Bilateral coronoid hyperplasia: a report of six cases.

Bilateral coronoid process hyperplasia is a rare condition defined as an abnormal elongation of the mandibular coronoid process, formed of histologically normal bone. Coronoid process hyperplasia usually develops progressively, and the clinical symptoms are often similar to those of temporomandibular joint disorders (TMD). Therefore, it is often misdiagnosed as TMD initially. From 2013 to 2016, six patients were referred to our maxillofacial surgery unit by their dentist, to evaluate mouth opening with suspected TMJ disorder. Average age was 30 years No hypertrophy of the masseter muscles was found and the patient had no history of pain and/or dysfunction of the temporomandibular joint. Average maximal incisal opening was 16.3 mm. (Rance 13-20 mm). At the end of surgery the average mouth opening achieved was of 40.3 mm. After 6 months from surgery an average mouth opening of 41 mm was obtained, with no recidivism in the coronoid process growth or decrease in the mouth opening. The only successful treatment to restore the mouth opening caused by coronoid process hyperplasia is surgical correction of coronoid-malar interference by coronoidectomy or coronoidotomy. Commencement of physiotherapy is recommended to begin between three days and one week after surgery. We also recommend the use of the TeraBite®, a simple manual physiotherapy device.

Dosed myofascial release in three-dimensional bioengineered tendons: effects on human fibroblast hyperplasia, hypertrophy, and cytokine secretion.

OBJECTIVE: The purpose of this study was to investigate potential differences of magnitudes and durations associated with dosed myofascial release (MFR) on human fibroblast proliferation, hypertrophy, and cytokine secretions. METHODS: Bioengineered tendons (BETs) attached to nylon mesh anchors were strained uniaxially using a vacuum pressure designed to model MFR varying in magnitudes (0%, 3%, 6%, 9%, and 12% elongation) and durations (0.5 and 1-5 minutes). Conditioned media were analyzed for cytokine secretion via protein microarray (n = 2). Bioengineered tendons were weighted and fibroblasts extracted from the BET were assessed for total cell protein and proliferation via double-stranded DNA quantification (n = 5). All data were compared by a 1-way analysis of variance with post hoc Dunnett test and Student t test. RESULTS: Changing MFR magnitude and duration did not have an effect on total fibroblast cellular protein or DNA accumulation. However, we observed a stepwise increase in BET weight with higher-magnitude MFR treatments. Longer durations of MFR resulted in progressive increase in the secretions of angiogenin, interleukin (IL)-3, IL-8, growth colony-stimulating factor, and thymus activation-regulated chemokine. Alternatively, increasing strain magnitude induced secretions of IL-1ß, monocyte chemoattractant cytokine, and regulated and normal T cell expressed and secreted chemotactic cytokine. CONCLUSION: Cellular proliferation and hypertrophy were not significantly changed by any treatment. However, the change in total BET dry weight suggests that production of extracellular matrix protein may be up-regulated. Different MFR parameters induce secretions of a unique subset of cytokines and growth factors that can be further enhanced by increasing the magnitude and duration of treatment. If clinically translatable, these results suggest that variations to manual therapy biomechanical parameters may differentially affect physiological responses in vivo.

Masson's tumor of the pineal region: case report.

Intracranial intravascular papillary endothelial hyperplasia (IPEH), also referred to as Masson's tumor, is a condition that rarely occurs in the nervous system. IPEH most frequently occurs extracranially in the skin of the face, skull, neck, and trunk and can easily be mistaken clinically, radiologically, and histologically for angiosarcoma, organizing hematoma, or other vascular malformations. IPEH accounts for roughly 2% of all vascular tumors and is extremely rare intracranially, with only 23 reported cases compared with more than 300 cases of IPEH occurring in the skin and subcutaneous tissue. To date, it has never been reported to occur in the pineal region. The authors report the case of a patient with an IPEH in the pineal region who underwent complex resection and experienced reversal of neurological symptoms.

[The sanatorium-health resort treatment of children with thyroid hyperplasia]. / Sanatorno-kurortnoe lechenie detei s giperplaziei shchitovidnoi zhelezy.

A favourable effect of sanatorium treatment on the key body functions was found in children with thyroid hyperplasia consequent to environmental pollution due to Chernobyl accident. It is emphasized that balneofactors in the above children should be used in sparing regimens.

[A spectral analysis of the cardiac rhythm in children with cardiovascular diseases living in areas under radiation control]. / Spektral'nyi analiz serdechnogo ritma u detei s serdechno-sosudistymi zabolevaniiami, prozhivaiushchikh na territoriiakh radiatsionnogo kontrolia.

Spectral analysis of cardiac rhythm has determined characteristics of humoral, sympathetic and parasympathetic regulation in children with cardiac abnormalities and thyroid hyperplasia. The examinees demonstrated low activity of humoral immunity, high sympathetic influences, slight variability of frequency-amplitude characteristics. Sanatorium treatment improved regulation of cardiac activity. Spectral analysis of cardiac rhythm proved efficient for optimization of physiotherapy.

Abordaje surgery first en disgnacia clase III con hiperplasia condilar activa / Surgery First approach in skeletal class iii with condylar hyperplasia

Las anomalías dentofaciales funcionales o disgnacias esqueléticas afectan a la población colombiana por encima de un 70%, y son causa de alteraciones sistémicas nutricionales por la maloclusión y la deglución atípica presente, así como en el desarrollo y funcionamiento orgánico por la disnea o inclusive apnea del sueño concomitante, y no menos importante, el impacto psicosocial, que se deriva en baja autoestima, depresión, síndrome maniaco-depresivo y/o suicidio. La cirugía ortognática, como única opción real y definitiva para tal morbilidad, sigue siendo declinada por los planes obligatorios de salud territoriales, debido a su errónea categorización de procedimiento estético, que inherentemente obliga a los pacientes a acceder a ellos de manera particular. A continuación se presenta el tratamiento inmediato de una disgnacia clase III con hiperplasia condilar activa, mediante abordaje “surgery first”, manejado por el Servicio de Otorrinolaringología y Cirugía Maxilofacial del Hospital de San José (Bogotá - Colombia)...

Dentofacial functional or disgnacias skeletal abnormalities affect the Colombian population above 70%, causing systemic nutritional alterations by the malocclusion and atypical swallowing present, alterations in development and organic performance by dyspnea, or even sleep apnea concomitantly, and not least, the psychosocial impact resulting in low self-esteem, depression, manic-depressive syndrome and/ or suicide. Orthognathic surgery as the only real and definitive option for such morbidity is being declined by mandatory territorial health plans because of its erroneous categorization of cosmetic procedure that inherently requires patients to access them in particular. Below an immediate treatment of a disgnacia class III with condylar hyperplasia active approach “Surgery First” managed by the Service of Otolaryngology and Maxilofacial Surgery of the San José Hospital (Bogotá - Colombia)...