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1.
Clin Case Rep ; 11(3): e7019, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36879676

RESUMO

Necrobiosis Lipoidica (NL) is a rare granulomatous skin condition typically occurring in lower extremities. We report an atypical case of NL, and we highlight the role of dermoscopy in the diagnostic approach.

2.
Diseases ; 11(3)2023 Aug 18.
Artigo em Inglês | MEDLINE | ID: mdl-37606477

RESUMO

Diabetes mellitus (DM) is one of the world's most important health problems, affecting more than half a billion of the world's population today, with an ever-increasing prevalence. Among the most common manifestations of diabetes are skin manifestations, with 30-70% of patients experiencing skin complications during the course of the disease. Conditions such as acanthosis nigricans, diabetic dermopathy, necrobiosis lipoidica, bacterial infections, fungal infections, skin xerosis, and metabolic prurigo are often associated with diabetes and often precede its diagnosis. We conducted a retrospective study on a group of 103 patients hospitalized between January 2018 and December 2022, in a clinic of a county hospital, using as criteria the diagnosis of diabetes mellitus complicated by cutaneous manifestations frequently associated with diabetes. The aim was to observe which are the most common manifestations and whether they correlate with data in the research literature. In the present study, manifestations such as diabetic foot (20% of patients), bacterial (35%) and fungal infections, and cutaneous xerosis (45%) were predominant. Often, the integumentary involvement may precede the diagnosis of the underlying disease. It is therefore very important to recognize, investigate and treat these manifestations as soon as possible.

3.
Rev. cuba. endocrinol ; 27(1): 0-0, ene.-abr. 2016. ilus
Artigo em Espanhol | LILACS | ID: lil-780726

RESUMO

La necrobiosis lipoidica es una dermatosis poco frecuente, de origen desconocido. Puede observarse en pacientes sin alteración de la glucosa, pero frecuentemente está asociada a la diabetes mellitus bien establecida. Menos común es que estas lesiones en la piel aparezcan en estadios prediabéticos. Se describe el caso de una paciente femenina, de 65 años de edad, que hace 10 años comenzó a presentar una lesión papuloeritematosa de 1 cm, con bordes bien definidos, en la cara lateral interna de la pierna derecha. Recientemente le realizan biopsia de la lesión dermatológica y prueba de tolerancia a la glucosa oral, y se diagnostica necrobiosis lipoidica y tolerancia a la glucosa alterada respectivamente. Se piensa que los pacientes con esta enfermedad deben tener seguimiento a largo plazo, para diagnosticar oportunamente diabetes mellitus u otros estados prediabéticos(AU)


Necrobiosis lipoidica is a rare dermatosis of unknown origin. It can be observed in patients with unaltered glucose indexes but frequently associated to well-established diabetes mellitus. It is even less common that this type of skin lesions occur in pre-diabetic staging. This is the case of 65 years-old woman, who had presented 1 cm-long papulloerythematous lesion with well-defined contours for 10 years in the inner lateral side of her right leg. She had been recently biopsied in her cutaneous lesion and made a glucose-tolerance test, which yielded necrobiosis lipoidica and altered glucose tolerance. It is considered that the patients with this disease should be followed-up for a long period to timely diagnose diabetes mellitus or other pre-diabetic conditions(AU)


Assuntos
Humanos , Feminino , Idoso , Biópsia/estatística & dados numéricos , Diabetes Mellitus/diagnóstico , Necrobiose Lipoídica/diagnóstico , Estado Pré-Diabético , Pele/lesões
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