Dental management of a pediatric patient with progressive familial intrahepatic cholestasis having dental anomalies: a case report and brief review of the literature.

BACKGROUND: Progressive familial intrahepatic cholestasis is a heterogeneous group of disorders, leading to intrahepatic cholestasis, with the possibility of chronic liver failure and biliary cirrhosis. Oligodontia is either the manifestation of a specific syndrome or is non-syndromic. To the best of our knowledge, this is the first case report of type 3 progressive familial intrahepatic cholestasis and concurrent oligodontia, craniosynostosis, dens in dente, taurodontism, and delayed permanent dentition in the medical and dental literature. CASE PRESENTATION: We present the dental and medical histories and comprehensive dental management of a girl with type 3 progressive familial intrahepatic cholestasis and several dental anomalies, who was referred to a dental clinic due to severe dental caries and pain. CONCLUSION: Our findings suggest that PFIC with manifestations as oligodontia, craniosynostosis, dens in dente, taurodontism, and delayed permanent dentition, might indicate an unknown syndrome; otherwise, the craniofacial anomalies are the manifestations of an independent disease coinciding with PFIC. Moreover, our case is a good example of the importance of timely medical and dental care in confining further health-related complications. The patient was able to ingest without any pain or discomfort after receiving proper dental management.

Nonsurgical management of type II dens invaginatus with cone beam computed tomography: A rare case.

Dens invaginatus is a progressive abnormality resulting from invagination of the crown or root before calcification. This case report presents nonsurgical endodontic treatment and nine-year follow-up results of a right maxillary canine tooth with type II dens invaginatus. A 40-year-old female patient was referred to the clinic for treatment of her maxillary right canine tooth. The invagination was managed on a two-visit appointment. On the first visit, the invagination area, which was disconnected, was completely removed from the root canal. The invagination area was instrumented, and the root canal was dressed with calcium hydroxide. At the second appointment, apexification was done using mineral trioxide aggregate compacted to the apical 3mm. Finally, the invaginated area and the root canal were obturated with a warm vertical compaction technique. At a nine-year follow-up, the invaginated tooth was asymptomatic, and the periradicular lesion showed satisfactory healing radiographically.

Cone-beam computed tomography for assessment of dens invaginatus in the Polish population.

OBJECTIVES: There are many developmental variations in the permanent dentition. Dens invaginatus can be recognized on many dental X-rays of affected patients, but not every image allows for assessment of the type of malformation. The aim of the present study was to assess the presence of dens invaginatus with radiological features using cone-beam computed tomography (CBCT). METHODS: CBCT images of 33 patients were evaluated. Age, sex, side, lateralization, occurrence in a particular group of teeth, type of invagination, differentiation, and the consequences of these factors were analyzed. RESULTS: Forty-one teeth with dens invaginatus met the inclusion criteria for this evaluation. Females were affected more frequently than males (57.6 vs. 42.4%, respectively). The patients' age ranged from 7 to 40 years, and the occurrence of dens invaginatus peaked from age 9 to 13 years. In total, 92.7% of affected teeth were present in the maxilla, more often unilaterally (75.8%) than bilaterally (24.2%). The most frequent tooth with dens invaginatus was the maxillary lateral incisor (53.7% of affected teeth). Almost two-thirds (63.4%) of affected teeth were found on the left side and 36.6% were found on the right. The tooth anatomy was distorted within the crown and root. Dens invaginatus sometimes affected other surrounding teeth and reduced their esthetics. CONCLUSIONS: The obtained data indicate that CBCT examination is an essential tool in assessing dens invaginatus and can guide dental practitioners in treating patients who exhibit characteristic features of this disorder. CBCT allows the clinician to distinguish the type of anomaly.

Dens invagination and root dilaceration in double multilobed mesiodentes in 14-year-old patient with anorexia nervosa.

This paper describes a rare case of erupted double supernumerary teeth with unusual morphology in a 14-year-old patient with an eating disorder. The coexistence of dental morphological anomalies: multilobed mesiodens, multiple dens in dente of different types and root dilaceration have not been previously reported. The paper highlights anatomical and radiological aspects of dental abnormalities and clinical implications of delayed treatment.

Endodontic management of a double-type IIIB dens invaginatus in a vital maxillary central incisor aided by CBCT: A case report.

Type IIIB dens invaginatus presents with diagnostic and treatment related challenges when in need of endodontic management as a consequence of its complex anatomy, especially when presented in a vital tooth with a periapical lesion. Apical periodontitis associated with two type IIIB invaginations in a central maxillary incisor of a 10-year-old patient was diagnosed. A cone-beam computed tomography (CBCT) scan provided essential diagnostic information and steered the treatment plan. The two invaginations were separate, with no communication between them and the pulp. The pulp appeared vital and non-inflamed. Endodontic treatment of the invaginations was carried out without intervention in the pulp. A 4-month follow-up periapical radiograph showed significant shrinkage of the lesion and a 2-year follow-up CBCT scan confirmed its complete healing. The pulp remains vital, responding normally to sensitivity tests. This outcome indicates that preserving the pulp's vitality is achievable through timely diagnosis.

Rare variant of dens invaginatus with accessory root and labial talon cusp in maxillary lateral incisor-Case report.

Dens invaginatus (DI) often causes dysmorphic changes in both the crown and root. This case report presents a complicated type 3a DI in a maxillary lateral incisor with labial talon cusp and root bifurcation. Although lingual talon cusp is common in maxillary lateral incisor, labial talon cusp is rare. An auxiliary palatal root in maxillary lateral incisor is also unusual. No such case involving all three variations has been described in the literature. The DI was classified as type B4 according to Schulze and Brand, as it involved division of pulp and root. DI was managed by orthograde MTA, radisectomy and periodontal regeneration was done for the palatal root. Labial talon associated with DI and can lead to early periodontal/pulpal involvement. Type 3 DI can affect the root with marked dilatation and division. Additional palatal root should be carefully detected in type 3a DI and managed with the aid of CBCT.

Endodontic management of type IIIb dens invaginatus in central incisor: A case report.

We described a type IIIb dens invaginatus, its root canal treatment, and results on 3- and 12-month visits. Despite its significant challenges, proper endodontic therapy in such cases can cause positive prognosis and successful outcome.

Conservative management of dens in dente.

Dens Invaginatus (DI) or dens in dente is an uncommon anomaly which mostly affects permanent lateral incisors, and it is very rare in molars. This article presents the conservative endodontic management of four different cases of DI and a discussion of the endodontic literature for this malformation. Three upper lateral incisors Type II, IIIa and IIIb, and an upper first molar Type II are shown. The most conservative approach possible was carried out. Three of the cases were obturated using the continuous wave technique. In one of the cases, it was possible to treat only the invagination with MTA and preserve the pulp vitality of the main canal. To make a correct diagnosis and to treat in the most conservative way possible, a DI is necessary to know its classification and use tools such as CBCT and magnification.

Prevalence and morphological analysis of dens invaginatus in anterior teeth using cone beam computed tomography: A systematic review and meta-analysis.

OBJECTIVES: To evaluate the prevalence and morphological characteristics of DI using CBCT. METHODS: A literature search was performed in PubMed, Embase, Scopus, and Web of Science. Inclusion criteria were randomized clinical trials, cross-sectional studies, and prospective and retrospective cohort studies evaluating the morphological characteristics of DI in anterior teeth using CBCT. Three reviewer authors independently screened the studies, applied the eligibility criteria, assessed the risk of bias, and extracted until September (2022). The risk of bias was evaluated using the Joanna Briggs Institute criteria. Meta-analyses of proportions were used for estimate the prevalence DI according to factors at participant and tooth levels. RESULTS: Six studies were included in the meta-analysis. Among 7373 individuals, a prevalence of 7.45 % of DI was observed (n = 258; τ2 = 0.0096; CI of 4.51-11.3; p < 0.05), with no significant influence of sex. Regarding laterality, unilateral DI showed higher mean prevalence (4.30 %; CI of 2.03-7.33). Among the 382 anterior teeth with DI (0.72 %), the most affected tooth was the upper lateral incisor (5.12 %; n = 329; CI of 2.35-8.86; p < 0.001), type I was the most prevalent (0.59 %; CI of 0.24-1.08) and the presence of open apex and periradicular pathology ranged from 4.3 % to 22.72 % and 3.5-77.92 %, respectively. CONCLUSIONS: The prevalence of individuals with dens invaginatus was 7.45 %, the most affect tooth was the upper lateral incisor with a prevalence of 5.12 % unilaterally and type I was the most prevalent morphology.

Radicular variant of dens in dente (RDinD) in a patient undergoing radioisotope therapy.

Dense in dente is a developmental anomaly frequently encountered in permanent maxillary incisors, with a prevalence rate of 0.25-10%. Our review of the scientific literature on a radicular variant of dens in dente (RDinD) in permanent molar teeth identified only two reported cases with a confirmed diagnosis. Here, we report the third case of RDinD, in a 37-year-old woman presenting with nocturnal pain in the left maxillary second molar for 1 week. The patient had a medical history of surgery for papillary thyroid carcinoma followed by radioactive iodine therapy. We established a diagnosis of RDinD with an osteolytic lesion and transverse fracture line along the palatal root of the tooth by using cone beam computed tomography (CBCT). Extraction and periapical curettage of the lesion were performed, and the patient was followed up. In summary, we observed a rare clinical presentation of RDinD in the left maxillary second molar of a 37-year-old female patient.

Regenerative endodontic treatment of dens in dente in maxillary lateral incisor with immature root: a case report.

Dens invaginatus (DI) is a developmental anomaly as a result of a deepening or invagination of the enamel organ into the dental papilla during tooth development. In addition, DI is a malformation with varying anatomical features, which poses numerous challenges to treatment. Endodontic treatment of dens in dente is one of the most complica-ted cases of DI. Herein, an immature lateral incisor that employed regenerative endodontic treatment was presented. The mentioned tooth was diagnosed with DI, pulp necrosis, and chronic apical periodontitis. Hence, a favorable prognosis has been shown by a 2-year review with cone beam computed tomography. The tooth was functional with normal periodontal parameters and exhibited a normal response to the electric pulp sensibility test. Thus, regenerative endodontic treatment can also be recommended to endodontists for teeth with DI.

Surgical Treatment of a Dens Invagination Type (І) in a Maxillary Lateral Incisor with 6-Year Follow-Up.

Dens invagination is a developmental anomaly that requires specific treatment approaches. The invagination is enamel-lined in the crown of the tooth truly negligible, and usually there is no extension on the level of the external amelocemental junction. A well ending surgical root canal treatment of an invaginated tooth with a retrograde filling is presented in this case report. Periapical radiographic examination, after 3 months and 6 years of follow-up, showed periapical healing with osseous formation .

[Dens invaginatus or dilated odontoma, a definition controversy.] / Dens invaginatus u odontoma dilatado, controversia de una definición.

The invaginate tooth (IT) is an alteration in the development of the dental organ, which occurs as a consequence of invagination of the internal epithelium of the enamel organ. IT is also known as "dens in dente", among other denominations, and presents a series of clinical, histological and imaging characteristics. The most extreme variant of IT has a very complex configuration, and the magnitude of the intussusception has led to it also being called dilated odontoma, being a term that generates confusion in some professionals.While the term odontoma has been reported as a synonym for both IT as well as a new variant of odontomas, there is a difference betweene the two types: one is a developmental anomaly and the other is a growth with a hamartomatous appearance. However, the literature continues to use both terms to define IT, and thus, it is important to know the origin and be aware that the controversy is based on historical and customary references.

Endodontic Management of a Maxillary Lateral Incisor with Dens Invagination and Periapical Lesion: A Case Report and Mini Review of the Literature.

Dens invagination (DI) is a dental anomaly that can cause pulpal and periapical pathoses of the affected tooth. We describe the treatment of a healthy 18-year-old female with a chief complaint of recurrent facial swelling pertaining to a peg-shaped maxillary lateral incisor with DI. Examinations showed necrosis of the involved tooth with symptomatic apical periodontitis. Cone-beam computed tomography corresponded to Oehlers type II DI. Orthograde endodontic treatment was performed. To completely debride the canal and resolve the persistent purulent discharge, various methods and medicaments were used in separate sessions including passive ultrasonic activation of 5.25% sodium hypochlorite solution, calcium hydroxide mixed with 2% chlorhexidine, and double antibiotic paste as intracanal medicament. After resolution of the symptoms, the root canal and the invaginated space were filled by a mineral trioxide aggregate plug and backfilled with thermoplasticized gutta-percha. At the one-year follow-up, complete bone healing was noted in the affected periradicular area.

Influence of cooking duration on carotenoids, physical properties and in vitro antioxidant capacity of pasta prepared from three Canadian durum wheat cultivars.

This study investigates the impact of different pasta cooking durations (al dente, fully cooked or overcooked) on the carotenoid content and physical properties of whole wheat and refined semolina pasta prepared from three Canadian durum wheat cultivars. Carotenoids were analyzed using HPLC and spectrophotometry. Generally increasing cooking duration non-significantly increased lutein, zeaxanthin, total carotenoids, significantly increased the cis carotenoids but decreased carotenoid retention and firmness regardless of flour type or wheat cultivar. Despite this decrease, whole wheat pasta was significantly firmer than semolina when overcooked regardless of wheat cultivar. Antioxidant capacity was highly influenced by flour type but did not show a clear trend with cooking duration. Overall analysis indicates that increasing cooking duration of whole wheat or semolina pasta above 7 or 8 mins respectively allows for the maximum extraction of carotenoids with possible accessibility by digestive enzymes when consumed but this affects cooking quality including high cooking loss.

A Rare Case of Radicular Dens Invaginatus (Dens in Dente) in a Dog.

A rare case of radicular dens invaginatus (dens in dente) was found during dental cleaning of a 5-year-old male Rottweiler dog. Radiographic examination revealed intense radiopacity, which extended from the crown to the apical root region of the affected tooth. Macroscopically, the crown of the left maxillary first molar tooth (209) had irregular and deformed buccal and lingual surfaces. Microscopic examination revealed dentine invagination in the pulp cavity in of the crown and root and pulp necrosis. Based on the gross, radiographic and histological findings, a diagnosis of radicular dens invaginatus was made.

A Variant of the Current Dens Invaginatus Classification.

Endodontic treatment of maxillary incisors may be considered straight forward. However, in some instances, they may exhibit aberrant morphology. One of these rare variations in tooth morphology is dens invaginatus. To improve the endodontic prognosis of such teeth, a detailed evaluation of the tooth under treatment is important, which requires comprehensive clinical and radiographic examinations, including periapical radiography and cone-beam computed tomography (CBCT), which is highly recommended whenever atypical root canal morphology is suspected on a periapical radiograph. The current case report discusses the diagnosis of type IV dens invaginatus in a maxillary lateral incisor using CBCT.

Coronectomia como técnica alternativa à exodontia de terceiros molares impactados com risco de lesão ao nervo alveolar inferior / Coronectomy as an alternative technique to the extraction of impacted third molars with risk of injury to the inferior alveolar nerve

A coronectomia consiste no procedimento em que se faz a remoção da coroa do dente deixando a raiz in situ. Tal técnica é indicada para dentes posteriores impactados que apresentem proximidade com o canal mandibular representando assim um risco ao nervo mandibular caso seja feita uma exodontia. O seguinte trabalho tem como objetivo demonstrar os aspectos positivos relacionados ao emprego da técnica de coronectomia para dentes posteriores impactados. Foram realizadas buscas bibliográficas nas bases de dados PUBMED, MEDLINE e sciELO usando os descritores "coronectomia", "coronectomy", "terceiros molares impactados", "trigeminal", "nerve damage", respeitando critérios de relevância quanto ao tema foram selecionados 31 artigos. Sabe-se que pelo canal mandibular passa o nervo alveolar inferior e esse é responsável pela inervação sensitiva de estruturas anatômicas importantes, logo dentes impactados que tenham grande proximidade com o canal mandibular quando empregadas técnicas de exodontia correm o risco de lesionar o nervo podendo gerar perda da sensibilidade de forma passageira ou permanente, a indicação para realização da técnica precisa ser feita posteriormente à análise radiográfica e tomográfica da relação do dente com o canal mandibular. A técnica consiste na remoção da coroa do dente e o suficiente da raiz abaixo da crista vestibular e lingual do osso, para que esse possa desencadear um processo de cicatrização natural sobre as raízes retidas. Conclui-se que a coronectomia é um procedimento alternativo seguro e eficaz para casos específicos que se tem indicação e apresenta prognóstico favorável.

The coronectomy consists of the procedure in which the crown of the tooth is removed leaving the root in situ. This technique is indicated for impacted posterior teeth in close proximity to the mandibular canal representing a risk to the mandibular nerve if an extraction is performed. The following study has the porpouse to demonstrate the positive aspects related to the use of the coronectomy technique for impacted posterior teeth. Bibliographic searches were carried out in the databases PUBMED, MEDLINE, sciELO, using the DeCS "coronectomy", "odontectomy", "trigeminal", "nerve damage", respecting the criterion of relevance to the topic, 31 articles were selected. It is known that the inferior alveolar nerve passes through the mandibular canal and is responsible for the sensitive innervation of important anatomical structures, so impacted teeth that are very close to the mandibular canal when extraction techniques are used has the risk of injuring the nerve, which may lead to temporary or permanent loss of sensitivity, the indication for performing the technique needs to be made after the radiographic and tomographic analysis of the affinity between the tooth and the mandibular canal. The technique consists of removing the crown of the tooth and enough of the root below the buccal and lingual crest of the bone, so that it can trigger a natural healing process on the retained roots. It is concluded that coronectomy is a safe and effective alternative procedure for specific cases that are indicated and have a favorable prognosis.

Black male, 19: Brazilian "criminal commando" and the breach of human rights / Homem negro, 19 anos: o "comando criminoso" brasileiro e a violação dos direitos humanos

Dental age estimation is a technical procedure performed to support Court decisions in cases of legal liability, clandestine migration, sexual abuse, and several other applications. This study reports a case of an undocumented individuals that was originally identified by the criminal legal system (without a previous civil identity). In his identity records, a name was given: "Black male, 19" ­ indicating his population affinity (African), sex (male) and age (19 years). His body was found decapitated and referred to the medicolegal institute. The dental examination highlighted the presence of a third molar in the very early stage (») of root formation. Age was estimated using five methods based on dental development (the methods of Schour and Massler [1941], Moorrees et al. [1963], Anderson et al. [1976], London Atlas [2010], and Blenkin and Taylor [2012]). All the methods indicated that the individual was a minor, within the range between 14.5 and 15.5 years. This study highlights the importance of assigning adequate personnel to technical tasks in the police/forensic routine in order to safeguard human rights

A estimativa da idade dentária é um procedimento técnico realizado para apoiar decisões judiciais em casos de responsabilidade legal, migração clandestina, abuso sexual e diversas outras aplicações. Este estudo relata o caso de um indivíduo indocumentado que foi originalmente identificado pelo sistema penal (sem identidade civil prévia). Nos seus registos de identidade foi atribuído um nome: "Homem negro, 19 anos" ­ indicando a sua afinidade populacional (africana), sexo (masculino) e idade (19 anos). Seu corpo foi encontrado decapitado e encaminhado a um Instituto Médico-legal. O exame odontológico evidenciou a presença de um terceiro molar em fase muito inicial (») de formação radicular. A idade foi estimada usando cinco métodos baseados no desenvolvimento dentário (os métodos de Schour e Massler [1941], Moorrees et al. [1963], Anderson et al. [1976], London Atlas [2010] e Blenkin e Taylor [2012]). Todos os métodos indicaram que o indivíduo era menor de idade, na faixa entre 14,5 e 15,5 anos. Este estudo destaca a importância de designar pessoal adequado para tarefas técnicas na rotina policial/forense, a fim de salvaguardar os direitos humanos

Percepção dos pais sobre os sinais e sintomas decorrentes da erupção dentária em bebês / Parents' perception about tooth eruption signs and symptoms in babies

A erupção dentária é definida como a movimentação dos dentes em desenvolvimento para emergir através dos tecidos moles da maxila e da mandíbula. O primeiro dente decíduo geralmente irrompe na cavidade bucal em um intervalo entre quatro e dez meses de idade e manifestações locais e sistêmicas associadas à erupção são observadas e relatadas por pais de bebês que passam pelo processo. Deste modo, este trabalho busca revisar e analisar a literatura em relação à percepção dos pais sobre os sinais e sintomas observados durante o processo de erupção dentária em bebês. Foi realizada uma revisão integrativa da literatura, buscando por artigos indexados nas bases eletrônicas de dados PubMed e Portal BVS. Ao final, foram selecionados 16 artigos científicos, sendo em sua maioria estudos com delineamento transversal (n: 11). Apenas dois estudos foram realizados no Brasil, sendo a Índia (n: 4) o país com maior número de artigos incluídos. Os sinais e sintomas mais relatados pelos pais foram febre (n: 16), perda de apetite (n: 13) e aumento da salivação (n: 12). Os estudos analisados apresentaram limitações, como a falta de padronização dos questionários direcionados aos pais. Compreende-se, desta forma, que mais estudos com populações variadas, amostras maiores e questionários padronizados são necessários.

Dental eruption is defined as the movement of developing teeth to emerge through the soft tissues of the maxilla and mandible. The first deciduous tooth usually erupts into the oral cavity between the fourth and tenth month of age. During this time, local and systemic manifestations are observed and reported by parents of babies who undergo the process. Thus, this stud seeks to review and analyze the literature regarding the perception of parents about the signs and symptoms observed during the process of tooth eruption in babies. An integrative literature review was performed, searching for articles indexed in PubMed and Portal BVS electronic databases. Sixteen papers were selected, mostly of which were cross-sectional studies (n: 11). Only two studies were carried out in Brazil, with India (n: 4) being the country with the highest number of articles included. The most reported signs and symptoms were fever (n: 16), loss of appetite (n: 13) and increased salivation (n: 12). The analyzed studies had limitations, such as the lack of standardization of the questionnaires addressed to parents. We conclude more studies with varied populations, larger samples and standardized questionnaires are needed.