Pesquisa | Portal de Pesquisa da BVS

1.

Reactive Center Loop (RCL) Peptides Derived from Serpins Display Independent Coagulation and Immune Modulating Activities.

Ambadapadi, Sriram; Munuswamy-Ramanujam, Ganesh; Zheng, Donghang; Sullivan, Colin; Dai, Erbin; Morshed, Sufi; McFadden, Baron; Feldman, Emily; Pinard, Melissa; McKenna, Robert; Tibbetts, Scott; Lucas, Alexandra.

J Biol Chem ; 291(6): 2874-87, 2016 Feb 05.

Artigo em Inglês | MEDLINE | ID: mdl-26620556

2.

Periodontal pathogens invade gingiva and aortic adventitia and elicit inflammasome activation in αvß6 integrin-deficient mice.

Velsko, Irina M; Chukkapalli, Sasanka S; Rivera-Kweh, Mercedes F; Zheng, Donghang; Aukhil, Ikramuddin; Lucas, Alexandra R; Larjava, Hannu; Kesavalu, Lakshmyya.

Infect Immun ; 83(12): 4582-93, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26371120

3.

Invasion of oral and aortic tissues by oral spirochete Treponema denticola in ApoE(-/-) mice causally links periodontal disease and atherosclerosis.

Chukkapalli, Sasanka S; Rivera, Mercedes F; Velsko, Irina M; Lee, Ju-Youn; Chen, Hao; Zheng, Donghang; Bhattacharyya, Indraneel; Gangula, Pandu R; Lucas, Alexandra R; Kesavalu, Lakshmyya.

Infect Immun ; 82(5): 1959-67, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24566627

4.

Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection.

Chen, Hao; Zheng, Donghang; Abbott, Jeff; Liu, Liying; Bartee, Mee Y; Long, Maureen; Davids, Jennifer; Williams, Jennifer; Feldmann, Heinz; Strong, James; Grau, Katrina R; Tibbetts, Scott; Macaulay, Colin; McFadden, Grant; Thoburn, Robert; Lomas, David A; Spinale, Francis G; Virgin, Herbert W; Lucas, Alexandra.

Antimicrob Agents Chemother ; 57(9): 4114-27, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-23774438

5.

A novel strategy to inhibit FAK and IGF-1R decreases growth of pancreatic cancer xenografts.

Zheng, Donghang; Golubovskaya, Vita; Kurenova, Elena; Wood, Cheng; Massoll, Nicole A; Ostrov, David; Cance, William G; Hochwald, Steven N.

Mol Carcinog ; 49(2): 200-9, 2010 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-19885860

6.

Targeting of the protein interaction site between FAK and IGF-1R.

Zheng, Donghang; Kurenova, Elena; Ucar, Deniz; Golubovskaya, Vita; Magis, Andrew; Ostrov, David; Cance, William G; Hochwald, Steven N.

Biochem Biophys Res Commun ; 388(2): 301-5, 2009 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-19664602

7.

Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice.

Yaron, Jordan R; Chen, Hao; Ambadapadi, Sriram; Zhang, Liqiang; Tafoya, Amanda M; Munk, Barbara H; Wakefield, Dara N; Fuentes, Jorge; Marques, Bruno J; Harripersaud, Krishna; Bartee, Mee Yong; Davids, Jennifer A; Zheng, Donghang; Rand, Kenneth; Dixon, Lisa; Moyer, Richard W; Clapp, William L; Lucas, Alexandra R.

J Inflamm (Lond) ; 16: 12, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31160886

8.

Mouse Gamma Herpesvirus MHV-68 Induces Severe Gastrointestinal (GI) Dilatation in Interferon Gamma Receptor-Deficient Mice (IFNÎ³R^-/-) That Is Blocked by Interleukin-10.

Chen, Hao; Bartee, Mee Yong; Yaron, Jordan R; Liu, Liying; Zhang, Liqiang; Zheng, Donghang; Hogue, Ian B; Bullard, Whitney L; Tibbetts, Scott; Lucas, Alexandra R.

Viruses ; 10(10)2018 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-30249047

9.

Selective Deletion of Heparan Sulfotransferase Enzyme, Ndst1, in Donor Endothelial and Myeloid Precursor Cells Significantly Decreases Acute Allograft Rejection.

Chen, Hao; Ambadapadi, Sriram; Wakefield, Dara; Bartee, Meeyong; Yaron, Jordan R; Zhang, Liqiang; Archer-Hartmann, Stephanie A; Azadi, Parastoo; Burgin, Michelle; Borges, Chad; Zheng, Donghang; Ergle, Kevin; Muppala, Vishnu; Morshed, Sufi; Rand, Kenneth; Clapp, William; Proudfoot, Amanda; Lucas, Alexandra.

Sci Rep ; 8(1): 13433, 2018 09 07.

Artigo em Inglês | MEDLINE | ID: mdl-30194334

10.

Atrial Fibrillation Ablation Increases Inflammation-Chemokine Modulation Suppresses Activation of Leukocytes Isolated after Ablation.

Al-Ani, Mohammad; Ambadapadi, Sriram; Yaron, Jordan R; Zheng, Donghang; Fortunel, Adisson; Doroton-Guevara, Maia; Liu, Liying; Morshed, Sufi; Fricker, Jay; Miles, William; McKillop, Matthew; Lucas, Alexandra.

Cardiovasc Hematol Disord Drug Targets ; 17(3): 195-204, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28925907

11.

Polymicrobial Oral Infection with Four Periodontal Bacteria Orchestrates a Distinct Inflammatory Response and Atherosclerosis in ApoE null Mice.

Chukkapalli, Sasanka S; Velsko, Irina M; Rivera-Kweh, Mercedes F; Zheng, Donghang; Lucas, Alexandra R; Kesavalu, Lakshmyya.

PLoS One ; 10(11): e0143291, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26619277

12.

Chronic oral infection with major periodontal bacteria Tannerella forsythia modulates systemic atherosclerosis risk factors and inflammatory markers.

Chukkapalli, Sasanka S; Rivera-Kweh, Mercedes F; Velsko, Irina M; Chen, Hao; Zheng, Donghang; Bhattacharyya, Indraneel; Gangula, Pandu R; Lucas, Alexandra R; Kesavalu, Lakshmyya.

Pathog Dis ; 73(3)2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25663343

13.

Fusobacterium nucleatum Alters Atherosclerosis Risk Factors and Enhances Inflammatory Markers with an Atheroprotective Immune Response in ApoE(null) Mice.

Velsko, Irina M; Chukkapalli, Sasanka S; Rivera-Kweh, Mercedes F; Chen, Hao; Zheng, Donghang; Bhattacharyya, Indraneel; Gangula, Pandu R; Lucas, Alexandra R; Kesavalu, Lakshmyya.

PLoS One ; 10(6): e0129795, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26079509

14.

Serpin treatment suppresses inflammatory vascular lesions in temporal artery implants (TAI) from patients with giant cell arteritis.

Chen, Hao; Zheng, Donghang; Ambadapadi, Sriram; Davids, Jennifer; Ryden, Sally; Samy, Hazem; Bartee, Mee; Sobel, Eric; Dai, Erbin; Liu, Liying; Macaulay, Colin; Yachnis, Anthony; Weyand, Cornelia; Thoburn, Robert; Lucas, Alexandra.

PLoS One ; 10(2): e0115482, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-25658487

15.

Active invasion of oral and aortic tissues by Porphyromonas gingivalis in mice causally links periodontitis and atherosclerosis.

Velsko, Irina M; Chukkapalli, Sasanka S; Rivera, Mercedes F; Lee, Ju-Youn; Chen, Hao; Zheng, Donghang; Bhattacharyya, Indraneel; Gangula, Pandu R; Lucas, Alexandra R; Kesavalu, Lakshmyya.

PLoS One ; 9(5): e97811, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-24836175

16.

Orthotopic kidney transplantation in mice: technique using cuff for renal vein anastomosis.

Chen, Hao; Zhang, Ying; Zheng, Donghang; Praseedom, Raaj Kumar; Dong, Jiahong.

PLoS One ; 8(10): e77278, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24155935

17.

Serpins for diagnosis and therapy in cancer.

Zheng, Donghang; Chen, Hao; Davids, Jennifer; Bryant, Marsha; Lucas, Alexandra.

Cardiovasc Hematol Disord Drug Targets ; 13(2): 123-32, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23988000

18.

Myxomaviral Anti-Inflammatory Serpin Reduces Myeloid-Derived Suppressor Cells and Human Pancreatic Cancer Cell Growth in Mice.

Zheng, Donghang; Chen, Hao; Bartee, Mee Y; Williams, Jennifer; Davids, Jennifer A; Lomas, David A; McFadden, Grant; Lucas, Alexandra R.

J Cancer Sci Ther ; 5: 291-299, 2013 Aug 19.

Artigo em Inglês | MEDLINE | ID: mdl-25798214

19.

The serpin solution; targeting thrombotic and thrombolytic serine proteases in inflammation.

Chen, Hao; Davids, Jennifer A; Zheng, Donghang; Bryant, Marsha; Bot, Ilze; van Berckel, Theo J C; Biessen, Erik; Pepine, Carl; Ryman, Kate; Progulski-Fox, Ann; Kesavalu, Lakshmyya; Moyer, Richard; McFadden, Grant; Lucas, Alexandra.

Cardiovasc Hematol Disord Drug Targets ; 13(2): 99-110, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23987998

20.

SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats.

Hatch, Heather M; Zheng, Donghang; Jorgensen, Marda L; Petersen, Bryon E.

Cloning Stem Cells ; 4(4): 339-51, 2002.

Artigo em Inglês | MEDLINE | ID: mdl-12626097

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