Overlapping representations of observed actions and action-related features.

The lateral occipitotemporal cortex (LOTC) has been shown to capture the representational structure of a smaller range of actions. In the current study, we carried out an fMRI experiment in which we presented human participants with images depicting 100 different actions and used representational similarity analysis (RSA) to determine which brain regions capture the semantic action space established using judgments of action similarity. Moreover, to determine the contribution of a wide range of action-related features to the neural representation of the semantic action space we constructed an action feature model on the basis of ratings of 44 different features. We found that the semantic action space model and the action feature model are best captured by overlapping activation patterns in bilateral LOTC and ventral occipitotemporal cortex (VOTC). An RSA on eight dimensions resulting from principal component analysis carried out on the action feature model revealed partly overlapping representations within bilateral LOTC, VOTC, and the parietal lobe. Our results suggest spatially overlapping representations of the semantic action space of a wide range of actions and the corresponding action-related features. Together, our results add to our understanding of the kind of representations along the LOTC that support action understanding.

Inter-subject alignment of MEG datasets in a common representational space.

Pooling neural imaging data across subjects requires aligning recordings from different subjects. In magnetoencephalography (MEG) recordings, sensors across subjects are poorly correlated both because of differences in the exact location of the sensors, and structural and functional differences in the brains. It is possible to achieve alignment by assuming that the same regions of different brains correspond across subjects. However, this relies on both the assumption that brain anatomy and function are well correlated, and the strong assumptions that go into solving the under-determined inverse problem given the high-dimensional source space. In this article, we investigated an alternative method that bypasses source-localization. Instead, it analyzes the sensor recordings themselves and aligns their temporal signatures across subjects. We used a multivariate approach, multiset canonical correlation analysis (M-CCA), to transform individual subject data to a low-dimensional common representational space. We evaluated the robustness of this approach over a synthetic dataset, by examining the effect of different factors that add to the noise and individual differences in the data. On an MEG dataset, we demonstrated that M-CCA performs better than a method that assumes perfect sensor correspondence and a method that applies source localization. Last, we described how the standard M-CCA algorithm could be further improved with a regularization term that incorporates spatial sensor information. Hum Brain Mapp 38:4287-4301, 2017. © 2017 Wiley Periodicals, Inc.

Dimensions underlying human understanding of the reachable world.

Near-scale environments, like work desks, restaurant place settings or lab benches, are the interface of our hand-based interactions with the world. How are our conceptual representations of these environments organized? What properties distinguish among reachspaces, and why? We obtained 1.25 million similarity judgments on 990 reachspace images, and generated a 30-dimensional embedding which accurately predicts these judgments. Examination of the embedding dimensions revealed key properties underlying these judgments, such as reachspace layout, affordance, and visual appearance. Clustering performed over the embedding revealed four distinct interpretable classes of reachspaces, distinguishing among spaces related to food, electronics, analog activities, and storage or display. Finally, we found that reachspace similarity ratings were better predicted by the function of the spaces than their locations, suggesting that reachspaces are largely conceptualized in terms of the actions they support. Altogether, these results reveal the behaviorally-relevant principles that structure our internal representations of reach-relevant environments.

Flexing the principal gradient of the cerebral cortex to suit changing semantic task demands.

Understanding how thought emerges from the topographical structure of the cerebral cortex is a primary goal of cognitive neuroscience. Recent work has revealed a principal gradient of intrinsic connectivity capturing the separation of sensory-motor cortex from transmodal regions of the default mode network (DMN); this is thought to facilitate memory-guided cognition. However, studies have not explored how this dimension of connectivity changes when conceptual retrieval is controlled to suit the context. We used gradient decomposition of informational connectivity in a semantic association task to establish how the similarity in connectivity across brain regions changes during familiar and more original patterns of retrieval. Multivoxel activation patterns at opposite ends of the principal gradient were more divergent when participants retrieved stronger associations; therefore, when long-term semantic information is sufficient for ongoing cognition, regions supporting heteromodal memory are functionally separated from sensory-motor experience. In contrast, when less related concepts were linked, this dimension of connectivity was reduced in strength as semantic control regions separated from the DMN to generate more flexible and original responses. We also observed fewer dimensions within the neural response towards the apex of the principal gradient when strong associations were retrieved, reflecting less complex or varied neural coding across trials and participants. In this way, the principal gradient explains how semantic cognition is organised in the human cerebral cortex: the separation of DMN from sensory-motor systems is a hallmark of the retrieval of strong conceptual links that are culturally shared.

Independent contributions of the face, body, and gait to the representation of the whole person.

Most studies on person perception have primarily investigated static images of faces. However, real-life person perception also involves the body and often the gait of the whole person. Whereas some studies indicated that the face dominates the representation of the whole person, others have emphasized the additional contribution of the body and gait. Here, we compared models of whole-person perception by asking whether a model that includes the body for static whole-person stimuli and also the gait for dynamic whole-person stimuli accounts better for the representation of the whole person than a model that takes into account the face alone. Participants rated the distinctiveness of static or dynamic displays of different people based on either the whole person, face, body, or gait. By fitting a linear regression model to the representation of the whole person based on the face, body, and gait, we revealed that the face and body contribute uniquely and independently to the representation of the static whole person, and that gait further contributes to the representation of the dynamic person. A complementary analysis examined whether these components are also valid dimensions of a whole-person representational space. This analysis further confirmed that the body in addition to the face as well as the gait are valid dimensions of the static and dynamic whole-person representations, respectively. These data clearly show that whole-person perception goes beyond the face and is significantly influenced by the body and gait.