Emanuel; Hutchins, James Ra; Axelsson-Ekker, Heinz; Ellenberg, Jan; Hyman, Anthony A; Mechtler, Karl; Peters, Jan-Michael.

EMBO J ; 37(15)2018 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-29930102

14.

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.

Poser, Ina; Sarov, Mihail; Hutchins, James R A; Hériché, Jean-Karim; Toyoda, Yusuke; Pozniakovsky, Andrei; Weigl, Daniela; Nitzsche, Anja; Hegemann, Björn; Bird, Alexander W; Pelletier, Laurence; Kittler, Ralf; Hua, Sujun; Naumann, Ronald; Augsburg, Martina; Sykora, Martina M; Hofemeister, Helmut; Zhang, Youming; Nasmyth, Kim; White, Kevin P; Dietzel, Steffen; Mechtler, Karl; Durbin, Richard; Stewart, A Francis; Peters, Jan-Michael; Buchholz, Frank; Hyman, Anthony A.

Nat Methods ; 5(5): 409-15, 2008 May.

Artigo em Inglês | MEDLINE | ID: mdl-18391959

15.

Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth.

Heissenberger, Clemens; Liendl, Lisa; Nagelreiter, Fabian; Gonskikh, Yulia; Yang, Guohuan; Stelzer, Elena M; Krammer, Teresa L; Micutkova, Lucia; Vogt, Stefan; Kreil, David P; Sekot, Gerhard; Siena, Emilio; Poser, Ina; Harreither, Eva; Linder, Angela; Ehret, Viktoria; Helbich, Thomas H; Grillari-Voglauer, Regina; Jansen-Dürr, Pidder; Kos, Martin; Polacek, Norbert; Grillari, Johannes; Schosserer, Markus.

Nucleic Acids Res ; 47(22): 11807-11825, 2019 12 16.

Artigo em Inglês | MEDLINE | ID: mdl-31722427

16.

Binding Dynamics of α-Actinin-4 in Dependence of Actin Cortex Tension.

Hosseini, Kamran; Sbosny, Leon; Poser, Ina; Fischer-Friedrich, Elisabeth.

Biophys J ; 119(6): 1091-1107, 2020 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-32853564

17.

CPAP promotes timely cilium disassembly to maintain neural progenitor pool.

Gabriel, Elke; Wason, Arpit; Ramani, Anand; Gooi, Li Ming; Keller, Patrick; Pozniakovsky, Andrei; Poser, Ina; Noack, Florian; Telugu, Narasimha Swamy; Calegari, Federico; Saric, Tomo; Hescheler, Jürgen; Hyman, Anthony A; Gottardo, Marco; Callaini, Giuliano; Alkuraya, Fowzan Sami; Gopalakrishnan, Jay.

EMBO J ; 35(8): 803-19, 2016 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-26929011

18.

Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis.

Özlü, Nurhan; Qureshi, Mohammad H; Toyoda, Yusuke; Renard, Bernhard Y; Mollaoglu, Gürkan; Özkan, Nazli E; Bulbul, Selda; Poser, Ina; Timm, Wiebke; Hyman, Anthony A; Mitchison, Timothy J; Steen, Judith A.

EMBO J ; 34(2): 251-65, 2015 Jan 13.

Artigo em Inglês | MEDLINE | ID: mdl-25476450

19.

Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins.

Skogs, Marie; Stadler, Charlotte; Schutten, Rutger; Hjelmare, Martin; Gnann, Christian; Björk, Lars; Poser, Ina; Hyman, Anthony; Uhlén, Mathias; Lundberg, Emma.

J Proteome Res ; 16(1): 147-155, 2017 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-27723985

20.

PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.

Guerrera, Diego; Shah, Jimit; Vasileva, Ekaterina; Sluysmans, Sophie; Méan, Isabelle; Jond, Lionel; Poser, Ina; Mann, Matthias; Hyman, Anthony A; Citi, Sandra.

J Biol Chem ; 291(21): 11016-29, 2016 May 20.

Artigo em Inglês | MEDLINE | ID: mdl-27044745

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