Brief Report: Determinants of Potential Sexual Activity Reduction in the Face of the Mpox Epidemic.

BACKGROUND: The current mpox epidemic is most prevalent among men-who-have-sex-with-men (MSM). Vaccination programs are being rolled-out to curb the epidemic. Behavioural measures have been called for as well, for example, by the WHO and national public health authorities to reduce the number of sexual partners and sexual activity. We investigated intentions and determinants among Dutch MSM to follow such behavioural measures. METHODS: Early in July 2022, in the context of a dynamic ongoing epidemic, 394 MSM answered an online questionnaire investigating concepts such as perceived mpox risk, vaccination and behavioural change intentions and collecting socio-demographic and sexual behaviour information. RESULTS: The overall intentions to reduce number of partners and sexual activity were high, but only a minority had developed definite intentions. Determinant analysis revealed that dating/open relationship status was a positive predictor; vaccination intentions did not predict sexual behaviour change; those not on PrEP were more likely to change their sexual behaviour. Mpox infection concern was the main predictor for behaviour change intentions. CONCLUSIONS: Our results show that behavioural measures to avoid an mpox infection are present in majority of participants in our survey, but high intentions are held by a minority. Taking the historic complexity of behavioural change pleas among MSM into account sensitive, additional public health measures are necessary to reach and to inform MSM about potential benefits of sexual behaviour change.

How online data informs forensic mental health evaluations of sexual behavior: An overview.

The Internet plays a pervasive role in modern life including the expression of human sexuality and sexual offending. A range of online sexual activities may be of interest in forensic mental health evaluations (FMHE), including those which are clearly illegal or those which are legal but functionally problematic. Online sexual offenses will clearly prompt forensic evaluators to consider the role of the Internet in these offending behaviors. The Internet may also be relevant in forensic evaluations of contact sexual offending including informing on history of mixed or cross-over offending, and Internet-facilitated contact offenses. A review of Internet-data may span several online domains, many of which provide the user with substantial anonymity and would likely not be available to the evaluator unless provided through the process of discovery. Early guidelines for the review of Internet-data in FMHEs have been proposed and support the Internet as a useful source of collateral data in the conduct of forensic evaluations of sexual behavior.

Prevalence, Pattern and Factors Associated with Online Sexual Activity among Final Year Students in Osun State University, Nigeria.

BACKGROUND: The internet has opened up new avenues for sexual exploration, including online sexual activity (OSA), which is becoming increasingly common among young adults globally. This study aimed to investigate the prevalence, patterns, and associated factors of OSA among final-year students in Osun State University, Nigeria. METHODS: A descriptive cross-sectional study was carried out among 436 undergraduates. Respondents were selected via a multistage sampling technique; a semi-structured self-administered questionnaire was used for data collection and analyses. Online sexual activity was measured with the Internet Sex Screening Test (ISST) and pertinent analyses were done at univariate, bivariate and multivariate levels using SPSS V20.0. RESULTS: The prevalence of OSA was 58.7%, It is more common among males (53.1%) than females (46.9%), 73.4% of the undergraduates were mildly involved, and none was severely involved. Factors associated with OSA include biological sex, dating, smoking and/or usage of substances exposure to pornography from childhood, religiosity and family functioning. Further analysis showed that males are three times more likely to be involved in OSA compared to females (AOR= 3.104, p<0.001, CI-1-936-4.977). Those dating are two and a half times more likely to be involved in OSA (AOR= 2.491, p<0.001, CI- 1.589-3.905). Also, those who smoked and/or use other substances or are exposed to pornography from childhood as well as those who have a low level of religiosity are more likely to be involved in OSA. CONCLUSION: OSA was prevalent among final-year students, particularly among males and those dating. The association between substance use and OSA among young people is not likely to be an unstable one and both are increasingly available to them, with the almost inevitable possibility that increased usage of substances may tilt many into severe or addictive online sexual activities. Thus, targeted enlightenment/ education on OSA and on substance use is recommended for undergraduates.

CONTEXTE: L'internet a ouvert de nouvelles voies pour l'exploration sexuelle, y compris l'activité sexuelle en ligne (ASO), qui devient de plus en plus courante chez les jeunes adultes dans le monde. Cette étude visait à examiner la prévalence, les modèles et les facteurs associés de l'ASE parmi les étudiants de dernière année de l'Université de l'État d'Osun, au Nigéria. MÉTHODES: Une étude transversale descriptive a été menée auprès de 436 étudiants de premier cycle. Les répondants ont été sélectionnés au moyen d'une technique d'échantillonnage à plusieurs degrés ; un questionnaire semi-structuré auto-administré a été utilisé pour la collecte et l'analyse des données. L'activité sexuelle en ligne a été mesurée à l'aide de l'Internet Sex Screening Test (ISST) et des analyses pertinentes ont été effectuées aux niveaux univarié, bivarié et multivarié à l'aide de SPSS V20.0. RÉSULTATS: La prévalence du SAOS était de 58,7 %, plus fréquente chez les hommes (53,1 %) que chez les femmes (46,9 %), 73,4 % des étudiants de premier cycle étaient légèrement atteints et aucun n'était gravement atteint. Les facteurs associés au SAOS sont le sexe biologique, les fréquentations, le tabagisme et/ou l'utilisation de substances, l'exposition à la pornographie pendant l'enfance, la religiosité et le fonctionnement de la famille. Une analyse plus poussée a montré que les hommes sont trois fois plus susceptibles d'être impliqués dans l'AOS que les femmes (AOR= 3,104, p<0,001, CI-1-936-4,977). Les personnes qui sortent avec quelqu'un sont deux fois et demie plus susceptibles de souffrir d'un SAOS (AOR= 2.491, p<0.001, CI- 1.589-3.905). En outre, les personnes qui fument et/ou consomment d'autres substances ou qui sont exposées à la pornographie depuis l'enfance, ainsi que celles qui ont un faible niveau de religiosité, sont plus susceptibles d'être impliquées dans l'AOS. CONCLUSION: Le SAOS est répandu parmi les étudiants de dernière année, en particulier chez les hommes et ceux qui sortent avec quelqu'un. L'association entre la consommation de substances et l'AOS chez les jeunes ne devrait pas être instable et les deux sont de plus en plus accessibles, avec la possibilité presque inévitable qu'une consommation accrue de substances puisse faire basculer de nombreuses personnes dans des activités sexuelles en ligne sévères ou addictives. Il est donc recommandé d'informer et d'éduquer les étudiants de premier cycle sur le SAOS et la consommation de substances psychoactives. Mots-clés: Activités sexuelles en ligne, Schéma, Prévalence, Consommation de substances, Étudiants de premier cycle.

Sex Differences in the Pathways from Exposure to Parental Fighting to Risky Sexual Activities Among Adolescents in Urban Neighborhoods.

OBJECTIVES: Adolescents' exposure to violence between parents acts as a precursor to risky behaviors; however, empirical studies that examined the potential pathways from exposure to violence between parents to risky behaviors are rare. Consequently, the prevention and intervention strategies for risky sexual activities are limited without the identification of malleable mediators. METHODS: Mediators on the association between adolescent exposure to parental fighting and risky sexual activities are examined, which include internalizing behaviors, running away from home, and affiliation with risky peers. Relationships between these variables are examined for males and females separately. The sample consists of 673 adolescents in a neighborhood located in Chicago's Southside who completed a survey. RESULTS: Exposure to parental fighting was not directly associated with risky sexual activities for either males or females. However, among females, exposure to parental fighting was significantly and positively related to internalizing behaviors and running away from home, and internalizing behaviors were also positively associated with running away from home. For males, however, only the association between internalizing behaviors and running away from home was found to be significant. Further, the relationship between exposure to parental fighting and risky sexual activities was mediated by running away from home. CONCLUSIONS: Targeted strategies for prevention are critical for improving sexual health outcomes among adolescents in low-resourced urban neighborhoods.

Diversity of sexual activity and correlates among women with gynecological cancer.

OBJECTIVE: Sexual dysfunction has been reported in women following treatment for gynecological cancer. However, the actual sexual activities adopted by these women are not well understood. The aims of this study were to (1) explore a relatively new concept, diversity of sexual activities (DSA), and (2) identify factors associated with DSA in women with gynecological cancer. METHODS: This cross-sectional study included 136 Taiwanese long-term partnered women with gynecologic cancer treated in a large medical center. DSA was measured with the Diversity of Sexual Activities Scale, which assesses the number of sexual activities adopted in the past 6 months. Covariates included sexual knowledge and sexual attitudes, perceived changes in relationships of intimacy since treatment, and demographic and clinical factors. RESULTS: The mean age of participants was 51.2 years (SD = 8.66); cancer diagnoses were cervical (50.7%), endometrial (31.6%), and ovarian (17.6%). The mean number of sexual activities was 2.88 (SD = 2.63); 29.4% of participants had no physical contact with their partners after treatment. The participants reported a significantly decreased overall satisfaction toward adopted sexual activities after cancer treatment. Lower DSA was associated with older age and receiving a combination of chemotherapy and radiotherapy. CONCLUSIONS: Cancer treatment has a significant impact on sexual activity in women with gynecological cancer. Around 30% of participants reported not having any physical contact with their partners since receiving cancer treatment. Sexual rehabilitation counseling that emphasizes alternative forms of sexual expression is suggested.

Qualitative and quantitative aspects of sex life in the context of endometriosis: a multicentre case control study.

RESEARCH QUESTION: What are the specific characteristics of sexual activity in women with endometriosis compared with women without endometriosis? DESIGN: Multicentre case control study. Participants were recruited from university hospitals, district hospitals and doctor's offices in Germany, Switzerland and Austria. A total of 565 women with endometriosis were pair-matched to 565 control women by age and ethnic background. Diagnosis of endometriosis was confirmed by histology, and disease stage was classified according to American Society for Reproductive Medicine criteria. Data on sexuality were collected using selected questions from the Brief Index of Sexual Function and the Sexual History Form. RESULTS: Altogether, 69.1% of women with endometriosis and 77.8% of control women engaged in sexual activity during the month before the study period (P < 0.001). Overall, 42.3% of endometriosis-affected women and 30.5% of the control women desired a higher frequency of sexual activity (P < 0.001). Petting, foreplay and vaginal sexual intercourse were reported to be practised less often by women with endometriosis. Frequencies for masturbation, reciprocal masturbation, oral and anal sex were similar in both groups. Dyspareunia was negatively associated with sexual activity (OR 2.42, 95% CI 1.26 to 4.63), whereas chronic pain showed no association with sexual activity (OR 1.35, 95% CI 0.93, 1.96). CONCLUSIONS: Women with endometriosis have lower frequencies of petting, foreplay and vaginal sexual intercourse than control women; this difference has to be attributed, at least in part, to dyspareunia. Potentially pain-free sexual options are used to a limited degree. As endometriosis-affected women desire higher levels of sexual activity, sexual counselling should be included in medical support.

Sexual Satisfaction and Frequency of Orgasm in Women With Chronic Pelvic Pain due to Endometriosis.

BACKGROUND: Dyspareunia, one of the main symptoms of the chronic gynecological pelvic pain disorder endometriosis, may interfere with the likelihood of reaching an orgasm, yet for women with dyspareunia, no data on orgasm rates in different sexual activities are available. AIM: The aim of this study was to evaluate the ability to reach an orgasm and its association with sexual satisfaction during different sexual activities in women with a chronic pelvic pain disorder and in healthy control women. METHODS: A set of questionnaires including the brief index of sexual functioning and global sexual functioning was used to evaluate sexuality in women affected with endometriosis (n = 434) and a nonaffected control group (n = 434) recruited in German-speaking countries. OUTCOMES: The primary outcome measure of this study was the orgasm rate during different types of sexual activities. RESULTS: Only the ability to have an orgasm during sexual intercourse (P = .002) but not during masturbation (P = .509) or partnered noncoital sexual activities (P = .229) is affected by endometriosis. Dyspareunia was associated with a reduced ability to experience an orgasm during intercourse for endometriosis patients (P = .020) and control women (P = .006). The ability to orgasm during noncoital sexual activities (P = .006) and sexual intercourse (P = .038) was associated with a higher sexual satisfaction in women with endometriosis. For controls, only the ability to achieve an orgasm with sexual intercourse was associated with sexual satisfaction (P = .038). CLINICAL IMPLICATIONS: Sexual counselling as part of medical support could help couples living with chronic pelvic pain of the female partner integrate noncoital sexual activities in their sex lives, leading to fewer sex-related problems and higher sexual desire and satisfaction. STRENGTHS AND LIMITATIONS: This study is the first to examine different ways of achieving an orgasm and sexual satisfaction in a large group of women with endometriosis and a matched control group. The breadth of the questionnaire allowed a differentiated analysis of factors influencing the likelihood of achieving an orgasm and overall sexual satisfaction. The one limitation is that the length and the intimate nature of the questionnaire possibly resulted in reluctance to answer this part of the questionnaire. CONCLUSION: Partnered noncoital sexual activities may represent an alternative to reach orgasm for women with endometriosis-related chronic pelvic pain or anorgasmia during sexual intercourse. Hämmerli S, Kohl-Schwartz A, Imesch P, et al. Sexual Satisfaction and Frequency of Orgasm in Women With Chronic Pelvic Pain due to Endometriosis. J Sex Med 2020;17:2417-2426.

Challenges in the Practice of Sexual Medicine in the Time of COVID-19 in China.

BACKGROUND: In March 2020, the World Health Organization declared coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a pandemic. Currently, data on changes in sexual behavior during the COVID-19 outbreak are limited. AIM: The present study aimed to obtain a preliminary understanding of the changes in people's sexual behavior, as a result of the pandemic, and explore the context in which they manifest. METHODS: A convenience sample of 270 men and 189 women who completed an online survey consisting of 12 items plus an additional question were included in the study. OUTCOMES: The study outcomes were obtained using a study-specific questionnaire to assess the changes in people's sexual behavior. RESULTS: While there was a wide range of individual responses, our results showed that 44% of participants reported a decrease in the number of sexual partners and about 37% of participants reported a decrease in sexual frequency. Multiple regression analysis showed that age, partner relationship, and sexual desire were closely related to sexual frequency. In addition, we found that most individuals with risky sexual experiences had a rapid reduction in risky sexual behavior. CLINICAL IMPLICATIONS: The current findings contribute to identifying another potential health implication associated with the COVID-19 pandemic and report preliminary evidence of the need to provide potential interventions for the population. STRENGTH & LIMITATIONS: This study is the first to perform a preliminary exploration of sexual behavior during the COVID-19 outbreak. The generalizability of the results is limited, given that only a small convenience sample was used. CONCLUSION: During the height of the COVID-19 outbreak, overall sexual activity, frequency, and risky behaviors declined significantly among young men and women in China. Li W, Li G, Xin C, et al. Challenges in the Practice of Sexual Medicine in the Time of COVID-19 in China. J Sex Med 2020;17:1225-1228.

[Is sexual activity during adolescence good for future romantic relationships?] / Sind sexuelle Aktivitäten in der Adoleszenz für zukünftige Partnerbeziehungen gut?

Is sexual activity during adolescence good for future romantic relationships? Objectives: The study examines the effects of different forms of sexual activity at the age of 16 on sexuality and the quality of romantic relationships at the age of 23. Methods: In a multimodal longitudinal study (diaries, questionnaires), 144 16-year-old adolescents (59.7 % female) reported on their sexual activities and their relationship status. At the age of 23, they reported on their romantic and sexual experiences in the past two years and the quality of their current romantic relationship. Regressions analyzed the predictive power of adolescent predictors for future sexuality and relationship quality. Results: For men and women, frequent non-committed sexual activities at the age of 16 consistently predicted a higher probability of participating in different patterns of non-committed sexual encounters and short relationship duration at the age of 23 years. Adolescents who were more satisfied in their romantic relationships had more stable, longer-lasting partner relationships at young adulthood. Discussion: The special role that non-committed sexual activities compared to sexual activities within a romantic relationship play in future sexual and romantic activities became clear. Parental influences were negligible.

Relationship of Specific Sexual Activities to Orgasmic Latency, Pleasure, and Difficulty During Partnered Sex.

INTRODUCTION: Specific sexual activities during partnered sex are likely to affect orgasmic parameters, such as latency, pleasure, and difficulty, but such relationships have not been examined in detail. AIM: To ascertain whether specific kinds of sexual activities account for variation in orgasmic latency, pleasure, and difficulty during partnered sex. METHOD: Participants were 2,068 women drawn from community-based samples in the United States and Hungary who completed an investigator-derived questionnaire regarding their sexual history and response, including items related to frequency of masturbation and partnered sex, sexual desire, sexual arousal, orgasmic response, orgasmic latency, distress, partner distress, and sexual satisfaction. MAIN OUTCOME MEASURES: Self-reported orgasmic latency, pleasure, and difficulty during partnered sex were assessed. RESULTS: Orgasmic pleasure and orgasmic difficulty were related to the types of sexual activities incorporated into partnered sex. Nevertheless, relationship satisfaction played as large a role in both orgasmic parameters. Orgasmic latency, on the other hand, was less affected by the type of sexual activity during partnered sex, but it was also affected by relationship satisfaction and orgasmic difficulty. CLINICAL IMPLICATION: Addressing relationship satisfaction and expanding the behavioral repertoire of activities during partnered sex may increase sexual satisfaction and mitigate orgasmic difficulty. STRENGTH & LIMITATIONS: The study, well powered and drawing from a multinational population, is 1 of the few to analyze specific types of sexual activity and stimulation during partnered sex. Major limitations were the younger age and self-selection of the sample. CONCLUSION: Type and conventionality of sexual activities during partnered sex affect orgasmic pleasure and difficulty. Rowland DL, Kolba TN. Relationship of Specific Sexual Activities to Orgasmic Latency, Pleasure, and Difficulty during Partnered Sex. J Sex Med 2019;16:559-568.

Deviant Cyber-Sexual Activities in Young Adults: Exploring Prevalence and Predictions Using In-Person Sexual Activities and Social Learning Theory.

Technology has shifted some human interactions to the virtual world. For many young adults, sexual encounters now occur through virtual means, as social media, picture exchanges, sexually explicit Web sites, and video chatting have become popular alternative outlets for these activities to occur. This study used the self-report responses of 812 undergraduate students (282 men and 530 women), collected from an online survey. In addition to using 10 personal demographic control variables, this study used five sexual activity/relationship characteristics (number of sexual partners, relationship status, age to first use pornography, frequency of sexual activity/intercourse, and frequency of masturbation), and the four constructs of Akers' social learning theory (identified as differential association, differential reinforcement, imitation/modeling, and definitions favorable) to predict a seven-item count of deviant cyber-sexual activities, and two measures of "sexting" behaviors. Gender, self-esteem, sexual orientation, race, and religion were strongly significant predictors in the models, but Akers' four elements of social learning performed the strongest in predicting the two measures of sexting and the overall deviant cyber-sexual activities scale. This finding indicates that peer associations and peer reinforcements have a strong influence on individuals' willingness to engage in deviant cyber-sexual activities. This study explored different avenues for young adults' engagement in sexual deviancy and the results suggest that sexual behaviors performed in-person may not be the strongest predictors of online sexual behavior.

Sexual behavior and symptoms among reproductive age Chinese women in Hong Kong.

INTRODUCTION: As sexual medicine evolves, much advancement has been achieved in understanding male sexuality and treating male sexual dysfunction. Less is known about female sexual pattern, the prevalence of sexual problems, and their correlation with confounding factors. AIM: To enhance our understanding of female sexuality and the risk factors that contributed to sexual problems in reproductive age women. METHOD: A cross-sectional survey was conducted in family planning and prepregnancy checkup clinics from December 2007 to December 2009, with 2,146 sexually active Chinese women aged 21 to 40 years completed the entire questionnaire. MAIN OUTCOME MEASURES: Prevalence of sexual symptoms, coital frequency, and other sexual behavior-related activities were measured. RESULTS: Overall, 59.0% of respondents had at least one sexual problem. In this sample, 31.8% of respondents reported no desire; 31.7% had arousal problems; 40% had anorgasmia, and 33.8% experienced coital pain for at least 3 months within the past 1 year. Chi-square test showed significant correlation among the four types of sexual problems(P < 0.001). Univariate regression model showed that all sexual symptoms were significantly correlated with unidirectional coitus initiation, low coital frequency, and low foreplay enjoyment. Loglinear model revealed that desire, arousal, and orgasmic problems were correlated with low foreplay enjoyment. Arousal problem was correlated with high acceptance toward pornography and history of medical disease. Coital pain was correlated with secondary education and planning to have more children. Both unidirectional coitus initiation and low coital frequency were major contributors to all four sexual symptoms. CONCLUSIONS: Sexual problem is a prevalent health issue among reproductive age women. A number of risk factors are identified, which provide useful direction to the design of counseling and education materials that might help to enhance sexual performance in women.

Determinants of Contraceptive Options among Postpartum Women Attending Selected Health Care Facilities in Nigeria: A Cross-Sectional Study.

Introduction: Differences in availability and choices of contraceptive methods among postpartum women have been found to influence their quality of life as the fertility rate is very high, and the contraceptive usage rate persistently remains low in Nigeria. Objectives: This study assessed the determinants of contraceptive options among postpartum women in Nigeria. Methods: Two Local Governments were randomly selected from the four Local Governments. Within these two local governments, five health facilities were selected. A multistage sampling technique was used to select the 240 respondents, while a structured questionnaire was used to collect data. Results: Findings from the study indicated that 81.7% of the respondents have planned to have their current baby, and about 65.4% of the women have resumed sexual activities since delivery. Of those who have resumed sexual activities, the majority, 91.1% did so 6 weeks after delivery. Some form of contraceptive usage was prominent among 59.2% of the respondents, as the most common contraceptive method used was withdrawal (24.8%). Contraceptive prevalence was slightly lower for urban respondents than rural respondents, although the relationship was not significant. Also, there was a statistically significant relationship between the current use of contraceptives and resumption of sexual activities since delivery (p = .001), resumption of menstruation (p = .001), and information received about postpartum family planning (p = 0.013). Conclusion: Findings from this study emphasize the urgent need for enhanced accessibility and availability of contraceptive methods, with a parallel emphasis on targeted interventions and effective communication strategies to promote contraceptive uptake and family planning. Addressing these determinants is vital in improving postpartum women's overall quality of life in the study area.

Impact of Treatment With Sacubitril/Valsartan on Erectile Dysfunction in Patients With Heart Failure With Reduced Ejection Fraction.

Sacubitril/valsartan (S/V), an angiotensin receptor-neprilysin inhibitor, has been shown to reduce the risk of cardiovascular death or heart failure hospitalization and relieve symptoms in patients with chronic heart failure with reduced ejection fraction. The objective of this study was to assess the effects of S/V on erectile dysfunction in patients with heart failure with reduced ejection fraction (HFrEF). A prospective, open-label study was conducted with 59 male patients diagnosed with HFrEF and concomitant erectile dysfunction. Patients were treated with S/V for a duration of 1 month. The International Index of Erectile Function (IIEF) questionnaire was used to assess the severity of erectile dysfunction and sexual activities at baseline and follow-up visits. Other clinical parameters, including heart rate, were also monitored. After S/V treatment, a significant improvement was observed in sexual activities at the 1-month follow-up visit. The IIEF score showed a statistically significant increase, indicating a decrease in the severity of erectile dysfunction. However, it should be noted that the numerical increase in the IIEF score did not reach clinical significance. This study suggests that S/V treatment in patients with HFrEF may lead to improvements in sexual activities and a reduction in the severity of erectile dysfunction as measured by the IIEF score.

Effect of COVID-19 on sexual function and activities among reproductive-age women in Ibadan, South-West Nigeria.

Background: Since the outbreak of COVID-19 disease, the environment, families, individuals, and their ways of living have been affected. Social distancing was one of the strategies for the prevention of SARS-CoV-2 infection. It led to limited social interactions for fear of contracting the infection, which ultimately affected relationships, among which is sexual health. Aim: To determine the risk of female sexual dysfunction and the effect of the COVID-19 pandemic on sexual function and activities among women of reproductive age in Ibadan, South-West Nigeria. Methods: This cross-sectional study of 218 reproductive-age women evaluated the sexual function before, during, and after the COVID-19 disease pandemic and lockdown. Pretested semistructured self-administered questionnaires with the Female Sexual Function Index (FSFI) were used for data collection. Information collected included sociodemographic and gynecologic characteristics and COVID-19 experiences, as well as sexual history and function before, during, and after the COVID-19 pandemic lockdown. The level of significance was set at P < .05. Outcomes: Respondents were aged 20 to 50 years (95%) with a mean ± SD age of 34.82 ± 8.52 years; the majority were married (75.58%); one-fifth (21.9%) tested positive for COVID-19 infection; and participants who tested positive for COVID-19 infections were mostly health care workers. Results: An absence of sexual activity was reported in 9.18% of participants during lockdown, 7.73% before lockdown, and 4.18% after lockdown. The risk of female sexual dysfunction was prevalent among participants, especially those who tested positive for COVID-19 infection. The prevalence was worse during the pandemic lockdown (53.57%) than before (48.39%) or after (51.61%), and a similar pattern was seen among those who tested negative. There was no statistically significant difference in risk of developing sexual dysfunction during the COVID-19 pandemic between those who tested positive and negative to COVID-19. The arousal and desire domains contributed the highest proportion of low FSFI scores. Clinical Implications: Nationwide lockdowns, which may be a method of control for pandemics, may result in psychosocial complications such as female sexual dysfunction. Strength and Limitations: Most respondents had tertiary education and were able to respond to self-administered questionnaires, yet the risk of recall bias remains a concern whereas the pandemic met the world unprepared and baseline FSFI prior the pandemic was not available for participants. There are no local validation studies for the FSFI in Nigeria, which could have aided interpretation of results. Conclusion: A low FSFI score is prevalent in Ibadan, South-West Nigeria, with a higher incidence reported during the COVID-19 pandemic lockdown.

Vitagnus an estrogen-riched herbal remedy used in sexual dysfunction: A randomized clinical trial.

BACKGROUND: Sexual dysfunction is a common problem in the postmenopausal period. Vitagnus is a phytoesterogen containing herb, which can bind to estrogen receptors and modulate their function. In this study, we evaluated the efficacy of oral vitagnus solution on sexual dysfunction improvement among postmenopausal women in North Khorasan Province, Iran. MATERIALS AND METHODS: The present study was a double-blind clinical trial on 60 retired female teachers who visited the retirement center of North Khorasan Province from December 2019 until January 2021. Sampling was done in a convenience sampling. Allocation of intervention and placebo groups was done randomly by marking as A and B codes, respectively. Eligible married women aged 50-70 years had received 40 drops of vitagnus or placebo daily for 8 weeks. Female Sexual Function Index was filled on the first day, fourth, sixth, and eighth week after the intervention. Data were analyzed using SPSS V.23 and independent t-test, Mann-Whitney U, Chi-square, Fisher's exact test, and repeated measure ANOVA were used for analyzing descriptive and inferential data. P < 0.05 was considered as a statistically significant threshold. RESULTS: Data from Bonferroni post hoc test indicated that the mean total sexual function did not differ between the two groups before and at the end of the fourth week of intervention, but scores of total sexual function showed a significant difference at the end of the sixth (P = 0/003) and eighth week (P = 0/001) of intervention. CONCLUSION: Vitagnus drops, as a simple, cheap, and available herbal supplement, could affect the sexual function of women aged 50-70 and improve it.

The effects of letrozole-induced maternal hyperandrogenism on sexual behaviors, testicular histology, and serum biochemical traits in male offspring rats: An experimental study.

Background: Intrauterine endocrine abnormalities have profound effects on the development of physiological disorders. Objective: This study aimed to assess the effects of in utero exposure to letrozole (an aromatase inhibitor) and its late consequences on the reproductive and metabolic performance of an adult male offspring. Materials and Methods: 15 pregnant Sprague-Dawley rats (8 wk, 155 gr) were randomly assigned into 5 experimental groups (n = 3/each) and orally received either letrozole at doses of 0.25, 0.75, 1.00, and 1.25 mg/kg body weight (BW) or vehicle (control) on the gestation days of 16, 17, and 18. Pregnancy outcome, sexual behaviors on postnatal day 60, serum biochemical features, and the histopathology of testes were assessed in male offspring. Results: Compared to control group, delayed labor (21.83 vs. 24.25, p < 0.0001) and reduced litter size (n = 12.25 vs. n = 2, p < 0.0001) were recorded in 1.25 mg/kg BW group. A reduction in high-density lipoprotein level and the elevation of testes weight, BW gain, anogenital distance, as well as the serum concentrations of testosterone, triglycerides, cholesterol, and glucose were observed in 1.25 mg/kg BW (p < 0.0001) and 1.00 mg/kg BW (p < 0.0001) groups in comparison to control. A larger number of anogenital female sniffing, pursuit, and mounting behaviors were also observed in 1.25 mg/kg BW group in comparison to control (p < 0.0001). Severe testicular defects including necrosis and disruption of the epithelium of seminiferous tubules, sloughing of epithelial cells, and spermatogenesis arrest were observed in letrozole-treated groups, in a dose-dependent manner. Conclusion: Maternal exposure to letrozole can adversely affect the reproductive and metabolic performance of male offspring rats, suggesting an incomplete sex differentiation.

Sexting Behaviors Before and During COVID-19 in Italian and Colombian Young Adults.

Introduction: Recent research highlight increasing at-risk online sexual activities and behaviors during the COVID-19 pandemic among young adults. Specifically, sexting refers to exchanging sexually suggestive messages, photos, and videos through technological devices, and it can be placed on a continuum from safer to riskier behavior. This study aims to improve our knowledge about sexting behaviors in Italian and Colombian young adults before and during the COVID-19 pandemic. Methods: A survey online was filled in by all recruited participants through a snowball sampling procedure (from December 2019 to June 2021) both in Italy and Colombia, resulting in a total of 2931 participants (2051 from Italy and 880 from Colombia) aged 18 to 35 years old (Mage = 23.85; SDage = 3.63; 67.6% girls). Results: Italian youth were more engaged in risky sexting than Colombian participants, while Colombians indicated being more engaged in non-consensual sexting than Italians. Sexual minority people reported more sharing their own sexts, higher levels of sexting under pressure, and 3.2 times more risky sexting than exclusively heterosexual counterparts. During the pandemic period, participants sent their own sexts 1.5 times more and were less involved in non-consensual sexting than in the pre-pandemic era. Conclusions: The present research could help understand better the cultural dynamics underlying the differences in sexting behaviors, suggesting the relevance of investigating how sexting behaviors and online at-risk activities have changed since the pandemic started. Policy Implications: Results provide implications for educational and prevention programs to improve young people's awareness of sexting behaviors.

Sexual Self-Concept Differentiation: An Exploratory Analysis of Online and Offline Self-Perspectives.

Self-concept differentiation (SCD) has been of interest to researchers, mainly as a structural concept indicative of social specialization or self-concept fragmentation. Nevertheless, this aspect of self-representation has not been studied in regard to sexuality and the extent to which the sexual self may vary across different roles or situations. With the emergence of the Internet, people found new opportunities to explore and express aspects of their sexuality in multiple online scenes, thus increasing the complexity of human sexual experience and expanding the reach of sexual identity. The aim of this study is to investigate SCD in relation to the sexual self-concept, as experienced in the online and offline environments, and its effects on sexual identity, sexual satisfaction and online sexual behaviors. Data analysis pointed towards a fragmented self-view with high degrees of differentiation between the online and offline sexual self-instances being linked to a weaker sense of sexual identity, less sexual satisfaction in real life and less partnered online interactions. However, there were some indications that these relationships were influenced by how people perceive themselves sexually in one instance compared to the other. The results obtained in this study encourage further research on SCD as an important factor in understanding the real-world consequences of online sexual expression.

Effectiveness of Online Versus Telephone Counseling of Rational-Emotional-Behavioral Therapy on Sexual Function of Women Undergoing Cardiac Rehabilitation: A Randomized Clinical Trial:.

Background:Sexual function in patients with cardiovascular disease (CVDs) is often associated with anxiety and irrational beliefs. Moreover, 60-78% of patients with CVDs report sexual problems. Some studies suggest that sexual counseling is necessary for these patients but is not usually provided for them. Online or telephone counseling may be helpful during the covid-19 pandemic, but studies on its application to sexual function appear to be limited. This study aimed to investigate the effectiveness of online vs. telephone counseling of rational-emotional-behavioral therapy (REBT) on the sexual function of women undergoing cardiac rehabilitation. Materials and Methods: In this randomized clinical trial study, 46 women diagnosed with CVDs under rehabilitation were assigned into online and telephone groups. Overall, eight 60-min intervention sessions were held (once a week). The Female's Sexual Function Index (FSFI) questionnaire was completed by the women at baseline, week 8th, and follow-up week 12th (main outcome). Results: FSFI scores between the two groups at baseline (online: 13.28±2, telephone: 12.68±1.52, P=0.254) compared to week 12th (online 28.86±2.44, telephone, 26.6±2.10, P=0.002) were significantly different. As for within-group comparison in baseline compared to week 12th statistically significant difference was observed in all subscales of FSFI (P=0.05). Conclusion: Online and telephone REBT counseling can improve the sexual function of women undergoing cardiac rehabilitation, but online counseling appears to be more effective. Thus, this method is recommended to improve the sexual function of these women during the covid-19 pandemic. [GMJ.2022;11:e2396].