Perforated peptic ulcer disease in transferred patients is associated with significant increase in length of stay.

BACKGROUND: Perforated peptic ulcer disease (PPUD) has a prevalence of 0.004-0.014% with mortality of 23.5% (Tarasconi et al. in World J Emerg Surg 15(PG-3):3, 2020). In this single center study, we examined the impact associated with patient transfer from outside facilities to our center for definitive surgical intervention (exploratory laparotomy). METHODS: Using EPIC report workbench, we identified 27 patients between 2018 and 2021 undergoing exploratory laparotomy with a concurrent diagnosis of peptic ulcer disease, nine of which were transferred to our institution for care. We queried this population for markers of disease severity including mortality, length of stay, intensive care unit (ICU) length of stay, and readmission rates. Manual chart reviews were performed to examine these outcomes in more detail and identify patients who had been transferred to our facility for surgery from an outside hospital. RESULTS: A total of 27 patients were identified undergoing exploratory laparotomy for definitive treatment of PPUD. The majority of patients queried underwent level A operations, the most urgent level of activation. In our institution, a Level A operation needs to go to the operating room within one hour of arrival to the hospital. Average mortality for this patient population was 14.8%. The readmission rate was 40.1%, and average length of ICU stay post-operatively was 16 days, with 83% of non-transfer patients requiring ICU admission and 100% of transfer patients requiring ICU admission, although this was not found to be statistically significant. Average length of hospital stay was 27 days overall. For non-transfer patients and transfer patients, LOS was 20 days and 41 days, respectively, which was statistically significant by one-sided t-test (p = 0.05). CONCLUSION: Patients transferred for definitive care of PPUD in a population otherwise notable for high mortality and high readmission rates: their average length of stay compared to non-transfer patients was over twice the length, which was statistically significant. Transferred patients also had higher rates of ICU care requirement although this was not statistically significant. Further inquiry to identify modifiable variables to facilitate the care of transferred patients is warranted, especially in the context of improving quality metrics known to enhance patient outcomes, satisfaction, and value.

Navigating Through Surgical Implications of Helicobacter pylori: An Up-to-Date Comprehensive Literature Review.

Helicobacter pylori, a gram-negative bacterium, has been identified as a major contributor to gastrointestinal diseases, ranging from gastritis and peptic ulcers to more severe complications such as gastric adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. While pharmacological eradication therapies have been successful in managing H. pylori-associated diseases, the implications of this bacterium on surgical interventions remain a topic of ongoing research and clinical consideration. This comprehensive review aims to elucidate the intricate surgical implications of H. pylori infection. Recent data on the well-known relationship between and the development of gastroduodenal diseases, including peptic ulcers and gastric cancer, is analyzed. Concurrently, Helicobacter pylori infection may have a role in promoting colonic carcinogenesis and, more interestingly, it has also been linked to biliary tract cancers. The review highlights the evolving landscape of H. pylori management in the context of surgical interventions, accentuating the need for further research to delineate optimal strategies for preoperative screening, eradication therapies, and their impact on surgical outcomes and long-term patient prognosis. Comprehending the surgical ramifications of H. pylori infection remains crucial, emphasizing the significance of interdisciplinary approaches and ongoing research effort aimed at enhancing patient care.

Similar Rates of Symptomatic Marginal Ulcers After One-Anastomosis-Gastric Bypass Compared to Roux-en-Y Gastric Bypass.

PURPOSE: One-anastomosis-gastric-bypass (OAGB) has become a common bariatric procedure worldwide. Marginal ulcers (MU) are a significant non-immediate complication of gastric bypass surgeries. There seems to be concern among surgeons that MU are more common after OAGB compared with Roux-en-Y gastric bypass (RYGB) due to the constant and extensive exposure of the anastomosis to bile. The aim of this study was to compare the incidence, presentation, and management of MU between the two surgeries. MATERIALS AND METHODS: A retrospective study of prospectively collected data was performed to include all consecutive patients between 2010 and 2020, who underwent elective OAGB or RYGB at our institution. Patients diagnosed with symptomatic MU were identified. Factors associated with this complication were assessed and compared between the two surgeries. RESULTS: Symptomatic MU were identified in 23/372 OAGB patients (6.2%) and 35/491 RYGB patients (7.1%) (p = 0.58). Time to ulcer diagnosis was shorter in OAGB patients (12 ± 11 vs. 22 ± 17 months, p < 0.01). Epigastric pain was the common symptom (78% OAGB vs. 88.5% RYGB, p = 0.7) and approximately 15% of ulcers presented with perforation upon admission (17% vs.11.4%, p = 0.7). Re-operation was required in 5/23 OAGB (21.7%) and 6/36 RYGB (17%) patients (p = 0.11) while the rest of the patients were managed non-operatively. CONCLUSIONS: The risk of developing a marginal ulcer is similar between patients who underwent OAGB and RYGB. Patients diagnosed with MU following OAGB tend to present earlier; however, the clinical presentation is similar to RYGB patients. The management of this serious complication seems to be associated with acceptable outcomes with comparable operative and non-operative approaches.

Early Marginal Ulcer After Roux-en-Y Gastric Bypass: MBSAQIP Database Analysis of Trends and Predictive Factors.

PURPOSE: Marginal ulcer (MU) is a known complication after Roux-en-Y gastric bypass (RYGB) that carries significant morbidity. First, we aimed to determine the trends and the rates of readmission, reintervention, and reoperation of 30-day MU. Second, we aim to determine the predictive factors associated with this complication. MATERIALS AND METHODS: Patients who had 30-day marginal ulcer (MU) after LRYGB were identified using the 2015-2021 MBSAQIP database. Those who had a 30-day complication other than MU were excluded. Bivariate and logistic regression analyses were performed. RESULTS: Among 213,104 patients undergoing laparoscopic RYGB, 638 (0.3%) showed 30-day MU. This group of patients required endoscopic interventions, readmissions, and reoperations at rates of 88%, 72%, and 9%, respectively. Predictive factors for 30-day MU after RYGB were renal insufficiency, history of DVT, previous cardiac stent, African American race, chronic steroid use, COPD, therapeutic anticoagulation, anastomotic leak test, GERD, and operative time > 120 min. Additionally, patients who had 30-day MU showed significantly higher rates of overall complications such as pulmonary, cardiac and renal complications, unplanned ICU admission, blood transfusions, venous thromboembolism (VTE), and non-home discharge (p < 0.05). The MU group showed similar rates of 30-day mortality as those without this complication (0.2% vs 0.1%, p = 0.587). CONCLUSIONS: The incidence of 30-day MU following RYGB was 0.3%. Patients with MU required endoscopic interventions, readmissions, and reoperations at rates of 88%, 72%, and 9%, respectively. Some preoperative and intraoperative factors contributed to an increased risk of 30-day MU.

Utilidad de las escalas Rockall y Baylor modificado en hemorragia digestiva alta por úlcera péptica / Usefulness of the Modified Rockall and Baylor Scores in Gastrointestinal Hemorrhage due to Peptic Ulcer

Introducción: la hemorragia digestiva alta constituye un problema de salud frecuente en todo el mundo y es una de las urgencias que determina gran número de ingresos en los servicios de Cirugía General en nuestro medio, por lo que reviste gran importancia clínica y sanitaria. Objetivo: determinar la utilidad de las escalas de Rockall y Baylor modificado para pronosticar resangrado en pacientes con hemorragia digestiva alta. Método: se realizó un estudio observacional descriptivo prospectivo, incluyendo a los pacientes ingresados por hemorragia digestiva alta por úlcera péptica en el Hospital Enrique Cabrera, desde el 1ro. de enero del 2012 hasta el 30 de septiembre del 2015. Resultados: de 300 pacientes ingresados por hemorragia digestiva alta por úlcera péptica, se tomó una muestra de 71 enfermos. El tratamiento endoscópico se realizó a todos los pacientes, y el tratamiento quirúrgico en 8,4 por ciento. Nueve pacientes presentaron resangrado (12,7 por ciento). Las escalas de Rockall y Baylor modificado presentaron una especificidad de 82 por ciento y 86 por ciento, respectivamente con baja sensibilidad en ambos casos a pesar de esto la escala de Rockall es la de mayor sensibilidad. Conclusiones: las dos escalas fueron altamente específicas, pero la de Rockall fue más sensible para identificar los pacientes con riesgo alto de resangrado(AU)

Introduction: Upper gastrointestinal hemorrhage is a common health problem worldwide and one of the emergencies determining a huge number of admissions into general surgery services in our scenario, it is therefore of great clinical and sanitary importance. Objective: To determine the usefulness of the modified Rockall and Baylor scores in predicting rebleeding in patients with upper gastrointestinal hemorrhage. Method: A prospective, descriptive, observational study was carried out, including patients admitted for upper gastrointestinal hemorrhage due to peptic ulcer in Enrique Cabrera, from January 1st, 2015 to September 30, 2015. Results: Among the 300 patients admitted for upper digestive hemorrhage due to peptic ulcer, we took a sample of 71 patients. All patients were performed endoscopic treatment, while 8.4 percent were performed surgical treatment. Nine patients presented with rebleeding (12.7 percent). The modified Rockall and Baylor scores showed a specificity of 82 percent and 86 percent, respectively, with low sensitivity in both cases. Despite this, the Rockall score is the one with the highest sensitivity. Conclusions: The two score were highly specific, but the Rockall score was more sensitive for identifying patients at high risk of rebleeding(AU)

Evolução histórica da úlcera péptica: da etiologia ao tratamento / History of peptic ulcer: from etiology to treatment

Objetivos: revisar os principais aspectos históricos da progressão do conhecimento sobre a etiologia da úlcera péptica e das terapêuticas clínicas e cirúrgicas empregadas no tratamento desta enfermidade.Fonte de dados: revisão bibliográfica através do PubMed. Foram analisados artigos selecionados sobre a história da úlcera péptica.Síntese dos dados: durante décadas, cirurgiões acreditaram que a doença da úlcera péptica era causada pelo excesso de ácido. O aforisma ?sem ácido, sem úlcera? foi enraizado em todos os residentes de cirurgia, e todos os esforços foram concentrados em eliminar o ácido através de uma operação. Com o advento da terapêutica farmacológica, houve melhora no sucesso do tratamento clínico e o número de casos cirúrgicos diminuiu. Com a descoberta do Helicobacter pylori, ainda mais pacientes foram tratados clinicamente e o número de casos cirúrgicos diminuiu novamente, persistindo apenas para casos refratários, hemorragia ou perfuração.Conclusões: úlcera péptica é uma doença reconhecida desde a antiguidade. A compreensão da evolução gradual das várias formas de seu tratamento serve de alerta e ensinamento de como evolui o conhecimento científico, onde as certezas efinitivas podem ser alteradas por inovações e resultados de pesquisas metodologicamente bem delineadas e realizadas, bem como elucidar a difícil trajetória que tem sido percorrida para poder solucionar o sofrimento dos pacientes que possuem essa enfermidade.

Aims: To review the main aspects of the historical progression of knowledge about the etiology of peptic ulcer and the clinical and surgical treatment used in the treatment of this disease.Source of data: A search was carried out at PubMed. Selected papers about the history of the peptic ulcer were reviewed.Summary of findings: For decades, surgeons were taught and believed that peptic ulcer disease was caused by acid.The dictum ?no acid, no ulcer? was engrained into every resident of surgery, and all efforts were focused on eliminating acid through operation. With the advent of pharmacological therapy, more ulcers were successfully treated medically and the number of surgical cases decreased. With the discovery of Helicobacter pylori, even more patients were successfully treated medically and the number of surgical cases decreased again, usually only to include refractory cases, hemorrhage or perforation.Conclusions: Peptic ulcer is a disease recognized since ancient times. The understanding of the gradual evolution of several forms of treatment serves as a warning and teaching of how scientific knowledge evolves, where the final certainties can be changed by innovations and research findings methodologically well designed and executed, and to clarify the difficult path that has been traversed in order to solve the suffering of patients who have this disease.

Cirugía exerética en la úlcera péptica complicada: ¿procedimiento extemporáneo? / Exeretic surgery in complicated peptic ulcer: An inopportune procedure?

INTRODUCCIÓN. El objetivo del presente estudio fue analizar los resultados del tratamiento quirúrgico en la enfermedad ulceropéptica crónica gástrica o duodenal complicada, durante un período de 15 años. MÉTODOS. Se realizó un estudio descriptivo y retrospectivo de los pacientes con enfermedad ulceropéptica complicada tratados mediante exéresis. Los pacientes (45 en total) fueron atendidos por alguno de los autores, en el Hospital Provincial Clinicoquirúrgico Amalia Simoni, en Camagüey, entre enero de l989 y diciembre del 2004. RESULTADOS. La enfermedad se presentó con mayor frecuencia en el sexo masculino (82,22 por ciento) y en las edades comprendidas entre 36 y 50 años (46,67 por ciento). El 95,56 por ciento de los pacientes tratados padecían úlcera duodenal, y la principal indicación para la cirugía fue la intratabilidad (62,22 por ciento). La endoscopia (84,44 por ciento) resultó ser muy útil para el diagnóstico de esta afección. A todos los operados se le realizó vagotomía con antrectomía; en el 68,89 por ciento la anastomosis fue de Billroth II, y en el resto de los pacientes (31,11 por ciento) fue del tipo Billroth I. Se observó igual cantidad de complicaciones precoces en las técnicas realizadas, y entre ellas prevalecieron el sangrado de la anastomosis y el retardo de la evacuación. Se detectaron más complicaciones tardías en la anastomosis de tipo Billroth II que en la de Billroth I. Los resultados quirúrgicos fueron excelentes y muy buenos en el 89 por ciento de los casos. La variante antecólica registró el mayor porcentaje de resultados no satisfactorios (9,09 por ciento). Solo en dos pacientes se obtuvieron resultados malos, aunque no hubo mortalidad operatoria. CONCLUSIONES. Este tipo de cirugía tiene indicación solo en casos de úlcera péptica complicada. No es el método de elección en pacientes ulcerosos, pero su uso requiere conocer las diferentes técnicas y saber utilizarlas. No es por tanto un procedimiento que deba olvidarse(AU)

INTRODUCTION: The aim of present study was to analyze the surgical treatment results in the complicated duodenal or gastric chronic peptic ulcer over 15 years. METHODS: A retrospective and descriptive study was conducted in patients presenting with complicated peptic ulcer by exeresis. Patients (n=45) were seen by some of us in the Amalia Simoni Clinical Surgical of Camaguey province from January, 1989 to December, 2004. RESULTS: Disease was more frequent in male sex (82,22 percent) and in ages from 36 to 50 years (46,67 percent). The 95,56 percent of patients treated suffered from duodenal ulcer and the main criterion for surgery was its unmanageable condition (62,22 percent). Endoscopy was very useful for diagnosis of this entity. All operated on underwent vagotomy with antrectomy; in the 68,89 percent we performed a Billroth's II anastomosis and in remainder (31,11 percent it was of Billroth I type. There was a similar figure of early complications related to techniques used and among them prevails the anastomosis bleeding and delay evacuation. There were more late complications in type Billroth II anastomosis than in the Billroth I. Surgical results were excellent and very good in the 89 percent of cases. The enterocolitis variant has the great percentage of non-satisfactory results (9,09 percent). Only two patients had poor results, although there wasn't operative mortality. CONCLUSIONS: This kind of surgery is indicated only in cases of complicated peptic ulcer. It is not the choice method in ulcer patients, but in its use it is necessary to know about different techniques and its use. Thus, we must to know a lot about this procedure(AU)

Sangrado digestivo alto: consideraciones actuales acerca de su diagnóstico y tratamiento / Upper digestive bleeding: current considerations about its diagnosis and treatment

Introducción: El sangrado digestivo alto es una emergencia medicoquirúrgica frecuente, que suele ser diagnosticado mediante la endoscopia por vía oral y la radiografía de esófago, estómago y duodeno. Objetivo: Describir los resultados diagnósticos y terapéuticos en los pacientes ingresados por esa causa en el Servicio de Cirugía General del Hospital General Docente Dr Juan Bruno Zayas Alfonso de Santiago de Cuba durante el bienio 2007-2008. Métodos: Se hizo un estudio descriptivo, transversal y retrospectivo de 88 pacientes hospitalizados con esa afección, tomando en cuenta variables seleccionadas. Resultados: La endoscopia por vía oral se efectuó a 56,8 por ciento de la serie y reveló que tanto la úlcera duodenal como las gastritis agudas y crónicas fueron las gastropatías predominantes según clasificación de Forrest III; en la radiografía de esófago, estómago y duodeno se observaron más comúnmente los pliegues engrosados. Excepto 6 pacientes (6,8 por ciento) que fallecieron, los restantes mejoraron con el tratamiento durante una corta estadía. Conclusiones: A pesar de la efectividad de la prueba endoscópica, aún no puede realizarse a todas las personas con sangrado digestivo alto.

ntroduction: The upper digestive bleeding is a frequent medical surgical emergency that is usually diagnosed by means of oral endoscopy and the esophagus, stomach and duodenum x-ray. Objective: To describe the diagnostic and therapeutic results in the patients admitted by that cause in the General Surgery Service of Dr Juan Bruno Zayas Alfonso Teaching General Hospital in Santiago de Cuba during the biennium 2007-2008. Methods: A descriptive, cross-sectional and retrospective study of 88 patients hospitalized with that affection was carried out, taking into account selected variables. Results: The oral endoscopy was made to 56,8 per cent of patients of the series and revealed that both duodenal ulcer and acute and chronic gastritis were the predominant gastropathies according to classification of Forrest III. In the esophagus, stomach and duodenum x-ray thickened folds were the most commonly observed. Except for 6 patients (6,8 per cent) who died, the rest of them improved with the treatment during a short stay. Conclusions: In spite of the effectiveness of the endoscopic test, it cannot still be made to all the people with upper digestive bleeding.

Ten-years comparative study after surgical treatment of perforated peptic ulcer according to ulcer relapse between H. Pylori positive, after eradication, and negative patients / Estudo comparativo quanto à recidiva ulcerosa do tratamento cirúrgico de úlcera péptica perfurada entre pacientes H. Pylori positivos, após erradicação, e negativos

BACKGROUND: The surgical treatment for perforated peptic ulcer is still a matter of discussion. The surgeons, for many years, made their options between acid-reducing procedures with some morbi-mortality and simpler procedures like closure of the perforation. But, in these cases, were faced with a high chance of ulcer relapse. Since the proved link between peptic ulcer and gastroduodenal infection caused by H. pylori, a recommendation for a change in their attitudes going back to simpler procedures with eradication of the bacteria was done.AIM: To analyse ulcer recurrence in patients treated with the same surgical procedure but belonging to two different groups: positive and negative to H. pilori.METHODS: A total of 144 patients were treated with simple closure of their perforated pre-pyloric, pyloric and duodenal ulcers. Thirty days after operation they were submitted to upper endoscopy and tested for the bacteria by urease and histopathological exams and divided into two groups according to the results of the tests: positive and negative. The positive ones were eradicated and, together with the negative group, were followed through six months interval endoscopies and detection tests looking for ulcer relapses and reinfection in the eradicated group. The positive group consisted of 25 patients, with two patients considered non eradicable according to the treatment protocol. They were followed for an average period of 38,21 months.RESULTS: Relapse was detected in four patients (17,39%), half of them (8,69%) were reinfected. The negative group consisted of 26 patients, with a median follow-up of 38,28 months and eight (30,76%) relapses were detected. There was no statistical significant difference due probably to the high dropout of patients.CONCLUSION: Simple suture with H. pilori eradication is the gold standard for the positive group, leaving the question of acid-reducing procedures open for the negative ones.

RACIONAL: O tratamento cirúrgico da úlcera péptica perfurada é assunto discutível. Os cirurgiões, por muitos anos, fizeram suas opções entre procedimentos de redução ácida, somente fechamento da perfuração - porém com maior chance de recidiva ulcerosa. Desde a comprovada vinculação da úlcera péptica e suas complicações à infecção gastroduodenal causada pelo Helicobacter pylori, houve recomendação para mudança na atitude dos cirurgiões na volta à operação mais simples com erradicação da bactéria.OBJETIVO: Analisar a recidiva ulcerosa em pacientes com úlcera perfurada H. pylori positiva que foram submetidos à simples sutura da lesão e omentopexia com erradicação da bactéria e compará-la com H. pylori negativo submetido ao mesmo tratamento cirúrgico.MÉTODOS: Cento e quatorze pacientes com úlceras pré-pilóricas, pilóricas e duodenais perfuradas foram atendidos com fechamento simples. Trinta dias após a operação submeteram-se à endoscopia digestiva alta com biópsias para testes da urease e histopatológicos. Foram divididos em dois grupos de acordo com o resultado dos testes: positivo e negativo.Os positivos foram erradicados e, junto com o grupo negativo, foram seguidos com endoscopias semestrais e testes de detecção para H. pylori procurando por recidiva ulcerosa e reinfecção no grupo erradicado.RESULTADOS: O grupo positivo foi formado por 25 pacientes, dos quais dois foram considerados não erradicáveis segundo os critérios do protocolo. Os demais foram seguidos por período médio de 38,21 meses e detectadas recidivas em quatro pacientes (17,39%), metade deles (8,69%) foram reinfectados. O grupo negativo foi formado por 26 pacientes, seguido por período médio de 38,28 meses e oito (30,76%) apresentaram recidiva ulcerosa. Não foi evidenciada diferença estatisticamente significativa entre os grupos...

Reparación videolaparoscópica con parche de epiplón en pacientes con úlceras gastroduodenales perforadas: primera experiencia en el Hospital Universitario de Caracas / Laparoscopic repair with omental patch in patients with perforated gastroduodenal ulcers: first experience at the Hospital Universitario de Caracas

El objetivo de este trabajo consistió en aplicar por primera vez en nuestro hospital la técnica laparoscópica de reparación de úlcera gastroduodenal perforada con cierre primario y colocación de parche de epiplón mediante la confección de nudos intracorpóreos a 8 pacientes masculinos, con edades comprendidas entre los 28 y los 74 años, que consultaron a la emergencia del Hospital Universitario de Caracas, con cuadro clínico de abdomen agudo sugestivo de perforación gastroduodenal, en el período comprendido entre noviembre de 2003 y septiembre de 2004. La edad promedio fue 48 años. El tiempo de evolución clínica osciló entre 6 y 48 horas, con un promedio de 11,31 horas. El tiempo operatorio promedio fue 160 minutos. En promedio el dolor posoperatorio fue de 2/10 según EVA (escala visualanalógica para dolor). El promedio de hospitalización fue de 7,85 días. El reintegro a las actividades cotidianas fue en promedio de 13 días. No hubo necesidad de conversión a técnica abierta en ningún caso. Se presentaron complicaciones en 2 pacientes, uno de ellos por reapertura del cierre primario y otro quien presentó colección intrabdominal, ambos fueron reintervenidos de forma abierta, sin complicaciones ulteriores. No hubo mortalidad. La reparación videolaparoscópica constituye un método seguro y efectivo, con excelente resultado estético y menor dolor posoperatorio, por lo que se recomienda ampliamente para el tratamiento de emergencia de los cuadros de úlcera gastroduodenal perforada.

The objective of this work consist to apply for first time in our hospital the laparoscopic repair technique for perforated gastroduodenal ulcers with primary closure and ommental patch using intracorporeal knots. Eight male patients were consults to emergency room of Hospital Universitario de Caracas with ages between 28 and 74 years old, presents clinical syndrome of acute abdomen suggest of perforated gastroduodenal ulcer within period of 2003 November to 2004 September. The mean age was 48 years old. The clinical evolution time before surgery was oscillate between 6 and 48 hours with mean of 11.31 hours. Mean surgery time was 160 minutes. Postoperative pain was 2/10 according to VAS (visual-analog scale for pain). Mean hospitalization days was 7.85 days. Reintegration to daily activities was in mean 13 days. There was not need to conversion to open technique in any case. There were complications in two patients, one of them with reopened of repair site and the other with intrabdominal collection, both were operated in open way without posterior complications. No mortality was occurs. Laparoscopic repair method is secure and effective with excellent cosmetic results and less postoperative pain so we recommended for emergency treatment of perforated gastroduodenal ulcer.

Avaliação tardia de doentes gastrectomizados por úlcera péptica: aspectos clínicos, endoscópicos e histopatológicos / Late follow-up of gastrectomized patients for peptic ulcer: clinical, endoscopic and histopathological aspects

RACIONAL: Atualmente são raras as vezes em que é necessária a realização de uma gastrectomia, já que os inibidores da bomba de prótons associados aos esquemas antibióticos usados para erradicar o Helicobacter pylori, mudaram o enfoque do tratamento da úlcera péptica. OBJETIVOS: Avaliar tardiamente os doentes submetidos a gastrectomia parcial no tratamento da úlcera péptica, em época em que o Helicobacter pylori ainda não era erradicado de forma intencional, incluindo os sintomas pós-operatórios em comparação com os pré-operatórios e a incidência de síndromes pós-gastrectomias; avaliação endoscópica, incluindo o tipo de cirurgia realizada e os achados macroscópicos da mucosa do coto gástrico, duodeno ou jejuno, dependendo do tipo de reconstrução; avaliação histopatológica, incluindo a pesquisa da bactéria por dois métodos: histológico e teste de urease; e sua possível associação presente no estômago remanescente com as avaliações clínica, endoscópica e histopatológica pós-operatórias. CASUíSTICAS E MÉTODOS: Cinqüenta e nove doentes gastrectomizados por úlcera péptica entre os anos de 1985 e 1993 foram avaliados, sendo que 44 (74,6 por cento) eram do sexo masculino e tinham idade média de 55 anos, com variação de 31 a 77 anos, passaram por entrevista clínica e por exame endoscópico. O Helicobacter pylori foi pesquisado nas peças cirúrgicas ressecadas, para constatação da sua presença ou não no pré-operatório. RESULTADOS: A avaliação clínica no pós-operatório tardio mostrou que 96 por cento dos doentes apresentaram excelentes e bons resultados (Visick I e II). Os sintomas pós-operatórios mais comuns foram dispepsia leve e outras queixas, como diarréia, anemia e dumping, que ocorreram, respectivamente, em 11 (18,6 por cento), 2 (3,4 por cento) e 2 (3,4 por cento) casos. A reconstrução tipo Billroth I trouxe melhores resultados clínicos tardios, quando comparada com as reconstruções tipo Billroth II e Y-de-Roux. Na avaliação endoscópica, a maioria dos doentes (52,5 por cento) apresentou exame normal, enquanto que os demais apresentaram gastrites enantematosa (37,3 por cento) e erosiva (8,5 por cento). Recidiva ulcerosa ocorreu em dois doentes (3,4 por cento). Na análise histopatológica, foi observada incidência elevada de gastrite crônica (98,3 por cento). A presença de Helicobacter pylori ocorreu em 86 por cento dos doentes antes da cirurgia e em 89,8 por cento no pós-operatório tardio...

Síndrome do antro gástrico retido: relato de caso / Retained gastric antrum sydrome: a case report

Relata-se o caso de paciente de 63 anos de idade com quadro de úlcera péptica recorrente, secundária à síndrome do antro retido. A causa principal de recorrência ulcerosa é a hipersecreção cloridropéptica secundária à estimulação vagal persistente ou à hipergastrinemia, como ocorre nessa síndrome. O diagnóstico diferencial da hipergastrinemia é algumas vezes difícil, mas importante para a conduta terapêutica. Os diagnósticos clínico, laboratorial e imaginológico pré-operatórios foram de gastrinoma, o que motivou a indicação cirúrgica e a totalização da gastrectomia. O diagnóstico do antro retido foi feito no peroperatório, no momento da reconstrução do trânsito digestivo.

This is report of a 63-years-old patient with recurrent peptic ulcer caused by the retained gastric antrum. Based on clinical, laboratorial, and image evaluation and peroperative diagnosis, total gastrectomy was indicated with a diagnosis of gastrinoma.

Ulcera péptica: complicaciones tardías del tratamineto quirúrgico / Peptic ulcer: late complications of surgical treatment

Aún cuando las intervenciones quirúrgicas para el tratamiento de la úlcera péptica se han reducido marcadamente en los últimos 20 años, debido fundamentalmente a los modernos tratamientos médicos, cerca de un 20 por ciento de los operados se quejan de algún disturbio; y entre el 1-2 por ciento de ellos tienen complicaciones tardías graves, como deficienciuas nutricionales, colelitiasis, esofagitis y gastritis de reflujo alcalino, síndrome de dumping, cáncer del muñón gástrico, los cuales se revisan en el presente artículo

Úlcera péptica terebrante na cabeça do pâncreas: conduta cirúrgica no chamado duodeno difícil / Penetrating peptic ulcer into the head of pancreas: surgical conduct for the difficult duodenum

É apresentada uma conduta cirúrgica para o descolamento do duodeno nas ressecções gastroduodenais por úlcera terebrante na cabeça do pâncreas. Constituem os fundamentos dessa tática a mobilização retrógrada adequada da segunda porção do duodeno por meio da manobra de Kocher, a secção oblíqua do duodeno na altura da borda distal do nicho ulceroso e a introdução, pelo cirurgião, do seu dedo indicador na luz da víscera para palpar a papila duodenal maior. Essa medida permite encontrar o plano de clivagem para separar a parede duodenal da cabeça do pâncreas e afastar o risco de lesão das vias biliares e pancreáticas. O duodeno, assim preparado, possibilita sua utilização para eventual anastomose gastroduodenal ou sua exclusão quando se deseja proceder a gastrojejunostomia

Prevalencia de la infeccion por Helicobacter pylori en el estomago operado por ulcera duodenal y su evolucion clinica, endoscopica e histologica luego de la erradicacion / Prevalence of H. pylori in patients of peptic ulcer disease after erradication

Existe una relación directa entre la enfermedad ulcerosa péptica y la infección por Helicobacter pylori (H. pylori). El objetivo de este estudio fue el de evaluar la prevalencia de H. pylori en pacientes sometidos a gastrectomía o vagotomía con piloroplastia secundaria a úlcera péptica, y su evolución después de la erradicación de la bacteria. Nuestro grupo de estudio encontró una baja prevalencia de infección por H. pylori en pacientes con gastrectomía o vagotomía con piloroplastia. Probablemente, el constante reflujo biliar en este tipo de cirugía produce cambios que inhiben la colonización de la bacteria

Consideraçöes sobre o tratamento cirúrgico da úlcera péptica gastroduodenal: análise de 65 casos / Surgical treatment of gastroduodenal peptic ulcer: analysis of 65 cases

Relata-se a experiência no tratamento cirúrgico de 65 casos de pacientes portadores de úlcera péptica gastro-duodenal, destacando-se a necessidade do cirurgiäo em adaptar a técnica operatória às reais necessidades de cada caso em particular, o que contribuirá para uma reduçäo da taxa de recorrência da úlcera péptica e minimizará as seqüelas do tratamento cirúrgico