High-Coupled Magnetic-Levitation Hybrid Nanogenerator with Frequency Multiplication Effect for Wireless Water Level Alarm.

Hybrid nanogenerators (HNGs) represent a promising avenue for water energy harvesting, yet their commercial viability faces hurdles such as limited power output, poor coupling, and constrained operational lifespans. Here, a highly coupled triboelectric-electromagnetic magnetic-levitation hybrid nanogenerator (ML-HNG) is introduced that shows great potential for water energy harvesting. The ML-HNG fulfills the challenges of high power output, strong coupling, and long operational lifespans. During the contact-separation process of the triboelectric nanogenerator (TENG), the changing magnetic flux in the electromagnetic generator's coils generates a potential difference between the coils and Cu electrodes. The unique design of the ML-HNG employs a shared coil electrode configuration, which enhances the coupling without adding extra volume. This integration allows the ML-HNG to achieve multi-frequency vibrations and multiple output cycles per external longitudinal movement, a phenomenon known as the frequency multiplication effect. With an average power density of 1.69 W m-3 in water, the ML-HNG provides continuous power for a thermo-hygrometer and can quickly drive a wireless water level alarm system within a minute. This groundbreaking hybrid nanogenerator design holds significant promise for the efficient and consistent harvesting of low-frequency ocean wave energy, marking a substantial advancement in blue energy technology.

MagnetoShield: A Novel Open-Source Magnetic Levitation Benchmark Device for Mechatronics Education and Research.

This article presents an open-source device illustrating the well-known magnetic levitation experiment. The uniqueness of this particular device lies in its exceptionally small dimensions, affordability and availability, which makes it a perfect design for take-home experiments for education but it can also serve as a referential design for testing various control algorithms in research. In addition, this paper provides a comprehensive hardware design for reproducibility along with the detailed derivation of the mathematical model, system identification and validation. Moreover, the introduced hardware comes with an easy-to-use open-source application programming interface in C/C++ for the Arduino IDE, Simulink and CircuitPython. REXYGEN, another environment similar to Simulink, had also been used to demonstrate the capabilities of the MagnetoShield.

Optimal Control for a Superconducting Hybrid MagLev Transport System with Multirate Multisensors in a Smart Factory.

Recently, magnetic levitation systems have been applied and studied in various industrial fields. In particular, in-tracktype magnetic levitation conveyor systems are actively studied since they can effectively minimize electromagnetic effects in processes that require a highly clean environment. In this type of system, diverse and multiple sensors are structurally required so that the control performance of an integrated system is primarily governed by the slowest measuring sensor. This paper proposes a multisensor fusion compensator to integrate the outputs obtained from various sensors into one output with the single fastest time rate. Since the state of the system is estimated at a fast time rate, the optimal controller also guarantees fast performance and stability. The computation of electromagnetic fields and the control performance of the considered superconducting hybrid system were analyzed using a computer simulation based on finite element methods.

Five-Year Outcome After Continuous Flow LVAD With Full-Magnetic (HeartMate 3) Versus Hybrid Levitation System (HeartWare): A Propensity-Score Matched Study From an All-Comers Multicentre Registry.

Despite the withdrawal of the HeartWare Ventricular Assist Device (HVAD), hundreds of patients are still supported with this continuous-flow pump, and the long-term management of these patients is still under debate. This study aims to analyse 5 years survival and freedom from major adverse events in patients supported by HVAD and HeartMate3 (HM3). From 2010 to 2022, the MIRAMACS Italian Registry enrolled all-comer patients receiving a LVAD support at seven Cardiac Surgery Centres. Out of 447 LVAD implantation, 214 (47.9%) received HM3 and 233 (52.1%) received HVAD. Cox-regression analysis adjusted for major confounders showed an increased risk for mortality (HR 1.5 [1.2-1.9]; p = 0.031), for both ischemic stroke (HR 2.08 [1.06-4.08]; p = 0.033) and haemorrhagic stroke (HR 2.6 [1.3-4.9]; p = 0.005), and for pump thrombosis (HR 25.7 [3.5-188.9]; p < 0.001) in HVAD patients. The propensity-score matching analysis (130 pairs of HVAD vs. HM3) confirmed a significantly lower 5 years survival (81.25% vs. 64.1%; p 0.02), freedom from haemorrhagic stroke (90.5% vs. 70.1%; p < 0.001) and from pump thrombosis (98.5% vs. 74.7%; p < 0.001) in HVAD cohort. Although similar perioperative outcome, patients implanted with HVAD developed a higher risk for mortality, haemorrhagic stroke and thrombosis during 5 years of follow-up compared to HM3 patients.

Corrigendum: Five-Year Outcome After Continuous Flow LVAD With Full-Magnetic (HeartMate 3) Versus Hybrid Levitation System (HeartWare): A Propensity-Score Matched Study From an All-Comers Multicentre Registry.

[This corrects the article DOI: 10.3389/ti.2023.11675.].

Applications and sensory utilizations of magnetic levitation in 3D cell culture for tissue Engineering.

3D cell culture approaches are cell culture methods that provide good visualization of interactions between cells while preserving the natural growth pattern. In recent years, several studies have managed to implement magnetic levitation technology on 3D cell culture applications by either combining cells with magnetic nanoparticles (positive magnetophoresis) or applying a magnetic field directly to the cells in a high-intensity medium (negative magnetophoresis). The positive magnetophoresis technique consists of integrating magnetic nanoparticles into the cells, while the negative magnetophoresis technique consists of levitating the cells without labelling them with magnetic nanoparticles. Magnetic levitation methods can be used to manipulate 3D culture, provide more complex habitats and custom control, or display density data as a sensor.The present review aims to show the advantages, limitations, and promises of magnetic 3D cell culture, along with its application methods, tools, and capabilities as a density sensor. In this context, the promising magnetic levitation technique on 3D cell cultures could be fully utilized in further studies with precise control.

Design Methodology for a Magnetic Levitation System Based on a New Multi-Objective Optimization Algorithm.

Multi-objective (MO) optimization is a developing technique for increasing closed-loop performance and robustness. However, its applications to control engineering mostly concern first or second order approximation models. This article proposes a novel MO algorithm, suitable for the design and control of mechanical systems, which does not require any order reduction techniques. The controller parameters are determined directly from a special type of rapid analysis of simulated transient responses. The case study presented in this article consists of a magnetic levitation system. Certain difficulties such as the nonlinearity identification of the magnetic force and duo magnetic field sensor scheme were addressed. To point out the advantages of using the developed approach, the simulations as well as the experiments performed with the help of the created algorithm were compared to those made with common MO algorithms.

Physical Structure Expression for Dense Point Clouds of Magnetic Levitation Image Data.

The research and development of an intelligent magnetic levitation transportation system has become an important research branch of the current intelligent transportation system (ITS), which can provide technical support for state-of-the-art fields such as intelligent magnetic levitation digital twin. First, we applied unmanned aerial vehicle oblique photography technology to acquire the magnetic levitation track image data and preprocessed them. Then, we extracted the image features and matched them based on the incremental structure from motion (SFM) algorithm, recovered the camera pose parameters of the image data and the 3D scene structure information of key points, and optimized the bundle adjustment to output 3D magnetic levitation sparse point clouds. Then, we applied multiview stereo (MVS) vision technology to estimate the depth map and normal map information. Finally, we extracted the output of the dense point clouds that can precisely express the physical structure of the magnetic levitation track, such as turnout, turning, linear structures, etc. By comparing the dense point clouds model with the traditional building information model, experiments verified that the magnetic levitation image 3D reconstruction system based on the incremental SFM and MVS algorithm has strong robustness and accuracy and can express a variety of physical structures of magnetic levitation track with high accuracy.

A Study on the Control Method of 6-DOF Magnetic Levitation System Using Non-Contact Position Sensors.

Recently, due to the development of semiconductor technology, high-performance memory and digital convergence technology that integrates and implements various functions into one semiconductor chip has been regarded as the next-generation core technology. In the semiconductor manufacturing process, various motors are being applied for automated processes and high product reliability. However, dust and shaft loss due to mechanical friction of a general motor system composed of motor-bearing are problematic for semiconductor wafer processing. In addition, in the edge bread remove (EBR) process after the photoresist application process, a nozzle position control system for removing unnecessary portions of the wafer edge is absolutely necessary. Therefore, in this paper, in order to solve the problems occurring in the semiconductor process, a six-degrees-of-freedom (6-DOF) magnetic levitation system without shaft and bearing was designed for application to the semiconductor process system; and an integrated driving control algorithm for 6-DOF control (levitation, rotation, tilt (Roll-Pitch), X-Y axis movement) using the force of each current component derived through current vector control was proposed. Finally, the 6-DOF magnetic levitation system with the non-contact position sensors was fabricated and the validity of the 6-DOF magnetic levitation control method proposed in this paper was verified through a performance test using a prototype.

Development of Magnetically Levitated Rotary Table for Repetitive Trajectory Tracking.

The magnetic levitation system has been considered as a promising actuator in micromachining areas of study. In order to improve the tracking performance and disturbance rejection of the magnetically levitated rotary table, an iterative learning PID control strategy with disturbance compensation is proposed. The estimated disturbance compensates for the control signals to enhance the active disturbance rejection ability. The iterative learning control is used as a feed-forward unit to further reduce the trajectory tracking error. The convergence and stability of the iterative learning PID with disturbance compensation are analysed. A series of comparative experiments are carried out on the in-house, custom-made, magnetically levitated rotary table, and the experimental results highlight the superiority of the proposed control strategy. The iterative learning PID with disturbance compensation enables the magnetically levitated rotary table to realize good tracking performance with complex external disturbance. The proposed control strategy strengthens the applicability of magnetically levitated systems in the mechanism manufacturing area.

Real-Time Implementation of the Prescribed Performance Tracking Control for Magnetic Levitation Systems.

For magnetic levitation systems subject to dynamical uncertainty and exterior perturbations, we implement a real-time Prescribed Performance Control (PPC). A modified function of Global Fast Terminal Sliding Mode Manifold (GFTSMM) based on the transformed error of the novel PPC is introduced; hence, the error variable quickly converges to the equilibrium point with the prescribed performance, which means that maximum overshoot and steady-state of the controlled errors will be in a knowledge-defined boundary. To enhance the performance of Global Fast Terminal Sliding Mode Control (GFTSMC) and to reduce chattering in the control input, a modified third-order sliding mode observer (MTOSMO) is proposed to estimate the whole uncertainty and external disturbance. The combination of the GFTSMC, PPC, and MTOSMO generates a novel solution ensuring a finite-time stable position of the controlled ball and the possibility of performing different orbit tracking missions with an impressive performance in terms of tracking accuracy, fast convergence, stabilization, and chattering reduction. It also possesses a simple design that is suitable for real-time applications. By using the Lyapunov-based method, the stable evidence of the developed method is fully verified. We implement a simulation and an experiment on the laboratory magnetic levitation model to demonstrate the improved performance of the developed control system.

Magnetic-Based Human Tissue 3D Cell Culture: A Systematic Review.

Cell-based assays, conducted on monolayer (2D) cultured cells, are an unquestionably valuable tool for biomedical research. However, three-dimensional (3D) cell culture models have gained relevance over the last few years due to the advantages of better mimicking the microenvironment and tissue microarchitecture in vivo. Recent magnetic-based 3D (m3D) cell culture systems can be used for this purpose. These systems are based on exposing magnetized cells to magnetic fields by levitation, bioprinting, or ring formation to promote cell aggregation into 3D structures. However, the successful development of these structures is dependent on several methodological characteristics and can be applied to mimic different human tissues. Thus, a systematic review was performed using Medline (via Pubmed), Scopus, and Web of Science (until February 2022) databases to aggregate studies using m3D culture in which human tissues were mimicked. The search generated 3784 records, of which 25 met the inclusion criteria. The usability of these m3D systems for the development of homotypic or heterotypic spheroids with or without scaffolds was explored in these studies. We also explore methodological differences specifically related to the magnetic method. Generally, the development of m3D cultures has been increasing, with bioprinting and levitation systems being the most used to generate homotypic or heterotypic cultures, mainly to mimic the physiology of human tissues, but also to perform therapeutic screening. This systematic review showed that there are areas of research where the application of this method remains barely explored, such as cancer research.

Levitated Micromagnets in Superconducting Traps: A New Platform for Tabletop Fundamental Physics Experiments.

Magnetically levitated microparticles have been proposed as mechanical sensors with extreme sensitivity. In particular, micromagnets levitated above a superconductor can achieve very low levels of dissipation and thermal noise. In this paper, we review recent initial experiments and discuss the potential for using these systems as sensors of magnetic fields and rotational motion, as well as possible applications to fundamental physics.

Magnetic levitation assisted biofabrication, culture, and manipulation of 3D cellular structures using a ring magnet based setup.

Diamagnetic levitation is an emerging technology for remote manipulation of cells in cell and tissue level applications. Low-cost magnetic levitation configurations using permanent magnets are commonly composed of a culture chamber physically sandwiched between two block magnets that limit working volume and applicability. This work describes a single ring magnet-based magnetic levitation system to eliminate physical limitations for biofabrication. Developed configuration utilizes sample culture volume for construct size manipulation and long-term maintenance. Furthermore, our configuration enables convenient transfer of liquid or solid phases during the levitation. Before biofabrication, we first calibrated/ the platform for levitation with polymeric beads, considering the single cell density range of viable cells. By taking advantage of magnetic focusing and cellular self-assembly, millimeter-sized 3D structures were formed and maintained in the system allowing easy and on-site intervention in cell culture with an open operational space. We demonstrated that the levitation protocol could be adapted for levitation of various cell types (i.e., stem cell, adipocyte and cancer cell) representing cells of different densities by modifying the paramagnetic ion concentration that could be also reduced by manipulating the density of the medium. This technique allowed the manipulation and merging of separately formed 3D biological units, as well as the hybrid biofabrication with biopolymers. In conclusion, we believe that this platform will serve as an important tool in broad fields such as bottom-up tissue engineering, drug discovery and developmental biology.

Scaffold-free biofabrication of adipocyte structures with magnetic levitation.

Tissue engineering research aims to repair the form and/or function of impaired tissues. Tissue engineering studies mostly rely on scaffold-based techniques. However, these techniques have certain challenges, such as the selection of proper scaffold material, including mechanical properties, sterilization, and fabrication processes. As an alternative, we propose a novel scaffold-free adipose tissue biofabrication technique based on magnetic levitation. In this study, a label-free magnetic levitation technique was used to form three-dimensional (3D) scaffold-free adipocyte structures with various fabrication strategies in a microcapillary-based setup. Adipogenic-differentiated 7F2 cells and growth D1 ORL UVA stem cells were used as model cells. The morphological properties of the 3D structures of single and cocultured cells were analyzed. The developed procedure leads to the formation of different patterns of single and cocultured adipocytes without a scaffold. Our results indicated that adipocytes formed loose structures while growth cells were tightly packed during 3D culture in the magnetic levitation platform. This system has potential for ex vivo modeling of adipose tissue for drug testing and transplantation applications for cell therapy in soft tissue damage. Also, it will be possible to extend this technique to other cell and tissue types.

Emerging Biomolecular Testing to Assess the Risk of Mortality from COVID-19 Infection.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 and COVID-19) has produced an unprecedented global pandemic. Though the death rate from COVID-19 infection is ∼2%, many infected people recover at home. Among patients for whom COVID-19 is deadly are those with pre-existing comorbidities. Therefore, identification of populations at highest risk of COVID-19 mortality could significantly improve the capacity of healthcare providers to take early action and minimize the possibility of overwhelming care centers, which in turn would save many lives. Although several approaches have been used/developed (or are being developed/suggested) to diagnose COVID-19 infection, no approach is available/proposed for fast diagnosis of COVID-19 infections likely to be fatal. The central aim of this short perspective is to suggest a few possible nanobased technologies (i.e., protein corona sensor array and magnetic levitation) that could discriminate COVID-19-infected people while still in the early stages of infection who are at high risk of death. Such discrimination technologies would not only be useful in protecting health care centers from becoming overwhelmed but would also provide a powerful tool to better control possible future pandemics with a less social and economic burden.

Design and implementation of a novel interior permanent magnet bearingless slice motor.

In this paper, we present a bearingless motor with a novel segmented dipole interior permanent magnet (IPM) slice rotor. The segmented dipole IPM rotor contains a unique pattern of interior permanent magnets arranged to generate a dipole air gap flux pattern. The magnets are encapsulated within an electrical steel rotor structure. The stator contains a three-phase, four-pole winding for suspension and a three-phase, two-pole winding for rotation. We present analyses of several candidate rotor designs. The analyses indicate that the segmented dipole IPM rotor achieves a reduced trade-off between force and torque capacity and relatively symmetric force dynamics as compared to prior art designs and alternate topologies. Symmetric and decoupled force dynamics allow a simple force decoupling algorithm to be used. We designed, constructed, and tested a prototype system. We experimentally demonstrate that the prototype system can achieve stable levitation and open-loop rotation.

An In Vitro Model of Nonattached Biofilm-Like Bacterial Aggregates Based on Magnetic Levitation.

Chronic infections are associated with the formation of nonattached biofilm-like aggregates. In vitro models of surface-attached biofilms do not always accurately mimic these processes. Here, we tested a new approach to create in vitro nonattached bacterial aggregates using the principle of magnetic levitation of biological objects placed into a magnetic field gradient. Bacteria grown under magnetic levitation conditions formed nonattached aggregates that were studied with confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM) and characterized quantitatively. Nonattached aggregates consisted of bacteria submerged into an extracellular matrix and demonstrated features characteristic of biofilms, such as a polymeric matrix that binds Ruby Red and Congo red dyes, a prerequisite of bacterial growth, and increased resistance to gentamicin. Three quantitative parameters were explored to characterize strain-specific potential to form nonattached aggregates: geometric sizes, relative quantities of aggregated and free-swimming bacteria, and Congo red binding. Among three tested Escherichia coli strains, one strain formed nonattached aggregates poorly, and for this strain, all three of the considered parameters were different from those of the other two strains (P < 0.05). Further, we characterized biofilm formation on plastic and agar surfaces by these strains and found that good biofilm formation ability does not necessarily indicate good nonattached aggregate formation ability, and vice versa. The model and quantitative methods can be applied for in vitro studies of nonattached aggregates and modeling bacterial behavior in chronic infections, as it is important to increase our understanding of the role that nonattached bacterial aggregates play in the pathogenesis of chronic diseases.IMPORTANCE An increasing amount of evidence indicates that chronic infections are associated with nonattached biofilm-like aggregates formed by pathogenic bacteria. These aggregates differ from biofilms because they form under low-shear conditions within the volume of biological fluids and they do not attach to surfaces. Here, we describe an in vitro model that provides nonattached aggregate formation within the liquid volume due to magnetic levitation. Using this model, we demonstrated that despite morphological and functional similarities of nonattached aggregates and biofilms, strains that exhibit good biofilm formation might exhibit poor nonattached aggregate formation, suggesting that mechanisms underlying the formation of biofilms and nonattached aggregates are not identical. The magnetic levitation approach can be useful for in vitro studies of nonattached aggregate formation and simulation of bacterial behavior in chronic infections.

Magnetic Levitation in Chemistry, Materials Science, and Biochemistry.

All matter has density. The recorded uses of density to characterize matter date back to as early as ca. 250 BC, when Archimedes was believed to have solved "The Puzzle of The King's Crown" using density.[1] Today, measurements of density are used to separate and characterize a range of materials (including cells and organisms), and their chemical and/or physical changes in time and space. This Review describes a density-based technique-magnetic levitation (which we call "MagLev" for simplicity)-developed and used to solve problems in the fields of chemistry, materials science, and biochemistry. MagLev has two principal characteristics-simplicity, and applicability to a wide range of materials-that make it useful for a number of applications (for example, characterization of materials, quality control of manufactured plastic parts, self-assembly of objects in 3D, separation of different types of biological cells, and bioanalyses). Its simplicity and breadth of applications also enable its use in low-resource settings (for example-in economically developing regions-in evaluating water/food quality, and in diagnosing disease).

Application and Optimization of Wavelet Transform Filter for North-Seeking Gyroscope Sensor Exposed to Vibration.

Conventional wavelet transform (WT) filters have less effect on de-noising and correction of a north-seeking gyroscope sensor exposed to vibration, since the optimal wavelet decomposed level for de-noising is difficult to determine. To solve this problem, this paper proposes an optimized WT filter which is suited to the magnetic levitation gyroscope (GAT). The proposed method was tested on an equivalent mock-up network of the tunnels associated with the Hong Kong‒Zhuhai‒Macau Bridge. The gyro-observed signals exposed to vibration were collected in our experiment, and the empirical values of the optimal wavelet decomposed levels (from 6 to 10) for observed signals were constrained and validated by the high-precision Global Navigation Satellite System (GNSS) network. The result shows that the lateral breakthrough error of the tunnel was reduced from 12.1 to 3.8 mm with a ratio of 68.7%, which suggests that the method is able to correct the abnormal signal of a north-seeking gyroscope sensor exposed to vibration.