Pesquisa | Portal de Pesquisa da BVS

1.

XBP1 variant 1 (Xv1) promotes mitosis of cancer cells involving upregulation of the polyglutamylase TTLL6.

Zhong, Yongwang; Yan, Wenjing; Ruan, Jingjing; Fang, Mike; Yu, Changjun; Du, Shaojun; Rai, Ganesha; Tao, Dingyin; Henderson, Mark J; Fang, Shengyun.

Hum Mol Genet ; 2022 Mar 25.

Artigo em Inglês | MEDLINE | ID: mdl-35333353

2.

A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells.

Chen, Yu; Tristan, Carlos A; Chen, Lu; Jovanovic, Vukasin M; Malley, Claire; Chu, Pei-Hsuan; Ryu, Seungmi; Deng, Tao; Ormanoglu, Pinar; Tao, Dingyin; Fang, Yuhong; Slamecka, Jaroslav; Hong, Hyenjong; LeClair, Christopher A; Michael, Sam; Austin, Christopher P; Simeonov, Anton; Singeç, Ilyas.

Nat Methods ; 18(5): 528-541, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33941937

3.

Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases.

Wiedmann, Mareike; Dranchak, Patricia K; Aitha, Mahesh; Queme, Bryan; Collmus, Christopher D; Kashipathy, Maithri M; Kanter, Liza; Lamy, Laurence; Rogers, Joseph M; Tao, Dingyin; Battaile, Kevin P; Rai, Ganesha; Lovell, Scott; Suga, Hiroaki; Inglese, James.

J Biol Chem ; 296: 100628, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33812994

4.

A Universal and High-Throughput Proteomics Sample Preparation Platform.

Burns, Andrew P; Zhang, Ya-Qin; Xu, Tuan; Wei, Zhengxi; Yao, Qin; Fang, Yuhong; Cebotaru, Valeriu; Xia, Menghang; Hall, Matthew D; Huang, Ruili; Simeonov, Anton; LeClair, Christopher A; Tao, Dingyin.

Anal Chem ; 93(24): 8423-8431, 2021 06 22.

Artigo em Inglês | MEDLINE | ID: mdl-34110797

5.

A direct peptide reactivity assay using a high-throughput mass spectrometry screening platform for detection of skin sensitizers.

Wei, Zhengxi; Fang, Yuhong; Gosztyla, Maya L; Li, Andrew J; Huang, Wenwei; LeClair, Christopher A; Simeonov, Anton; Tao, Dingyin; Xia, Menghang.

Toxicol Lett ; 338: 67-77, 2021 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-33290830

6.

High-throughput protein modification quantitation analysis using intact protein MRM and its application on hENGase inhibitor screening.

Tao, Dingyin; Xu, Miao; Farkhondeh, Atena; Burns, Andrew P; Rodems, Steven; Might, Matthew; Zheng, Wei; LeClair, Christopher A.

Talanta ; 231: 122384, 2021 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-33965046

7.

Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.

Liu, Li; Tang, Manshu; Pragani, Rajan; Whitby, Frank G; Zhang, Ya-Qin; Balakrishnan, Bijina; Fang, Yuhong; Karavadhi, Surendra; Tao, Dingyin; LeClair, Christopher A; Hall, Matthew D; Marugan, Juan J; Boxer, Matthew; Shen, Min; Hill, Christopher P; Lai, Kent; Patnaik, Samarjit.

J Med Chem ; 64(18): 13551-13571, 2021 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-34491744

8.

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.

Henderson, Mark J; Trychta, Kathleen A; Yang, Shyh-Ming; Bäck, Susanne; Yasgar, Adam; Wires, Emily S; Danchik, Carina; Yan, Xiaokang; Yano, Hideaki; Shi, Lei; Wu, Kuo-Jen; Wang, Amy Q; Tao, Dingyin; Zahoránszky-Kohalmi, Gergely; Hu, Xin; Xu, Xin; Maloney, David; Zakharov, Alexey V; Rai, Ganesha; Urano, Fumihiko; Airavaara, Mikko; Gavrilova, Oksana; Jadhav, Ajit; Wang, Yun; Simeonov, Anton; Harvey, Brandon K.

Cell Rep ; 35(4): 109040, 2021 04 27.

Artigo em Inglês | MEDLINE | ID: mdl-33910017

9.

Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.

Clausse, Victor; Tao, Dingyin; Debnath, Subrata; Fang, Yuhong; Tagad, Harichandra D; Wang, Yuhong; Sun, Hongmao; LeClair, Christopher A; Mazur, Sharlyn J; Lane, Kelly; Shi, Zhen-Dan; Vasalatiy, Olga; Eells, Rebecca; Baker, Lynn K; Henderson, Mark J; Webb, Martin R; Shen, Min; Hall, Matthew D; Appella, Ettore; Appella, Daniel H; Coussens, Nathan P.

J Biol Chem ; 294(46): 17654-17668, 2019 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-31481464

10.

Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties.

Rai, Ganesha; Urban, Daniel J; Mott, Bryan T; Hu, Xin; Yang, Shyh-Ming; Benavides, Gloria A; Johnson, Michelle S; Squadrito, Giuseppe L; Brimacombe, Kyle R; Lee, Tobie D; Cheff, Dorian M; Zhu, Hu; Henderson, Mark J; Pohida, Katherine; Sulikowski, Gary A; Dranow, David M; Kabir, Md; Shah, Pranav; Padilha, Elias; Tao, Dingyin; Fang, Yuhong; Christov, Plamen P; Kim, Kwangho; Jana, Somnath; Muttil, Pavan; Anderson, Tamara; Kunda, Nitesh K; Hathaway, Helen J; Kusewitt, Donna F; Oshima, Nobu; Cherukuri, Murali; Davies, Douglas R; Norenberg, Jeffrey P; Sklar, Larry A; Moore, William J; Dang, Chi V; Stott, Gordon M; Neckers, Leonard; Flint, Andrew J; Darley-Usmar, Victor M; Simeonov, Anton; Waterson, Alex G; Jadhav, Ajit; Hall, Matthew D; Maloney, David J.

J Med Chem ; 63(19): 10984-11011, 2020 10 08.

Artigo em Inglês | MEDLINE | ID: mdl-32902275

11.

Serially coupled microcolumn reversed phase liquid chromatography for shotgun proteomic analysis.

Tao, Dingyin; Zhu, Guijie; Sun, Liangliang; Ma, Junfeng; Liang, Zhen; Zhang, Weibing; Zhang, Lihua; Zhang, Yukui.

Proteomics ; 9(7): 2029-36, 2009 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-19294701

12.

Integrated platform for proteome analysis with combination of protein and peptide separation via online digestion.

Yuan, Huiming; Zhang, Lihua; Hou, Chunyan; Zhu, Guijie; Tao, Dingyin; Liang, Zhen; Zhang, Yukui.

Anal Chem ; 81(21): 8708-14, 2009 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-19788244

13.

Microchip free flow planar reversed phase electrochromatography with monolithic stationary phase.

Wang, Pingli; Tao, Dingyin; Zhang, Lihua; Liang, Zhen; Zhang, Yukui.

J Sep Sci ; 32(15-16): 2629-34, 2009 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-19585531

14.

Organic-inorganic hybrid silica monolith based immobilized trypsin reactor with high enzymatic activity.

Ma, Junfeng; Liang, Zhen; Qiao, Xiaoqiang; Deng, Qiliang; Tao, Dingyin; Zhang, Lihua; Zhang, Yukui.

Anal Chem ; 80(8): 2949-56, 2008 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-18333626

15.

Molecular Profiling of Phagocytic Immune Cells in Anopheles gambiae Reveals Integral Roles for Hemocytes in Mosquito Innate Immunity.

Smith, Ryan C; King, Jonas G; Tao, Dingyin; Zeleznik, Oana A; Brando, Clara; Thallinger, Gerhard G; Dinglasan, Rhoel R.

Mol Cell Proteomics ; 15(11): 3373-3387, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27624304

16.

The Nonartemisinin Sesquiterpene Lactones Parthenin and Parthenolide Block Plasmodium falciparum Sexual Stage Transmission.

Balaich, Jared N; Mathias, Derrick K; Torto, Baldwyn; Jackson, Bryan T; Tao, Dingyin; Ebrahimi, Babak; Tarimo, Brian B; Cheseto, Xavier; Foster, Woodbridge A; Dinglasan, Rhoel R.

Antimicrob Agents Chemother ; 60(4): 2108-17, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26787692

17.

The acute transcriptomic and proteomic response of HC-04 hepatoma cells to hepatocyte growth factor and its implications for Plasmodium falciparum sporozoite invasion.

Tao, Dingyin; King, Jonas G; Tweedell, Rebecca E; Jost, Philipp J; Boddey, Justin A; Dinglasan, Rhoel R.

Mol Cell Proteomics ; 13(5): 1153-64, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24532842

18.

Sex-partitioning of the Plasmodium falciparum stage V gametocyte proteome provides insight into falciparum-specific cell biology.

Tao, Dingyin; Ubaida-Mohien, Ceereena; Mathias, Derrick K; King, Jonas G; Pastrana-Mena, Rebecca; Tripathi, Abhai; Goldowitz, Ilana; Graham, David R; Moss, Eli; Marti, Matthias; Dinglasan, Rhoel R.

Mol Cell Proteomics ; 13(10): 2705-24, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25056935

19.

The cellular and proteomic response of primary and immortalized murine Kupffer cells following immune stimulation diverges from that of monocyte-derived macrophages.

Tweedell, Rebecca; Tao, Dingyin; Dinglasan, Rhoel R.

Proteomics ; 15(2-3): 545-53, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25266554

20.

Integrated microfluidic chip and online SCX separation allows untargeted nanoscale metabolomic and peptidomic profiling.

Tharakan, Ravi; Tao, Dingyin; Ubaida-Mohien, Ceereena; Dinglasan, Rhoel R; Graham, David R.

J Proteome Res ; 14(3): 1621-6, 2015 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-25574574

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