Pesquisa | Portal de Pesquisa da BVS

1.

Identification of osteolineage cell-derived extracellular vesicle cargo implicated in hematopoietic support.

Morhayim, Jess; Ghebes, Corina A; Erkeland, Stefan J; Ter Borg, Mariëtte N D; Hoogenboezem, Remco M; Bindels, Eric M J; van Alphen, Floris P J; Kassem, Moustapha; van Wijnen, Andre J; Cornelissen, Jan J; van Leeuwen, Johannes P; van der Eerden, Bram C J; Voermans, Carlijn; van de Peppel, Jeroen; Braakman, Eric.

FASEB J ; 34(4): 5435-5452, 2020 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-32086861

2.

Two-day-treatment of Activin-A leads to transient change in SV-HFO osteoblast gene expression and reduction in matrix mineralization.

Baroncelli, Marta; Drabek, Ksenija; Eijken, Marco; van der Eerden, Bram C J; van de Peppel, Jeroen; van Leeuwen, Johannes P T M.

J Cell Physiol ; 235(5): 4865-4877, 2020 May.

Artigo em Inglês | MEDLINE | ID: mdl-31667867

3.

A follistatin-based molecule increases muscle and bone mass without affecting the red blood cell count in mice.

Lodberg, Andreas; van der Eerden, Bram C J; Boers-Sijmons, Bianca; Thomsen, Jesper Skovhus; Brüel, Annemarie; van Leeuwen, Johannes P T M; Eijken, Marco.

FASEB J ; 33(5): 6001-6010, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30759349

4.

Human mesenchymal stromal cells in adhesion to cell-derived extracellular matrix and titanium: Comparative kinome profile analysis.

Baroncelli, Marta; Fuhler, Gwenny M; van de Peppel, Jeroen; Zambuzzi, Willian F; van Leeuwen, Johannes P; van der Eerden, Bram C J; Peppelenbosch, Maikel P.

J Cell Physiol ; 234(3): 2984-2996, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30058720

5.

Hydroxychloroquine decreases human MSC-derived osteoblast differentiation and mineralization in vitro.

Both, Tim; van de Peppel, H Jeroen; Zillikens, M Carola; Koedam, Marijke; van Leeuwen, Johannes P T M; van Hagen, P Martin; van Daele, Paul L A; van der Eerden, Bram C J.

J Cell Mol Med ; 22(2): 873-882, 2018 02.

Artigo em Inglês | MEDLINE | ID: mdl-28975700

6.

Comparative proteomic profiling of human osteoblast-derived extracellular matrices identifies proteins involved in mesenchymal stromal cell osteogenic differentiation and mineralization.

Baroncelli, Marta; van der Eerden, Bram C; Kan, Yik-Yang; Alves, Rodrigo D; Demmers, Jeroen A; van de Peppel, Jeroen; van Leeuwen, Johannes P.

J Cell Physiol ; 233(1): 387-395, 2018 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-28272740

7.

Hydroxychloroquine affects bone resorption both in vitro and in vivo.

Both, Tim; Zillikens, M Carola; Schreuders-Koedam, Marijke; Vis, Marijn; Lam, Wai-Kwan; Weel, Angelique E A M; van Leeuwen, Johannes P T M; van Hagen, P Martin; van der Eerden, Bram C J; van Daele, Paul L A.

J Cell Physiol ; 233(2): 1424-1433, 2018 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-28556961

8.

Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway.

Brum, Andrea M; van de Peppel, Jeroen; van der Leije, Cindy S; Schreuders-Koedam, Marijke; Eijken, Marco; van der Eerden, Bram C J; van Leeuwen, Johannes P T M.

Proc Natl Acad Sci U S A ; 112(41): 12711-6, 2015 Oct 13.

Artigo em Inglês | MEDLINE | ID: mdl-26420877

9.

Immunotherapy Added to Antibiotic Treatment Reduces Relapse of Disease in a Mouse Model of Tuberculosis.

Mourik, Bas C; Leenen, Pieter J M; de Knegt, Gerjo J; Huizinga, Ruth; van der Eerden, Bram C J; Wang, Jinshan; Krois, Charles R; Napoli, Joseph L; Bakker-Woudenberg, Irma A J M; de Steenwinkel, Jurriaan E M.

Am J Respir Cell Mol Biol ; 56(2): 233-241, 2017 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-27654457

10.

Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.

Kemp, John P; Medina-Gomez, Carolina; Estrada, Karol; St Pourcain, Beate; Heppe, Denise H M; Warrington, Nicole M; Oei, Ling; Ring, Susan M; Kruithof, Claudia J; Timpson, Nicholas J; Wolber, Lisa E; Reppe, Sjur; Gautvik, Kaare; Grundberg, Elin; Ge, Bing; van der Eerden, Bram; van de Peppel, Jeroen; Hibbs, Matthew A; Ackert-Bicknell, Cheryl L; Choi, Kwangbom; Koller, Daniel L; Econs, Michael J; Williams, Frances M K; Foroud, Tatiana; Zillikens, M Carola; Ohlsson, Claes; Hofman, Albert; Uitterlinden, André G; Davey Smith, George; Jaddoe, Vincent W V; Tobias, Jonathan H; Rivadeneira, Fernando; Evans, David M.

PLoS Genet ; 10(6): e1004423, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24945404

11.

Novel Compound Heterozygous Mutations in the CYP27B1 Gene Lead to Pseudovitamin D-Deficient Rickets.

Koek, W Nadia H; Zillikens, M Carola; van der Eerden, Bram C J; van Leeuwen, Johannes P T M.

Calcif Tissue Int ; 99(3): 326-31, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27364341

12.

MicroRNAs in the skeleton: cell-restricted or potent intercellular communicators?

van der Eerden, Bram C J.

Arch Biochem Biophys ; 561: 46-55, 2014 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-24832391

13.

The vitamin D analog ZK191784 normalizes decreased bone matrix mineralization in mice lacking the calcium channel TRPV5.

van der Eerden, Bram C J; Fratzl-Zelman, Nadja; Nijenhuis, Tom; Roschger, Paul; Zügel, Ulrich; Steinmeyer, Andreas; Hoenderop, Joost G J; Bindels, René J M; Klaushofer, Klaus; van Leeuwen, Johannes P T M.

J Cell Physiol ; 228(2): 402-7, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22740316

14.

The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice.

van der Eerden, Bram C J; Weissgerber, Petra; Fratzl-Zelman, Nadja; Olausson, Jenny; Hoenderop, Joost G J; Schreuders-Koedam, Marijke; Eijken, Marco; Roschger, Paul; de Vries, Teun J; Chiba, Hideki; Klaushofer, Klaus; Flockerzi, Veit; Bindels, René J M; Freichel, Marc; van Leeuwen, Johannes P T M.

J Cell Physiol ; 227(5): 1951-9, 2012 May.

Artigo em Inglês | MEDLINE | ID: mdl-21732366

15.

Characterization of vitamin D-deficient klotho(-/-) mice: do increased levels of serum 1,25(OH)2D3 cause disturbed calcium and phosphate homeostasis in klotho(-/-) mice?

Woudenberg-Vrenken, Titia E; van der Eerden, Bram C J; van der Kemp, AnneMiete W C M; van Leeuwen, Johannes P T M; Bindels, René J M; Hoenderop, Joost G J.

Nephrol Dial Transplant ; 27(11): 4061-8, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22778178

16.

Unraveling the human bone microenvironment beyond the classical extracellular matrix proteins: a human bone protein library.

Alves, Rodrigo D A M; Demmers, Jeroen A A; Bezstarosti, Karel; van der Eerden, Bram C J; Verhaar, Jan A N; Eijken, Marco; van Leeuwen, Johannes P T M.

J Proteome Res ; 10(10): 4725-33, 2011 Oct 07.

Artigo em Inglês | MEDLINE | ID: mdl-21892838

17.

Upstream Regulators of Fibroblast Growth Factor 23.

Ratsma, Danielle M A; Zillikens, M Carola; van der Eerden, Bram C J.

Front Endocrinol (Lausanne) ; 12: 588096, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33716961

18.

Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.

Franken, Gijs A C; Seker, Murat; Bos, Caro; Siemons, Laura A H; van der Eerden, Bram C J; Christ, Annabel; Hoenderop, Joost G J; Bindels, René J M; Müller, Dominik; Breiderhoff, Tilman; de Baaij, Jeroen H F.

Sci Rep ; 11(1): 8217, 2021 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-33859252

19.

Klotho prevents renal calcium loss.

Alexander, R Todd; Woudenberg-Vrenken, Titia E; Buurman, Jan; Dijkman, Henry; van der Eerden, Bram C J; van Leeuwen, Johannes P T M; Bindels, René J; Hoenderop, Joost G.

J Am Soc Nephrol ; 20(11): 2371-9, 2009 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-19713312

20.

Activin type IIA decoy receptor and intermittent parathyroid hormone in combination overturns the bone loss in disuse-osteopenic mice.

Brent, Mikkel Bo; Lodberg, Andreas; Bromer, Frederik Duch; van der Eerden, Bram C J; Eijken, Marco; Brüel, Annemarie; Thomsen, Jesper Skovhus.

Bone ; 142: 115692, 2020 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-33069923

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