AI-accelerated Nazca survey nearly doubles the number of known figurative geoglyphs and sheds light on their purpose.

It took nearly a century to discover a total of 430 figurative Nazca geoglyphs, which offer significant insights into the ancient cultures at the Nazca Pampa. Here, we report the deployment of an AI system to the entire Nazca region, a UNESCO World Heritage site, leading to the discovery of 303 new figurative geoglyphs within only 6 mo of field survey, nearly doubling the number of known figurative geoglyphs. Even with limited training examples, the developed AI approach is demonstrated to be effective in detecting the smaller relief-type geoglyphs, which unlike the giant line-type geoglyphs are very difficult to discern. The improved account of figurative geoglyphs enables us to analyze their motifs and distribution across the Nazca Pampa. We find that relief-type geoglyphs depict mainly human motifs or motifs of things modified by humans, such as domesticated animals and decapitated heads (81.6%). They are typically located within viewing distance (on average 43 m) of ancient trails that crisscross the Nazca Pampa and were most likely built and viewed at the individual or small-group level. On the other hand, the giant line-type figurative geoglyphs mainly depict wild animals (64%). They are found an average of 34 m from the elaborate linear/trapezoidal network of geoglyphs, which suggests that they were probably built and used on a community level for ritual activities.

Asymmetric faces: Symbolic, spiritual, and representative.

In humans, physically attractive faces are measurably, though subtly, asymmetric. As asymmetry increases, it has a negative impact. Medically, asymmetry can be congenital or acquired. Symbolically, it has varied connotations from playfulness and complexity to despair and corruption. In Chinese opera, stylized make-up exaggerates the features, and aspects of the "mask" indicate qualities of the character. The asymmetric faces belong to characters who are corrupt, devious, or evil. In the Dan culture of western Africa, performance masks channel spirits in the community. A spirit with asymmetric facial mask exemplifies ugliness and moral failing. The Nasca culture of South America made generic figures of farmers, deities, and so on, but not of individuals. However, there is evidence of mutual influence between the Nasca and the Wari, with whom they traded. A clay figure apparently representing an individual, or at least a very specific recognized persona, is a ball player with facial asymmetry presumably due to injury. Here the message is one of fierceness and strength. The relative rarity of asymmetric facial depictions compared to symmetric ones is cross-cultural. This implies that asymmetry is special somehow, in all connotations of that term.

Reconstruction of full high-resolution HSQC using signal split in aliased spectra.

Resolution enhancement is a long-sought goal in NMR spectroscopy. In conventional multidimensional NMR experiments, such as the (1) H-(13) C HSQC, the resolution in the indirect dimensions is typically 100 times lower as in 1D spectra because it is limited by the experimental time. Reducing the spectral window can significantly increase the resolution but at the cost of ambiguities in frequencies as a result of spectral aliasing. Fortunately, this information is not completely lost and can be retrieved using methods in which chemical shifts are encoded in the aliased spectra and decoded after processing to reconstruct high-resolution (1) H-(13) C HSQC spectrum with full spectral width and a resolution similar to that of 1D spectra. We applied a new reconstruction method, RHUMBA (reconstruction of high-resolution using multiplet built on aliased spectra), to spectra obtained from the differential evolution for non-ambiguous aliasing-HSQC and the new AMNA (additional modulation for non-ambiguous aliasing)-HSQC experiments. The reconstructed spectra significantly facilitate both manual and automated spectral analyses and structure elucidation based on heteronuclear 2D experiments. The resolution is enhanced by two orders of magnitudes without the usual complications due to spectral aliasing.

Advances in regional paleopathology of the Southern Coast of the Central Andes.

Because of a rich cultural history and excellent preservation of archaeological materials the south coast of the Central Andes is a region where many anthropological questions can be explored, using the latest methods and techniques. Over the last 20 years, multidisciplinary paleopathological studies have revealed interesting and unanticipated perspectives regarding the lives and cultures of the peoples who inhabited this region in pre-Hispanic times. This paper presents a panorama of these recent investigations, beginning with a review of the data sources - the collections of human remains - available for study, their numbers, preservation, accessibility, strengths and weaknesses. Then follows a revision of recent investigations, presenting new knowledge about temporal trends in human health in the region, including mortality curves, stature achieved in adulthood, porotic hyperososis, cribra orbitalia, linear enamel hypoplasias, dental caries, biochemical analysis, trauma, and violence. This review shows how the knowledge of the history of this region has increased but also the many new questions that have emerged. Hopefully this paper will encourage more investigation, as the collections of human remains from this region are abundant, well documented and well preserved.

A 'cold case' of care: Looking at old data from a new perspective in mummy research.

In 1973, analysis of the mummified remains of a young boy dated to 700AD and from the Late Nasca period (Peru) identified (i) chronic Pott's disease, leading to loss of lower body mobility, and (ii) acute miliary tuberculosis, affecting most organs and the immediate cause of death (Allison et al., 1973). This report was the first to establish, beyond dispute, the presence of tuberculosis in the Americas before the arrival of Europeans. Here, we revisit the 'Nasca Boy' from a bioarchaeology of care perspective. Contextualising the original study's results within what is known of contemporary lifeways, we apply the bioarchaeology of care methodology in considering the Nasca Boy's experience of living with tuberculosis; the type of care he required and how this may have evolved over a period of deteriorating health; and what such caregiving may suggest both about social organisation within his community and some of the more everyday aspects of Nasca existence. Up to now, the bioarchaeology of care approach has been employed almost exclusively with skeletal evidence; in this analysis of the Nasca Boy's remains, and in the accompanying wider-ranging discussion, we illustrate the potential of preserved soft tissue evidence to contribute to research into disability and care in the past. Although this report functions as a stand-alone case study, to obtain maximum benefit it should be read in conjunction with the Introduction to the special International Journal of Paleopathology issue on 'mummy studies and the bioarchaeology of care' (Nystrom and Tilley, 2018).

Pott's disease: a case of Mycobacterium xenopi infection of the spine.

Pott's disease is an infection of the spine with Mycobacterium tuberculosis that causes destruction of the spine elements resulting in progressive kyphosis. We are describing a rare case of Pott's disease where Mycobacterium xenopi was the inculpated organism.