Pesquisa | Portal de Pesquisa da BVS

1.

T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation.

Bachmann, Michael P; Bartsch, Tabea; Bippes, Claudia C; Bachmann, Dominik; Puentes-Cala, Edinson; Bachmann, Jennifer; Bartsch, Holger; Arndt, Claudia; Koristka, Stefanie; Loureiro, Liliana R; Kegler, Alexandra; Laube, Markus; Gross, Joanne K; Gross, Tim; Kurien, Biji T; Scofield, R Hal; Farris, A Darise; James, Judith A; Schmitz, Marc; Feldmann, Anja.

Int J Mol Sci ; 22(3)2021 Jan 26.

Artigo em Inglês | MEDLINE | ID: mdl-33530489

2.

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

Patel, Zubin H; Lu, Xiaoming; Miller, Daniel; Forney, Carmy R; Lee, Joshua; Lynch, Arthur; Schroeder, Connor; Parks, Lois; Magnusen, Albert F; Chen, Xiaoting; Pujato, Mario; Maddox, Avery; Zoller, Erin E; Namjou, Bahram; Brunner, Hermine I; Henrickson, Michael; Huggins, Jennifer L; Williams, Adrienne H; Ziegler, Julie T; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Adler, Adam; Shen, Nan; Nath, Swapan K; Stevens, Anne M; Freedman, Barry I; Pons-Estel, Bernardo A; Tsao, Betty P; Jacob, Chaim O; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Martin, Javier; Reveille, John D; Anaya, Juan-Manuel; James, Judith A; Sivils, Kathy L; Criswell, Lindsey A; Vilá, Luis M; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Edberg, Jeffrey C; Ramsey-Goldman, Rosalind; Bang, So-Young; Lee, Hye-Soon; Bae, Sang-Cheol; Boackle, Susan A.

Hum Mol Genet ; 27(13): 2392-2404, 2018 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-29912393

3.

Baseline disease activity influences subsequent achievement of patient acceptable symptom state in Sjögren's syndrome.

Park, Eun Hye; Ha, You-Jung; Kang, Eun Ha; Song, Yeong Wook; Scofield, R Hal; Lee, Yun Jong.

Rheumatology (Oxford) ; 2020 Nov 14.

Artigo em Inglês | MEDLINE | ID: mdl-33188390

4.

Genetics in Sjögren's syndrome: where we are and where we go.

Harris, Valerie M; Scofield, R Hal; Sivils, Kathy L.

Clin Exp Rheumatol ; 37 Suppl 118(3): 234-239, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31464674

5.

Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.

Lu, Xiaoming; Zoller, Erin E; Weirauch, Matthew T; Wu, Zhiguo; Namjou, Bahram; Williams, Adrienne H; Ziegler, Julie T; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Adler, Adam; Shen, Nan; Nath, Swapan K; Stevens, Anne M; Freedman, Barry I; Tsao, Betty P; Jacob, Chaim O; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Reveille, John D; Anaya, Juan-Manuel; James, Judith A; Sivils, Kathy L; Criswell, Lindsey A; Vilá, Luis M; Alarcón-Riquelme, Marta E; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Ramsey-Goldman, Rosalind; Joo, Young Bin; Choi, Jeongim; Bae, Sang-Cheol; Boackle, Susan A; Graham, Deborah Cunninghame; Vyse, Timothy J; Guthridge, Joel M; Gaffney, Patrick M; Langefeld, Carl D; Kelly, Jennifer A; Greis, Kenneth D; Kaufman, Kenneth M; Harley, John B; Kottyan, Leah C.

Am J Hum Genet ; 96(5): 731-9, 2015 May 07.

Artigo em Inglês | MEDLINE | ID: mdl-25865496

6.

Minor salivary gland fibrosis in Sjögren's syndrome is elevated, associated with focus score and not solely a consequence of aging.

Leehan, Kerry M; Pezant, Nathan P; Rasmussen, Astrid; Grundahl, Kiely; Moore, Jacen S; Radfar, Lida; Lewis, David M; Stone, Donald U; Lessard, Christopher J; Rhodus, Nelson L; Segal, Barbara M; Scofield, R Hal; Sivils, Kathy L; Montgomery, Courtney; Farris, A Darise.

Clin Exp Rheumatol ; 36 Suppl 112(3): 80-88, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29148407

7.

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Kottyan, Leah C; Zoller, Erin E; Bene, Jessica; Lu, Xiaoming; Kelly, Jennifer A; Rupert, Andrew M; Lessard, Christopher J; Vaughn, Samuel E; Marion, Miranda; Weirauch, Matthew T; Namjou, Bahram; Adler, Adam; Rasmussen, Astrid; Glenn, Stuart; Montgomery, Courtney G; Hirschfield, Gideon M; Xie, Gang; Coltescu, Catalina; Amos, Chris; Li, He; Ice, John A; Nath, Swapan K; Mariette, Xavier; Bowman, Simon; Rischmueller, Maureen; Lester, Sue; Brun, Johan G; Gøransson, Lasse G; Harboe, Erna; Omdal, Roald; Cunninghame-Graham, Deborah S; Vyse, Tim; Miceli-Richard, Corinne; Brennan, Michael T; Lessard, James A; Wahren-Herlenius, Marie; Kvarnström, Marika; Illei, Gabor G; Witte, Torsten; Jonsson, Roland; Eriksson, Per; Nordmark, Gunnel; Ng, Wan-Fai; Anaya, Juan-Manuel; Rhodus, Nelson L; Segal, Barbara M; Merrill, Joan T; James, Judith A; Guthridge, Joel M; Scofield, R Hal.

Hum Mol Genet ; 24(2): 582-96, 2015 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-25205108

8.

Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.

Guthridge, Joel M; Lu, Rufei; Sun, Harry; Sun, Celi; Wiley, Graham B; Dominguez, Nicolas; Macwana, Susan R; Lessard, Christopher J; Kim-Howard, Xana; Cobb, Beth L; Kaufman, Kenneth M; Kelly, Jennifer A; Langefeld, Carl D; Adler, Adam J; Harley, Isaac T W; Merrill, Joan T; Gilkeson, Gary S; Kamen, Diane L; Niewold, Timothy B; Brown, Elizabeth E; Edberg, Jeffery C; Petri, Michelle A; Ramsey-Goldman, Rosalind; Reveille, John D; Vilá, Luis M; Kimberly, Robert P; Freedman, Barry I; Stevens, Anne M; Boackle, Susan A; Criswell, Lindsey A; Vyse, Tim J; Behrens, Timothy W; Jacob, Chaim O; Alarcón-Riquelme, Marta E; Sivils, Kathy L; Choi, Jiyoung; Joo, Young Bin; Bang, So-Young; Lee, Hye-Soon; Bae, Sang-Cheol; Shen, Nan; Qian, Xiaoxia; Tsao, Betty P; Scofield, R Hal; Harley, John B; Webb, Carol F; Wakeland, Edward K; James, Judith A; Nath, Swapan K; Graham, Robert R.

Am J Hum Genet ; 94(4): 586-98, 2014 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-24702955

9.

Familial Pallister-Hall in adulthood.

Talsania, Mitali; Sharma, Rohan; Sughrue, Michael E; Scofield, R Hal; Lim, Jonea.

Neuro Endocrinol Lett ; 38(5): 329-331, 2017 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-29106787

10.

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.

Harris, Valerie M; Sharma, Rohan; Cavett, Joshua; Kurien, Biji T; Liu, Ke; Koelsch, Kristi A; Rasmussen, Astrid; Radfar, Lida; Lewis, David; Stone, Donald U; Kaufman, C Erick; Li, Shibo; Segal, Barbara; Wallace, Daniel J; Weisman, Michael H; Venuturupalli, Swamy; Kelly, Jennifer A; Alarcon-Riquelme, Marta E; Pons-Estel, Bernardo; Jonsson, Roland; Lu, Xianglan; Gottenberg, Jacques-Eric; Anaya, Juan-Manuel; Cunninghame-Graham, Deborah S; Huang, Andrew J W; Brennan, Michael T; Hughes, Pamela; Alevizos, Ilias; Miceli-Richard, Corinne; Keystone, Edward C; Bykerk, Vivian P; Hirschfield, Gideon; Xie, Gang; Siminovitch, Katherine A; Ng, Wan-Fai; Nordmark, Gunnel; Bucher, Sara Magnusson; Eriksson, Per; Omdal, Roald; Rhodus, Nelson L; Rischmueller, Maureen; Rohrer, Michael; Wahren-Herlenius, Marie; Witte, Torsten; Mariette, Xavier; Lessard, Christopher J; Harley, John B; Sivils, Kathy L; Scofield, R Hal.

Clin Immunol ; 168: 25-29, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27109640

11.

Interaction between innate immunity and Ro52-induced antibody causes Sjögren's syndrome-like disorder in mice.

Szczerba, Barbara M; Kaplonek, Paulina; Wolska, Nina; Podsiadlowska, Anna; Rybakowska, Paulina D; Dey, Paromita; Rasmussen, Astrid; Grundahl, Kiely; Hefner, Kimberly S; Stone, Donald U; Young, Stephen; Lewis, David M; Radfar, Lida; Scofield, R Hal; Sivils, Kathy L; Bagavant, Harini; Deshmukh, Umesh S.

Ann Rheum Dis ; 75(3): 617-22, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25906316

12.

Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.

Deng, Yun; Zhao, Jian; Sakurai, Daisuke; Sestak, Andrea L; Osadchiy, Vadim; Langefeld, Carl D; Kaufman, Kenneth M; Kelly, Jennifer A; James, Judith A; Petri, Michelle A; Bae, Sang-Cheol; Alarcón-Riquelme, Marta E; Alarcón, Graciela S; Anaya, Juan-Manuel; Criswell, Lindsey A; Freedman, Barry I; Kamen, Diane L; Gilkeson, Gary S; Jacob, Chaim O; Merrill, Joan T; Gaffney, Patrick M; Sivils, Kathy Moser; Niewold, Timothy B; Ramsey-Goldman, Rosalind; Reveille, John D; Scofield, R Hal; Stevens, Anne M; Boackle, Susan A; Vilá, Luis M; Sohn, I I Woong; Lee, Seung; Chang, Deh-Ming; Song, Yeong Wook; Vyse, Timothy J; Harley, John B; Brown, Elizabeth E; Edberg, Jeffrey C; Kimberly, Robert P; Cantor, Rita M; Hahn, Bevra H; Grossman, Jennifer M; Tsao, Betty P.

Ann Rheum Dis ; 75(11): 2007-2013, 2016 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-26783109

13.

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.

Zhao, Jian; Giles, Brendan M; Taylor, Rhonda L; Yette, Gabriel A; Lough, Kara M; Ng, Han Leng; Abraham, Lawrence J; Wu, Hui; Kelly, Jennifer A; Glenn, Stuart B; Adler, Adam J; Williams, Adrienne H; Comeau, Mary E; Ziegler, Julie T; Marion, Miranda; Alarcón-Riquelme, Marta E; Alarcón, Graciela S; Anaya, Juan-Manuel; Bae, Sang-Cheol; Kim, Dam; Lee, Hye-Soon; Criswell, Lindsey A; Freedman, Barry I; Gilkeson, Gary S; Guthridge, Joel M; Jacob, Chaim O; James, Judith A; Kamen, Diane L; Merrill, Joan T; Sivils, Kathy Moser; Niewold, Timothy B; Petri, Michelle A; Ramsey-Goldman, Rosalind; Reveille, John D; Scofield, R Hal; Stevens, Anne M; Vilá, Luis M; Vyse, Timothy J; Kaufman, Kenneth M; Harley, John B; Langefeld, Carl D; Gaffney, Patrick M; Brown, Elizabeth E; Edberg, Jeffrey C; Kimberly, Robert P; Ulgiati, Daniela; Tsao, Betty P; Boackle, Susan A.

Ann Rheum Dis ; 75(1): 242-52, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25180293

14.

Previous diagnosis of Sjögren's Syndrome as rheumatoid arthritis or systemic lupus erythematosus.

Rasmussen, Astrid; Radfar, Lida; Lewis, David; Grundahl, Kiely; Stone, Donald U; Kaufman, C Erick; Rhodus, Nelson L; Segal, Barbara; Wallace, Daniel J; Weisman, Michael H; Venuturupalli, Swamy; Kurien, Biji T; Lessard, Christopher J; Sivils, Kathy L; Scofield, R Hal.

Rheumatology (Oxford) ; 55(7): 1195-201, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-26998859

15.

Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

Manku, Harinder; Langefeld, Carl D; Guerra, Sandra G; Malik, Talat H; Alarcon-Riquelme, Marta; Anaya, Juan-Manuel; Bae, Sang-Cheol; Boackle, Susan A; Brown, Elizabeth E; Criswell, Lindsey A; Freedman, Barry I; Gaffney, Patrick M; Gregersen, Peter A; Guthridge, Joel M; Han, Sang-Hoon; Harley, John B; Jacob, Chaim O; James, Judith A; Kamen, Diane L; Kaufman, Kenneth M; Kelly, Jennifer A; Martin, Javier; Merrill, Joan T; Moser, Kathy L; Niewold, Timothy B; Park, So-Yeon; Pons-Estel, Bernardo A; Sawalha, Amr H; Scofield, R Hal; Shen, Nan; Stevens, Anne M; Sun, Celi; Gilkeson, Gary S; Edberg, Jeff C; Kimberly, Robert P; Nath, Swapan K; Tsao, Betty P; Vyse, Tim J.

PLoS Genet ; 9(7): e1003554, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23874208

16.

MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.

Deng, Yun; Zhao, Jian; Sakurai, Daisuke; Kaufman, Kenneth M; Edberg, Jeffrey C; Kimberly, Robert P; Kamen, Diane L; Gilkeson, Gary S; Jacob, Chaim O; Scofield, R Hal; Langefeld, Carl D; Kelly, Jennifer A; Ramsey-Goldman, Rosalind; Petri, Michelle A; Reveille, John D; Vilá, Luis M; Alarcón, Graciela S; Vyse, Timothy J; Pons-Estel, Bernardo A; Freedman, Barry I; Gaffney, Patrick M; Sivils, Kathy Moser; James, Judith A; Gregersen, Peter K; Anaya, Juan-Manuel; Niewold, Timothy B; Merrill, Joan T; Criswell, Lindsey A; Stevens, Anne M; Boackle, Susan A; Cantor, Rita M; Chen, Weiling; Grossman, Jeniffer M; Hahn, Bevra H; Harley, John B; AlarcÏn-Riquelme, Marta E; Brown, Elizabeth E; Tsao, Betty P.

PLoS Genet ; 9(2): e1003336, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23468661

17.

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.

Molineros, Julio E; Maiti, Amit K; Sun, Celi; Looger, Loren L; Han, Shizhong; Kim-Howard, Xana; Glenn, Stuart; Adler, Adam; Kelly, Jennifer A; Niewold, Timothy B; Gilkeson, Gary S; Brown, Elizabeth E; Alarcón, Graciela S; Edberg, Jeffrey C; Petri, Michelle; Ramsey-Goldman, Rosalind; Reveille, John D; Vilá, Luis M; Freedman, Barry I; Tsao, Betty P; Criswell, Lindsey A; Jacob, Chaim O; Moore, Jason H; Vyse, Timothy J; Langefeld, Carl L; Guthridge, Joel M; Gaffney, Patrick M; Moser, Kathy L; Scofield, R Hal; Alarcón-Riquelme, Marta E; Williams, Scott M; Merrill, Joan T; James, Judith A; Kaufman, Kenneth M; Kimberly, Robert P; Harley, John B; Nath, Swapan K.

PLoS Genet ; 9(2): e1003222, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23441136

18.

Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.

Sakurai, Daisuke; Zhao, Jian; Deng, Yun; Kelly, Jennifer A; Brown, Elizabeth E; Harley, John B; Bae, Sang-Cheol; AlarcÏn-Riquelme, Marta E; Edberg, Jeffrey C; Kimberly, Robert P; Ramsey-Goldman, Rosalind; Petri, Michelle A; Reveille, John D; Vilá, Luis M; Alarcón, Graciela S; Kaufman, Kenneth M; Vyse, Timothy J; Jacob, Chaim O; Gaffney, Patrick M; Sivils, Kathy Moser; James, Judith A; Kamen, Diane L; Gilkeson, Gary S; Niewold, Timothy B; Merrill, Joan T; Scofield, R Hal; Criswell, Lindsey A; Stevens, Anne M; Boackle, Susan A; Kim, Jae-Hoon; Choi, Jiyoung; Pons-Estel, Bernardo A; Freedman, Barry I; Anaya, Juan-Manuel; Martin, Javier; Yu, C Yung; Chang, Deh-Ming; Song, Yeong Wook; Langefeld, Carl D; Chen, Weiling; Grossman, Jennifer M; Cantor, Rita M; Hahn, Bevra H; Tsao, Betty P.

PLoS Genet ; 9(10): e1003870, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24130510

19.

Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.

Zhao, Jian; Wu, Hui; Langefeld, Carl D; Kaufman, Kenneth M; Kelly, Jennifer A; Bae, Sang-Cheol; Alarcón, Graciela S; Anaya, Juan-Manuel; Criswell, Lindsey A; Freedman, Barry I; Kamen, Diane L; Gilkeson, Gary S; Jacob, Chaim O; James, Judith A; Merrill, Joan T; Gaffney, Patrick M; Sivils, Kathy Moser; Niewold, Timothy B; Petri, Michelle A; Song, Seung Taek; Jeong, Hye-Jin; Ramsey-Goldman, Rosalind; Reveille, John D; Scofield, R Hal; Stevens, Anne M; Boackle, Susan A; Vilá, Luis M; Chang, Deh-Ming; Song, Yeong Wook; Vyse, Timothy J; Harley, John B; Brown, Elizabeth E; Edberg, Jeffrey C; Kimberly, Robert P; Hahn, Bevra H; Grossman, Jennifer M; Tsao, Betty P; La Cava, Antonio.

Clin Immunol ; 161(2): 157-62, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26385092

20.

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.

Lessard, Christopher J; Adrianto, Indra; Ice, John A; Wiley, Graham B; Kelly, Jennifer A; Glenn, Stuart B; Adler, Adam J; Li, He; Rasmussen, Astrid; Williams, Adrienne H; Ziegler, Julie; Comeau, Mary E; Marion, Miranda; Wakeland, Benjamin E; Liang, Chaoying; Ramos, Paula S; Grundahl, Kiely M; Gallant, Caroline J; Alarcón-Riquelme, Marta E; Alarcón, Graciela S; Anaya, Juan-Manuel; Bae, Sang-Cheol; Boackle, Susan A; Brown, Elizabeth E; Chang, Deh-Ming; Cho, Soo-Kyung; Criswell, Lindsey A; Edberg, Jeffrey C; Freedman, Barry I; Gilkeson, Gary S; Jacob, Chaim O; James, Judith A; Kamen, Diane L; Kimberly, Robert P; Kim, Jae-Hoon; Martin, Javier; Merrill, Joan T; Niewold, Timothy B; Park, So-Yeon; Petri, Michelle A; Pons-Estel, Bernardo A; Ramsey-Goldman, Rosalind; Reveille, John D; Scofield, R Hal; Song, Yeong Wook; Stevens, Anne M; Tsao, Betty P; Vila, Luis M; Vyse, Timothy J; Yu, Chack-Yung.

Am J Hum Genet ; 90(4): 648-60, 2012 Apr 06.

Artigo em Inglês | MEDLINE | ID: mdl-22464253

Portal de Pesquisa da BVS

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: