Detalhe da pesquisa
1.
A novel tricyclic ß-lactam exhibiting potent antibacterial activities against carbapenem-resistant Enterobacterales: Synthesis and structure-activity-relationships.
Bioorg Med Chem
; 46: 116343, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450571
2.
Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection.
PLoS One
; 16(5): e0249841, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33939697
3.
Structure-chiroptical properties relationship of carbapenams by experiment and theory.
J Org Chem
; 75(21): 7219-26, 2010 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20873777
4.
Ferrier-Petasis rearrangement of 4-(vinyloxy)azetidin-2-ones: an entry to carbapenams and carbacephams.
J Org Chem
; 75(20): 6990-3, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20853897
5.
Synthesis of novel di- and tricationic carbapenems with potent anti-MRSA activity.
Bioorg Med Chem Lett
; 19(2): 447-50, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19056265
6.
Novel lbeta-methylcarbapenems having cyclic sulfonamide moieties: synthesis and evaluation of in-vitro biological activity - part II.
Arch Pharm (Weinheim)
; 342(9): 528-32, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19598286
7.
Successive copper(I)-catalyzed cross-couplings in one pot: a novel and efficient starting point for synthesis of carbapenems.
Org Lett
; 10(13): 2737-40, 2008 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-18510330
8.
Diastereoselective synthesis of carbapenams via Kinugasa reaction.
J Org Chem
; 73(18): 7402-4, 2008 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18686999
9.
Synthesis and in-vitro activity of new 1beta-methylcarbapenem derivatives as antibacterial agents.
Arch Pharm (Weinheim)
; 341(12): 780-6, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19009543
10.
Novel lbeta-methylcarbapenems having cyclic sulfonamide moieties: synthesis and evaluation of in vitro antibacterial activity.
Eur J Med Chem
; 42(9): 1176-83, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17418453
11.
Synthesis and antibacterial evaluation of 1beta-methyl-2-[5-(1-methoxyimino-2-substituted sulfonamide ethyl)pyrrolidin-3-ylthio]carbapenems and their related compounds.
Eur J Med Chem
; 42(3): 358-64, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17156896
12.
Formal synthesis of Thienamycin.
J Antibiot (Tokyo)
; 70(6): 781-787, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28377636
13.
Synthesis and biological evaluation of 1beta-methylcarbapenems having cyclic thiourea moieties and their related compounds.
Eur J Med Chem
; 41(7): 825-32, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16737759
14.
Synthesis and biological evaluation of 1beta-methylcarbapenems having guanidino moieties.
Eur J Med Chem
; 41(1): 50-5, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16260069
15.
Synthesis and in vitro activity of a series 1beta-methylcarbapenem derivatives.
Eur J Med Chem
; 41(10): 1201-9, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16797791
16.
Synthesis and antibacterial activities of new 1beta-methylcarbapenems having aminopyrimidinylthioether moiety.
Eur J Med Chem
; 41(11): 1347-51, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16973246
17.
Syntheses and pharmacokinetic studies of prodrug esters for the development of oral carbapenem, L-084.
J Antibiot (Tokyo)
; 59(4): 241-7, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16830892
18.
Simultaneous hydrogenolysis of p-nitrobenzyl esters and carbamates side-chains in the THF 1beta-carbapenem OCA-983 in biphasic media.
Med Chem
; 2(1): 21-5, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16787352
19.
1,3-Dipolar cycloaddition of a cyclic nitrone derived from 2-deoxy-D-ribose to α,ß-unsaturated lactones: An entry to carbapenem antibiotics.
Carbohydr Res
; 433: 89-96, 2016 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27471832
20.
Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of L,D-Transpeptidase LdtMt1 of Mycobacterium tuberculosis and the Stability toward Hydrolysis by ß-Lactamase BlaC.
J Med Chem
; 59(7): 3427-38, 2016 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26937999