Label-Free DNA Hybridization Detection Using a Highly Sensitive Fiber Microcavity Biosensor.

A novel label-free optical fiber biosensor, based on a microcavity fiber Mach-Zehnder interferometer, was developed and practically demonstrated for DNA detection. The biosensor was fabricated using offset splicing standard communication single-mode fibers (SMFs). The light path of the sensor was influenced by the liquid sample in the offset open cavity. In the experiment, a high sensitivity of -17,905 nm/RIU was achieved in the refractive index (RI) measurement. On this basis, the probe DNA (pDNA) was immobilized onto the sensor's surface using APTES, enabling real-time monitoring of captured complementary DNA (cDNA) samples. The experimental results demonstrate that the biosensor exhibited a high sensitivity of 0.32 nm/fM and a limit of detection of 48.9 aM. Meanwhile, the sensor has highly repeatable and specific performance. This work reports an easy-to-manufacture, ultrasensitive, and label-free DNA biosensor, which has significant potential applications in medical diagnostics, bioengineering, gene identification, environmental science, and other biological fields.

Experimental Study of White Light Interferometry in Mach-Zehnder Interferometers Based on Standard Single Mode Fiber.

In this work, we experimentally analyzed and demonstrated the performance of an in-line Mach-Zehnder interferometer in the visible region, with an LED light source. The different waist diameter taper and asymmetric core-offset interferometers proposed used a single-mode fiber (SMF). The visibility achieved was V = 0.14 with an FSR of 23 nm for the taper MZI structure and visibilities of V = 0.3, V = 0.27, and V = 0.34 with FSRs of 23 nm, 17 nm, and 8 nm and separation lengths L of 2.5 cm, 4.0 cm, and 5.0 cm between the core-offset structure, respectively. The experimental investigation of the response to the temperature sensor yielded values from 50 °C to 300 °C; the sensitivity obtained was 3.53 a.u./°C, with R2 of 0.99769 and 1% every 1 °C in the transmission. For a range of 50 °C to 150 °C, 20.3 pm/°C with a R2 of 0.96604 was obtained.

The Highly Sensitive Refractive Index Sensing of Seawater Based on a Large Lateral Offset Mach-Zehnder Interferometer.

A novel fiber sensor for the refractive index sensing of seawater based on a Mach-Zehnder interferometer has been demonstrated. The sensor consisted of a single-mode fiber (SMF)-no-core fiber (NCF)-single-mode fiber structure (shortened to an SNS structure) with a large lateral offset spliced between the two sections of a multimode fiber (MMF). Optimization studies of the multimode fiber length, offset SNS length, and vertical axial offset distance were performed to improve the coupling efficiency of interference light and achieve the best extinction ratio. In the experiment, a large lateral offset sensor was prepared to detect the refractive index of various ratios of saltwater, which were used to simulate seawater environments. The sensor's sensitivity was up to -13,703.63 nm/RIU and -13,160 nm/RIU in the refractive index range of 1.3370 to 1.3410 based on the shift of the interference spectrum. Moreover, the sensor showed a good linear response and high stability, with an RSD of only 0.0089% for the trough of the interference in air over 1 h.

Directional Torsion Sensor Based on a Two-Core Fiber with a Helical Structure.

A fiber-optic torsion sensor based on a helical two-core fiber (HTCF) is proposed and experimentally demonstrated for simultaneously measuring torsion angle and torsion direction. The sensor consists of a segment of HTCF and two single-mode fibers (SMFs) forming a Mach-Zehnder interferometer (MZI). The helical structure is implemented by pre-twisting a 1 cm long two-core fiber (TCF). The performance of the sensor with pre-twisted angles of 180°, 360°, and 540° is experimentally analyzed. The results show that the sensor can realize the angular measurement and effectively distinguish the torsion direction. It is worth noting that the sensor has maximum sensitivity when the pre-twist angle is 180 degrees. The obtained wavelength sensitivities of torsion and temperature are 0.242 nm/(rad/m) and 32 pm/°C, respectively. The sensor has the advantages of easy fabrication, low cost, compact structure, and high sensitivity, which is expected to yield potential applications in fields where both torsion angle and direction measurements are required.

Synchronous Phase-Shifting Interference for High Precision Phase Imaging of Objects Using Common Optics.

Quantitative phase imaging and measurement of surface topography and fluid dynamics for objects, especially for moving objects, is critical in various fields. Although effective, existing synchronous phase-shifting methods may introduce additional phase changes in the light field due to differences in optical paths or need specific optics to implement synchronous phase-shifting, such as the beamsplitter with additional anti-reflective coating and a micro-polarizer array. Therefore, we propose a synchronous phase-shifting method based on the Mach-Zehnder interferometer to tackle these issues in existing methods. The proposed method uses common optics to simultaneously acquire four phase-shifted digital holograms with equal optical paths for object and reference waves. Therefore, it can be used to reconstruct the phase distribution of static and dynamic objects with high precision and high resolution. In the experiment, the theoretical resolution of the proposed system was 1.064 µm while the actual resolution could achieve 1.381 µm, which was confirmed by measuring a phase-only resolution chart. Besides, the dynamic phase imaging of a moving standard object was completed to verify the proposed system's effectiveness. The experimental results show that our proposed method is suitable and promising in dynamic phase imaging and measurement of moving objects using phase-shifting digital holography.

Prototype Optical Bionic Microphone with a Dual-Channel Mach-Zehnder Interferometric Transducer.

A prototype optical bionic microphone with a dual-channel Mach-Zehnder interferometric (MZI) transducer was designed and prepared for the first time using a silicon diaphragm made by microelectromechanical system (MEMS) technology. The MEMS diaphragm mimicked the structure of the fly Ormia Ochracea's coupling eardrum, consisting of two square wings connected through a neck that is anchored via the two torsional beams to the silicon pedestal. The vibrational displacement of each wing at its distal edge relative to the silicon pedestal is detected with one channel of the dual-channel MZI transducer. The diaphragm at rest is coplanar with the silicon pedestal, resulting in an initial phase difference of zero for each channel of the dual-channel MZI transducer and consequently offering the microphone strong temperature robustness. The two channels of the prototype microphone show good consistency in their responses to incident sound signals; they have the rocking and bending resonance frequencies of 482 Hz and 1911 Hz, and their pressure sensitivities at a lower frequency exhibit an "8"-shaped directional dependence. The comparison indicates that the dual-channel MZI transducer-based bionic microphone proposed in this work is advantageous over the Fabry-Perot interferometric transducer-based counterparts extensively reported.

Advances in Multicore Fiber Interferometric Sensors.

In this paper, a review of multicore fiber interferometric sensors is given. Due to the specificity of fiber structure, i.e., multiple cores integrated into only one fiber cladding, multicore fiber (MCF) interferometric sensors exhibit many desirable characteristics compared with traditional fiber interferometric sensors based on single-core fibers, such as structural and functional diversity, high integration, space-division multiplexing capacity, etc. Thanks to the unique advantages, e.g., simple fabrication, compact size, and good robustness, MCF interferometric sensors have been developed to measure various physical and chemical parameters such as temperature, strain, curvature, refractive index, vibration, flow, torsion, etc., among which the extraordinary vector-bending sensing has also been extensively studied by making use of the differential responses between different cores of MCFs. In this paper, different types of MCF interferometric sensors and recent developments are comprehensively reviewed. The basic configurations and operating principles are introduced for each interferometric structure, and, eventually, the performances of various MCF interferometric sensors for different applications are compared, including curvature sensing, vibration sensing, temperature sensing, and refractive index sensing.

Coaxial Mach-Zehnder Digital Strain Sensor Made from a Tapered Depressed Cladding Fiber.

An in-line digital optical sensor was proposed. It was built from a tapered depressed-cladding single-mode fiber and modeled as a coaxial Mach-Zehnder interferometer. The principle of operation of the optical digital sensor is based on the computation of the number of optical power transfer turning points (PTTP) from the transmission data of the component. Biconic tapers with high values of PTTP, high spectral resolution, high extinction ratio, and low insertion loss were modeled, fabricated, and characterized. As a proof of concept, an in-line digital strain sensor was fabricated and characterized. It presents a free spectral range of 1.3 nm, and produced 96 PTTP, at λ0 = 1.55 µm, under stretch of ΔL = 707 µm, therefore producing a digital resolution of 7.4 µm/PTTP. The sensor also produced a quasi-symmetric response to stretch and compression.

Non-Invasive Acoustic Monitoring of Gas Turbine Units by Fiber Optic Sensors.

In this article, we study the possibility of gas turbine unit (GTU) monitoring using interferometric fiber optic sensors. We used the Mach-Zehnder interferometer (MZI) scheme, which can be easily implemented and simply installed on the turbine, and also allows us to solve the problem of phase unwrapping conveniently. In this research, the following main steps were carried out: an experimental scheme based on the MZI was assembled, and its sensitive arm was fixed on the GTU under study; data on various operation modes of the GTU was collected; the data were subjected to frequency FFT analysis, based on which the main rotational speeds of the turbine were identified. With FFT analysis, we also demonstrated multiples harmonics, which appear in the case of GTU after operating time, caused by the number of blades. The possibility of GTU monitoring and analysis using a non-invasive compact fiber-optic sensor is demonstrated: spectral analysis is used to detect the rotor speed, as well as the presence or absence of high-order multiple frequencies indicating blade and bearing defects, which are determined by the number of GTU's blades and rolling bearing used as turbines rotor supports.

Highly Modulated In-Fiber Mach-Zehnder Interferometer Based on an Ultracompact Leaky-Guided Liquid Core.

We proposed a novel sensor based on an ultracompact leaky-guided liquid core fiber Mach-Zehnder interferometer (LLCFMZI) for high modulation of an interference spectrum. The sensor structure is based on a micro-sized hollow-core fiber (HCF) splicing a tilt end face single-mode fiber (SMF) to create a miniature oblique gap for the effective access of different liquids. The liquid core with a relatively lower refractive index (RI) than the cladding can achieve a leaky-mode optical waveguide (LMOW) mechanism, and its volume is only approximately 7.85 pL. In addition, the utilized micro-length HCF can reduce the energy loss of core in the LMOW to obtain an acceptable extinction ratio (>30 dB) with high temperature (T) sensitivity in the interference spectra. Experimental results show that the interference spectra can be highly modulated within the wide measurement range of 1250-1650 nm with a steadily linear response for thermal effect. The measured temperature sensitivities (T-sensitivities) of various liquids of DI water, ethanol, and Cargille-liquid (nD = 1.305) are 0.8869, 4.4754, and 4.8229 nm/°C, and the corresponding measured thermal optics coefficient (TOC) are -4.16 × 10-5, -2.11 × 10-4, and -3.6 × 10-4 °C-1, respectively. Measurement results demonstrate that the used liquids with a higher TOC can obtain better T-sensitivity modulation. The highest experimental sensitivity of the liquid-core filled with Cargille-liquid (nD = 1.40) is up to +13.87 nm/°C with a corresponding TOC of -4.07 × 10-4 °C-1. Furthermore, the experimental and theoretical values are in good agreement according to FSR the measuring scheme that investigates the effectiveness of the proposed LLCFMZI.

Impact of Soil-Based Insulation on Ultrahigh-Resolution Fiber-Optic Interferometry.

High resolution optical interferometry often requires thermal and acoustic insultation to reduce and remove environment-induced fluctuations. Broader applications of interferometric optical sensors in the future call for low-cost materials with both low thermal diffusivity and good soundproofing capability. In this paper, we explore the feasibility and effectiveness of natural soil as an insulation material for ultrahigh-resolution fiber-optic interferometry. An insulation chamber surrounded by soil is constructed, and its impact on the noise reduction of a Mach-Zehnder Fabry-Perot hybrid fiber interferometer is evaluated. Our results indicate that soil can effectively reduce ambient noise across a broad frequency range. Moreover, compared to conventional insulation materials such as polyurethane foam, soil shows superior insulation performance at low frequencies and thereby affords better long-term stability. This work demonstrates the practicability of soil as a legitimate option of insulation material for precision optical experiments.

Device architectures for low voltage and ultrafast graphene integrated phase modulators.

The atomic layer thin geometry and semi-metallic band diagram of graphene can be utilized for significantly improving the performance matrix of integrated photonic devices. Its semiconductor-like behavior of Fermi-level tunability allows graphene to serve as an active layer for electro-optic modulation. As a low loss metal layer, graphene can be placed much closer to active layer for low voltage operation. In this work, we investigate hybrid device architectures utilizing semiconductor and metallic properties of the graphene for ultrafast and energy efficient electro-optic phase modulators on semiconductor and dielectric platforms. (1) Directly contacted graphene-silicon heterojunctions. Without oxide layer, the carrier density of graphene can be modulated by the directly contact to silicon layer, while silicon intrinsic region stays mostly depleted. With doped silicon as electrodes, carrier can be quickly injected and depleted from the active region in graphene. The ultrafast carrier transit time and small RC constant promise ultrafast modulation speed (3dB bandwidth of 67 GHz) with an estimated Vπ·L of 1.19 V·mm. (2) Graphene integrated lithium niobite modulator. As a transparent electrode, graphene can be placed close to integrated lithium niobate waveguide for improving coupling coefficient between optical mode profile and electric field with minimal additional loss (4.6 dB/cm). Numerical simulation indicates 2.5× improvement of electro-optic field overlap coefficient, with estimated V π of 0.2 V.

Study of Intra-Chamber Processes in Solid Rocket Motors by Fiber Optic Sensors.

In this study, an experimental study of the burning rate of solid fuel in a model solid propellant rocket motor (SRM) E-5-0 was conducted using a non-invasive control method with fiber-optic sensors (FOSs). Three sensors based on the Mach-Zehnder interferometer (MZI), fixed on the SRM E-5-0, recorded the vibration signal during the entire cycle of solid fuel burning. The results showed that, when using MZI sensors, the non-invasive control of solid fuel burnout is made possible both by recording the time of arrival of the combustion front to the sensor and by analyzing the peaks on the spectrogram of the recorded FOS signal. The main mode of acoustic vibrations of the chamber of the model SRM is longitudinal, and it changes with time, depending on the chamber length. Longitudinal modes of the combustion chamber were detected by MZI only after the combustion front passed its fixing point, and the microphone was unable to register them at all. The results showed that the combustion rate was practically constant after the first second, which was confirmed by the graph of the pressure versus time at the nozzle exit.

In-Line Mach-Zehnder Interferometers Based on a Capillary Hollow-Core Fiber Using Vernier Effect for a Highly Sensitive Temperature Sensor.

In this paper, we propose a highly sensitive temperature sensor based on two cascaded Mach-Zehnder interferometers (MZIs) that work using the Vernier effect. The all-fiber MZIs were assembled by splicing a segment of capillary hollow-core fiber (CHCF) between two sections of multimode fibers (MMFs). This cascaded configuration exhibits a temperature sensitivity of 1.964 nm/°C in a range from 10 to 70 °C, which is ~67.03 times higher than the sensitivity of the single MZI. Moreover, this device exhibits a high-temperature resolution of 0.0153 °C. A numerical analysis was carried out to estimate the devices' temperature sensitivity and calculate the magnification of the sensitivity produced by the Vernier effect. The numerical results have an excellent agreement with the experimental results and provide a better insight into the working principle of the MZI devices. The sensor's performance, small size, and easy fabrication make us believe that it is an attractive candidate for temperature measurement in biological applications.

Small-Sized Interferometer with Fabry-Perot Resonators for Gravitational Wave Detection.

It is highly desirable to have a compact laser interferometer for detecting gravitational waves. Here, a small-sized tabletop laser interferometer with Fabry-Perot resonators consisting of two spatially distributed "mirrors" for detecting gravitational waves is proposed. It is shown that the spectral resolution of 10-23 cm-1 can be achieved at a distance between mirrors of only 1-3 m. The influence of light absorption in crystals on the limiting resolution of such resonators is also studied. A higher sensitivity of the interferometer to shorter-wave laser radiation is shown. A method for detecting gravitational waves is proposed based on the measurement of the correlation function of the radiation intensities of non-zero-order resonant modes from the two arms of the Mach-Zehnder interferometer.

Optical Fiber Based Mach-Zehnder Interferometer for APES Detection.

A 3-aminopropyl-triethoxysilane (APES) fiber-optic sensor based on a Mach-Zehnder interferometer (MZI) was demonstrated. The MZI was constructed with a core-offset fusion single mode fiber (SMF) structure with a length of 3.0 cm. As APES gradually attaches to the MZI, the external environment of the MZI changes, which in turn causes change in the MZI's interference. That is the reason why we can obtain the relationships between the APES amount and resonance dip wavelength by measuring the transmission variations of the resonant dip wavelength of the MZI. The optimized amount of 1% APES for 3.0 cm MZI biosensors was 3 mL, whereas the optimized amount of 2% APES was 1.5 mL.

Ammonia Gas Sensor Based on Graphene Oxide-Coated Mach-Zehnder Interferometer with Hybrid Fiber Structure.

A graphene oxide-coated in-fiber Mach-Zehnder interferometer (MZI) formed with a multimode fiber-thin core fiber-multimode fiber (MMF-TCF-MMF) is proposed and experimentally demonstrated for ammonia gas (NH3) sensing. The MZI structure is composed of two segments of MMF of length 2 mm, with a flame-tapered TCF between them as the sensing arm. The MMFs act as mode couplers to split and recombine light owing to the core diameter mismatch with the other fibers. A tapered TCF is formed by the flame melting taper method, resulting in evanescent wave leakage. A layer of graphene oxide (GO) is applied to the tapered region of the TCF to achieve gas adsorption. The sensor operates on the principle of changing the effective refractive index of the cladding mode of a fiber through changing the conductivity of the GO coating by adsorbed NH3 molecules, which gives rise to a phase shift and shows as the resonant dip shifts in the transmission spectrum. So the concentration of the ammonia gas can be obtained by measuring the dip shift. A wavelength-shift sensitivity of 4.97 pm/ppm with a linear fit coefficient of 98.9% is achieved for ammonia gas concentrations in the range of 0 to 151 ppm. In addition, we performed a repetitive dynamic response test on the sensor by charging/releasing NH3 at concentration of 200 ppm and a relative humidity test in a relative humidity range of 35% to 70%, which demonstrates the reusability and stability of the sensor.

Multi-Particle Interference in an Electronic Mach-Zehnder Interferometer.

The development of dynamic single-electron sources has made it possible to observe and manipulate the quantum properties of individual charge carriers in mesoscopic circuits. Here, we investigate multi-particle effects in an electronic Mach-Zehnder interferometer driven by a series of voltage pulses. To this end, we employ a Floquet scattering formalism to evaluate the interference current and the visibility in the outputs of the interferometer. An injected multi-particle state can be described by its first-order correlation function, which we decompose into a sum of elementary correlation functions that each represent a single particle. Each particle in the pulse contributes independently to the interference current, while the visibility (given by the maximal interference current) exhibits a Fraunhofer-like diffraction pattern caused by the multi-particle interference between different particles in the pulse. For a sequence of multi-particle pulses, the visibility resembles the diffraction pattern from a grid, with the role of the grid and the spacing between the slits being played by the pulses and the time delay between them. Our findings may be observed in future experiments by injecting multi-particle pulses into a Mach-Zehnder interferometer.

Hollow-Core Photonic Crystal Fiber Mach-Zehnder Interferometer for Gas Sensing.

A novel and compact interferometric refractive index (RI) point sensor is developed using hollow-core photonic crystal fiber (HC-PCF) and experimentally demonstrated for high sensitivity detection and measurement of pure gases. To construct the device, the sensing element fiber (HC-PCF) was placed between two single-mode fibers with airgaps at each side. Great measurement repeatability was shown in the cyclic test for the detection of various gases. The RI sensitivity of 4629 nm/RIU was demonstrated in the RI range of 1.0000347-1.000436 for the sensor with an HC-PCF length of 3.3 mm. The sensitivity of the proposed Mach-Zehnder interferometer (MZI) sensor increases when the length of the sensing element decreases. It is shown that response and recovery times of the proposed sensor inversely change with the length of HC-PCF. Besides, spatial frequency analysis for a wide range of air-gaps revealed information on the number and power distribution of modes. It is shown that the power is mainly carried by two dominant modes in the proposed structure. The proposed sensors have the potential to improve current technology's ability to detect and quantify pure gases.

Design Rule of Mach-Zehnder Interferometer Sensors for Ultra-High Sensitivity.

A design rule for a Mach-Zehnder interferometer (MZI) sensor is presented, allowing tunable sensitivity by appropriately choosing the MZI arm lengths according to the formula given in this paper. The present MZI sensor designed by this method can achieve an ultra-high sensitivity, which is much higher than any other traditional MZI sensors. An example is given with silicon-on-insulator (SOI) nanowires and the device sensitivity is as high as 106 nm/refractive-index -unit (or even higher), by choosing the MZI arms appropriately. This makes it possible for one to realize a low-cost optical sensing system with a detection limit as high as 10-6 refractive-index-unit, even when a cheap optical spectrum analyzer with low-resolution (e.g., 1 nm) is used for the wavelength-shift measurement.