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1.
Rheumatol Int ; 39(9): 1499-1505, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30888472

RESUMO

This article aims to and describes the characteristics of rheumatology practice in Japan, focusing on the medical environment for the treatment of rheumatoid arthritis (RA). In Japan, the introduction of biological disease-modifying anti-rheumatic drugs (bDMARDs) has led to a significant paradigm shift in medical care; satisfactory safety outcomes have been demonstrated by periodic analysis, post-market surveillance and the development of guidelines via an industry-academia-government collaboration. Drug discontinuation is also considered an option, as well as medical economic analysis of any increase in the financial burden engendered by use of bDMARDs. Tocilizumab, a bDMARD established in Japan, was developed in an environment that facilitates translational research. The rheumatology community in Japan is expected to continue to develop novel therapies, while ensuring consistent quality of medical care despite limited healthcare resources.


Assuntos
Antirreumáticos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Produtos Biológicos/uso terapêutico , Padrões de Prática Médica/tendências , Reumatologistas/tendências , Reumatologia/tendências , Antirreumáticos/efeitos adversos , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/epidemiologia , Artrite Reumatoide/imunologia , Produtos Biológicos/efeitos adversos , Difusão de Inovações , Descoberta de Drogas/tendências , Substituição de Medicamentos/tendências , Uso de Medicamentos/tendências , Previsões , Humanos , Japão/epidemiologia , Resultado do Tratamento
2.
Clin Exp Rheumatol ; 36(6): 1014-1021, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29846160

RESUMO

OBJECTIVES: Management of rheumatic diseases (RD) is often problematic in pregnant patients, hence the need for guideline implementation. This survey-based study aimed to assess beliefs among obstetricians and rheumatologists about managing RD in pregnant Lebanese patients. METHODS: Questionnaires were completed by a representative sample of rheumatologists and obstetricians practicing throughout Lebanon. Collected data included physicians' information, opinion on pregnancy in RD patients, compatible drugs with fertility, pregnancy and breastfeeding, references used in their clinical management, referral to specialists, and knowledge about guidelines. Qualitative variables were analysed using Chi-square or Fisher's exact tests, and quantitative variables using Wilcoxon or Student t-tests. Results were matched against a scoring system based on the EULAR/BSR guidelines. p-value <0.05 indicated statistical significance. RESULTS: Analysis showed high response rates of physicians, especially among rheumatologists. Overall, physicians practice was in concordance with international guidelines and only few misconceptions were reported. Systemic lupus erythematosus (SLE) was associated with risk on fertility, foetal malformation and eclampsia while anti-phospholipid (APL) syndrome was associated with miscarriage and vasculitis with eclampsia. Spondyloarthritis was considered 'safe' in pregnancy. Most physicians think that cyclophosphamide, leflunomide, methotrexate, mycophenolate mofetil and azathioprine compromise fertility, pregnancy, and breastfeeding. CONCLUSIONS: Our data showed relatively good concordance of the physicians' beliefs with the current literature and recommendations. However, we identified misconceptions about anti-rheumatic drugs safety in pregnancy and discrepancy between rheumatologists and obstetricians practices; hence the need for promoting collaboration between both specialties and disseminating knowledge to physicians and patients in the Middle East region.


Assuntos
Antirreumáticos/uso terapêutico , Obstetrícia/tendências , Padrões de Prática Médica/tendências , Complicações na Gravidez/tratamento farmacológico , Doenças Reumáticas/tratamento farmacológico , Reumatologistas/tendências , Reumatologia/tendências , Antirreumáticos/efeitos adversos , Feminino , Fidelidade a Diretrizes , Pesquisas sobre Atenção à Saúde , Humanos , Líbano , Obstetrícia/normas , Guias de Prática Clínica como Assunto , Padrões de Prática Médica/normas , Gravidez , Complicações na Gravidez/diagnóstico , Complicações na Gravidez/imunologia , Doenças Reumáticas/diagnóstico , Doenças Reumáticas/imunologia , Reumatologistas/normas , Reumatologia/normas , Medição de Risco , Fatores de Risco
3.
Rheumatol Int ; 38(11): 2111-2120, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-30306254

RESUMO

This study aimed at providing a current and nearly complete picture of the patterns of the initiation of disease-modifying antirheumatic drugs (DMARDs) in patients with newly diagnosed RA. Based on ambulatory drug prescription data and physician billing claims data covering 87% of the German population, we assembled a cohort of incident RA patients aged 15-79 years (n = 54,896) and assessed the prescription frequency of total DMARDs, conventional synthetic (csDMARDs) and biologic DMARDs (bDMARDs) within the first year of disease. Using multiple logistic regression, we estimated the chance of early DMARD receipt based on age, sex, serotype and specialty of prescribing physician while controlling for region of residence. In total, 44% of incident RA patients received a DMARD prescription within the first year of disease. In multiple regression, younger patients (< 35 years) had 1.7-fold higher chances of receiving a csDMARD than patients aged ≥ 65 years [odds ratio (OR): 1.65 with 95% confidence interval (CI) 1.51-1.80] and almost tenfold higher chances to receive a bDMARD [OR (95% CI) 9.5 (8.0-11.3)]. Seropositivity and a visit to a rheumatologist were positively associated with DMARD initiation [OR (95% CI) 2.8 (2.6-2.9) and 5.9 (5.6-6.2) for csDMARDs, respectively]. Based on data covering 87% of the German population, the present study revealed that less than half of incident RA patients receive DMARDs within the first year of disease and that marked differences exist according to age. The study highlights the importance of involving a rheumatologist early in the management of RA.


Assuntos
Assistência Ambulatorial/tendências , Antirreumáticos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Padrões de Prática Médica/tendências , Reumatologistas/tendências , Adolescente , Adulto , Fatores Etários , Idoso , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/epidemiologia , Tomada de Decisão Clínica , Prescrições de Medicamentos , Feminino , Alemanha/epidemiologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Encaminhamento e Consulta/tendências , Estudos Retrospectivos , Fatores de Tempo , Adulto Jovem
4.
Rheumatol Int ; 38(4): 589-598, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29368023

RESUMO

To describe variability in the prescription of biologics (B-DMARDs) for patients with rheumatoid arthritis (RA) in hospitals in Spain, and to explore which characteristics of the patient, the doctor and the hospital are associated with this variability. Cross-sectional multicentric study in 46 rheumatology services of the National Health System. Medical records of 1188 randomly selected patients were reviewed. The association of each variable with B-DMARD prescription was analyzed using simple logistic regressions. Multilevel logistic regression models were created to analyze variability among centers. 36.8% of patients had received B-DMARD. The proportion of patients being treated with B-DMARDs varied between 3.6 and 71.4% depending on the center. Association of prescription of B-DMARD with patient age (OR = 0.958, 95% CI = 0.947-0.968, p < 0.001), longer disease duration (OR = 1.05, 95% CI = 1.032-1.069, p < 0.001), higher CRP levels (OR = 1.022, 95% CI = 1.003-1.042, p = 0.023), and higher number of hospitalizations (OR = 1.286, 95% CI = 1.145-1.446, p < 0.001) was observed. With regard to the center characteristics, the existence of telephone consultations (OR = 1.438, 95% CI = 1.037-1.994, p = 0.03) and the number of beds (OR = 1.045, 95% CI = 1.001-1.091, p = 0.044) were positively associated with prescription of B-DMARDs. Patient variables explained 34.04% of the variability among centers. By adjusting for patient and hospital characteristics, it went up to 83.71%. There is variability in the prescription of B-DMARDs for patients with RA among hospitals which is associated, to a greater extent, with the center characteristics. B-DMARDs prescription could be partly explained by other factors not covered by the current study including the provider's attitudes towards biologics and other hospital characteristics.


Assuntos
Artrite Reumatoide/tratamento farmacológico , Produtos Biológicos/uso terapêutico , Padrões de Prática Médica/tendências , Reumatologistas/tendências , Idoso , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/epidemiologia , Estudos Transversais , Prescrições de Medicamentos , Feminino , Número de Leitos em Hospital , Hospitalização/tendências , Hospitais Públicos/tendências , Humanos , Modelos Logísticos , Masculino , Prontuários Médicos , Pessoa de Meia-Idade , Análise Multivariada , Razão de Chances , Consulta Remota/tendências , Espanha/epidemiologia , Fatores de Tempo
5.
Rheumatol Int ; 38(4): 649-656, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29302803

RESUMO

The objectives of this study are to identify the prevalence and incidence of rheumatoid arthritis (RA) and to investigate the patterns of medical care and drug utilization by RA patients in Korea. Korean National Health Insurance claims data were used for analysis. RA patients were defined as those having an RA code from 2009 to 2012 and using disease-modifying anti-rheumatic drugs (DMARDs) within 1 year after the code. RA patients identified in 2010 with a disease-free period for 12 months before the index date, and those who received continuous treatment in 2011-2013 were defined as incident cases. Patterns of medical care and drug utilization were compared among subgroups. The prevalence of RA increased yearly from 0.28% in 2009 to 0.32% in 2012. The incidence of RA in 2010 was 28.5 per 100,000 person-years. The use of biologic DMARDs (bDMARDs) increased from 2.31% in 2009 to 4.05% in 2012. Hydroxychloroquine (57.53-62.45%) was the most commonly used the conventional DMARDs, followed by methotrexate (49.99-51.87%). The use of bDMARDs (1.39 vs. 2.43%) was less frequent in EORA patients than YORA patients. Hydroxychloroquine (74.96 vs. 72.11%) was more frequently used, but methotrexate (55.24 vs. 59.25%) and sulfasalazine (27.96 vs. 32.72%) were used less frequently in EORA patients than in YORA patients. The prevalence of RA has increased in Korea. EORA patients used fewer bDMARDs, methotrexate, and sulfasalazine but more hydroxychloroquine than YORA patients.


Assuntos
Antirreumáticos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Artrite Reumatoide/epidemiologia , Produtos Biológicos/uso terapêutico , Padrões de Prática Médica/tendências , Reumatologistas/tendências , Demandas Administrativas em Assistência à Saúde , Adolescente , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Antirreumáticos/efeitos adversos , Artrite Reumatoide/diagnóstico , Produtos Biológicos/efeitos adversos , Bases de Dados Factuais , Revisão de Uso de Medicamentos , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Prevalência , República da Coreia/epidemiologia , Fatores de Tempo , Resultado do Tratamento , Adulto Jovem
6.
Rheumatol Int ; 38(4): 663-668, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29204683

RESUMO

To analyze the biologics usage and expenditure for the treatment of patients with rheumatoid arthritis (RA) in each prefecture throughout Japan using the national open database, the Ministry of Health, Labour and Welfare of Japan disclosed; in Oct 2016, the data of the top 30 most-frequently prescribed drugs during a 1-year period from April 2014 to March 2015 in each prefecture in Japan, along with the patients' age and sex. Seldom-used drugs were excluded. We picked up only biologics for the present study. The total expenditure on biologics used in each prefecture was correlated with the population thereof. However, there was a big difference, up to ~ twofold, in the average expenditure used for an RA patient: highest in Toyama and lowest in Wakayama. There was also a big difference, ~ 4.5-fold, in the number of rheumatologists/1000 RA patients, highest in Kyoto and lowest in Aomori. The average expenditure used for an RA patient was correlated with the number of rheumatologists in the western part of Japan. Etanercept seemed to be used most frequently to Japanese RA patients followed closely by infliximab. Abatacept was used more frequently to the elderly than other biologics. There was a big difference in the number of rheumatologists and expenditure on biologics for the treatment of an RA patient among prefectures in fiscal 2014. Factors that brought this unevenness need to be scrutinized for universal implementation of good RA care throughout Japan, where there are uniform health insurance system and free access to rheumatologists.


Assuntos
Demandas Administrativas em Assistência à Saúde , Antirreumáticos/economia , Antirreumáticos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Artrite Reumatoide/economia , Produtos Biológicos/economia , Produtos Biológicos/uso terapêutico , Bases de Dados Factuais , Custos de Medicamentos/tendências , Gastos em Saúde/tendências , Padrões de Prática Médica , Reumatologistas , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Antirreumáticos/efeitos adversos , Artrite Reumatoide/diagnóstico , Produtos Biológicos/efeitos adversos , Criança , Pré-Escolar , Análise Custo-Benefício , Revisão de Uso de Medicamentos/economia , Revisão de Uso de Medicamentos/tendências , Feminino , Disparidades em Assistência à Saúde/economia , Disparidades em Assistência à Saúde/tendências , Humanos , Lactente , Recém-Nascido , Japão , Masculino , Pessoa de Meia-Idade , Padrões de Prática Médica/economia , Padrões de Prática Médica/tendências , Reumatologistas/economia , Reumatologistas/tendências , Fatores de Tempo , Resultado do Tratamento , Adulto Jovem
7.
Clin Exp Rheumatol ; 35(3): 477-483, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28134086

RESUMO

OBJECTIVES: To explore patterns of real-world early RA (ERA) care across countries. METHODS: An online survey was disseminated to practising rheumatologists across Europe and the US, also made accessible on social media between April and May 2015. Survey questions (n=38) assessed the structure and setting of ERA clinics, times to diagnosis and treatment, patient monitoring, guideline use and data recording. RESULTS: A total of 212 rheumatologists from 39 countries (76% European) completed the survey. 62% had an ERA clinic based at a university hospital. Patient referral to rheumatology was mainly (78%) via primary care; 44% had an agreed ERA local referral pathway, 15% a national pathway. Only 16% had dedicated ERA clinics, the majority being practitioners in Northern Europe with access to a local or national referral pathway. Data for research were collected by 42%. Treatment guidelines were followed by the majority, especially rheumatologists practising in Europe. Variations existed in the use of initial DMARDs with treatment decisions reported to be influenced by international/national guidelines in 71%/61%. No significant relationship between country gross national income and the availability of ERA clinics was seen. CONCLUSIONS: This study provides comparative benchmark information regarding the global provision of ERA care. Substantial variations exist in referral and early assessment pathways with guidelines having a most apparent impact in Northern Europe. Provision of an ERA service does not appear to be constrained by cost, with conceptual factors, e.g. clinician engagement, perhaps playing a role. These initial insights could potentially help harmonise ERA management across countries.


Assuntos
Antirreumáticos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Prestação Integrada de Cuidados de Saúde/tendências , Disparidades em Assistência à Saúde/tendências , Padrões de Prática Médica/tendências , Reumatologistas/tendências , Corticosteroides/uso terapêutico , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/epidemiologia , Produtos Biológicos/uso terapêutico , Procedimentos Clínicos/tendências , Estudos Transversais , Europa (Continente)/epidemiologia , Fidelidade a Diretrizes , Pesquisas sobre Atenção à Saúde , Humanos , Guias de Prática Clínica como Assunto , Encaminhamento e Consulta/tendências , Fatores de Tempo , Resultado do Tratamento , Estados Unidos/epidemiologia
8.
Clin Exp Rheumatol ; 35(3): 379-383, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28339354

RESUMO

OBJECTIVES: To examine the effects of an educational meeting and subsequent computer reminders on the number of ordered laboratory tests. METHODS: Using interrupted time series analysis we assessed whether trends in the number of laboratory tests ordered by rheumatologists between September 2012 and September 2015 at the Sint Maartenskliniek (the Netherlands) changed following an educational meeting (September 2013) and the introduction of computer reminders into the Computerised Physician Order Entry System (July 2014). The analyses were done for the set of tests on which both interventions had focussed (intervention tests; complement, cryoglobulins, immunoglobins, myeloma protein) and a set of control tests unrelated to the interventions (alanine transferase, anti-cyclic citrullinated peptide, C-reactive protein, creatine, haemoglobin, leukocytes, mean corpuscular volume, rheumatoid factor and thrombocytes). RESULTS: At the start of the study, 101 intervention tests and 7660 control tests were ordered per month by the rheumatologists. After the educational meeting, both the level and trend of ordered intervention and control tests did not change significantly. After implementation of the reminders, the level of ordered intervention tests decreased by 85.0 tests (95%-CI -133.3 to -36.8, p<0.01), the level of control tests did not change following the introduction of reminders. CONCLUSIONS: In summary, an educational meeting alone was not effective in decreasing the number of ordered intervention tests, but the combination with computer reminders did result in a large decrease of those tests. Therefore, we recommend using computer reminders in addition to education if reduction of inappropriate test use is aimed for.


Assuntos
Análise Química do Sangue/estatística & dados numéricos , Técnicas de Laboratório Clínico/estatística & dados numéricos , Testes Diagnósticos de Rotina/estatística & dados numéricos , Educação Médica Continuada/métodos , Capacitação em Serviço/métodos , Sistemas de Registro de Ordens Médicas/estatística & dados numéricos , Padrões de Prática Médica , Sistemas de Alerta/estatística & dados numéricos , Reumatologistas/educação , Biomarcadores/sangue , Análise Química do Sangue/tendências , Técnicas de Laboratório Clínico/tendências , Testes Diagnósticos de Rotina/tendências , Humanos , Análise de Séries Temporais Interrompida , Sistemas de Registro de Ordens Médicas/tendências , Países Baixos , Padrões de Prática Médica/tendências , Valor Preditivo dos Testes , Sistemas de Alerta/tendências , Reumatologistas/tendências , Fatores de Tempo , Procedimentos Desnecessários
9.
Rheumatol Int ; 37(9): 1453-1459, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28551723

RESUMO

The objective of this study is to describe the composition of multidisciplinary teams (MDT) working within rheumatology departments across the UK. All rheumatology departments in the United Kingdom (UK) were invited to participate in a national electronic survey between February 2014 and April 2015 as a part of a national audit for the management of rheumatoid and early inflammatory arthritis commissioned by Healthcare Quality Improvement Partnership. Rheumatology departments were asked to report their MDT composition; defined as a rheumatologist (consultant or specialist trainee), specialist nurse, occupational therapist physiotherapist, and podiatrist. The data were collected as Whole Time Equivalent (WTE) of each professional group at each department adjusted to 100,000 population. The data were grouped according to British Society for Rheumatology regions to study regional variations. The survey was completed by 164/167 departments (98% response rate). All departments reported an MDT comprising a rheumatologist (consultant or specialist trainee) and almost all included a specialist nurse but only 28 (17%) of the departments had MDTs comprising all the professional groups. There was a high degree of regional variation in the provision of Allied Health Professionals (physiotherapists, occupational therapists, and podiatrists) in the UK. MDT care is recommended for the management of inflammatory arthritis, but few UK rheumatology departments have a full complement of healthcare professionals within their MDT. There is a high degree of regional variation in the composition and staffing levels of the rheumatology MDT across the UK; the impact of which warrants further investigation.


Assuntos
Departamentos Hospitalares/tendências , Equipe de Assistência ao Paciente/tendências , Doenças Reumáticas/terapia , Reumatologia/estatística & dados numéricos , Estudos Transversais , Prestação Integrada de Cuidados de Saúde/tendências , Pesquisas sobre Atenção à Saúde , Disparidades em Assistência à Saúde/tendências , Humanos , Comunicação Interdisciplinar , Auditoria Médica , Enfermeiros Especialistas/tendências , Terapeutas Ocupacionais/tendências , Fisioterapeutas/tendências , Podiatria/tendências , Doenças Reumáticas/diagnóstico , Doenças Reumáticas/fisiopatologia , Reumatologistas/educação , Reumatologistas/tendências , Reino Unido , Recursos Humanos
10.
Clin Exp Rheumatol ; 34(5): 880-884, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27243269

RESUMO

OBJECTIVES: The evidence base for treatment of the idiopathic inflammatory myopathies is extremely limited. The rarity and heterogeneity of these diseases has hampered the development of good quality clinical trials and while a range of immunomodulatory treatments are commonly used in clinical practice, as yet there are no clear guidelines directing their use. We aimed to establish current prescribing regimens used to treat adults with myositis internationally. METHODS: An electronic survey based on different clinical scenarios was distributed internationally to clinicians involved in the treatment of patients with myositis. Participants were asked to select their first-line treatment preferences in each situation. A multinomial regression analysis was used to assess the influence of clinical scenario, respondent expertise and country of origin on first-line treatment choice. RESULTS: 107 survey responses were received. 57% of respondents considered themselves an expert in myositis and the majority of respondents were rheumatologists although responses from other specialities were also received. Pharmacological treatment with steroids and additional immunotherapy was the preference in most scenarios. First-line immunosuppressant choice was significantly influenced by the clinical scenario, the expertise of the treating physician and country of practice. Azathioprine, methotrexate and mycophenolate mofetil were the most commonly chosen agents. CONCLUSIONS: In the absence of available evidence, clinical experience and expert consensus often forms the basis of treatment guidelines. These results suggest that an international consensus approach would be possible in myositis and would overcome an urgent, yet unmet need for patients suffering with this difficult disease.


Assuntos
Imunossupressores/uso terapêutico , Miosite/tratamento farmacológico , Padrões de Prática Médica/tendências , Reumatologistas/tendências , Reumatologia/tendências , Atitude do Pessoal de Saúde , Consenso , Prescrições de Medicamentos , Pesquisas sobre Atenção à Saúde , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Imunossupressores/efeitos adversos , Miosite/diagnóstico , Fenótipo , Padrões de Prática Médica/normas , Reumatologistas/psicologia , Reumatologistas/normas , Reumatologia/normas
12.
Arthritis Care Res (Hoboken) ; 73(5): 680-686, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-31961491

RESUMO

OBJECTIVE: Information about the prediagnosis period in psoriatic arthritis (PsA) is limited. The present study was undertaken to compare health care utilization related to musculoskeletal issues during a 5-year period prior to the diagnosis of PsA versus that of subjects with no prior inflammatory arthritis within a primary care setting. METHODS: We conducted a population-based, matched cohort study using electronic medical records and administrative data in Ontario, Canada. Age- and sex-matched cohorts of PsA patients and comparators from the same family physicians were assembled. Comparators were not allowed to have prior spondyloarthritis, ankylosing spondylitis, or rheumatoid arthritis billing code diagnoses. The study outcomes included health care utilization and costs related to nonspecific musculoskeletal issues during a 5-year period prior to the index date. RESULTS: We studied 462 PsA patients and 2,310 matched comparators. The odds ratio (OR) related to visiting a primary care physician for nonspecific musculoskeletal issues in patients with PsA was 2.14 (95% confidence interval 1.73-2.64) in the year immediately preceding the index date and was similarly elevated up to 5 years prior. The OR related to using other musculoskeletal-related health care services, including musculoskeletal specialists visits, joint injections, joint imaging, and emergency department visits, was higher in PsA as early as 5 years preceding the index date. Total and musculoskeletal-related health care costs prior to the index date were higher for patients with PsA versus comparators. CONCLUSION: A prodromal PsA phase characterized by nonspecific musculoskeletal symptoms may exist. Further study is needed to determine if this represents a window for earlier diagnosis of PsA.


Assuntos
Artrite Psoriásica/terapia , Recursos em Saúde/tendências , Atenção Primária à Saúde/tendências , Reumatologia/tendências , Adulto , Idoso , Artrite Psoriásica/diagnóstico , Estudos de Casos e Controles , Bases de Dados Factuais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Visita a Consultório Médico/tendências , Ontário , Encaminhamento e Consulta/tendências , Reumatologistas/tendências , Fatores de Tempo
13.
Arthritis Care Res (Hoboken) ; 73(7): 998-1003, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-33058485

RESUMO

OBJECTIVE: To assess the experience, views, and opinions of rheumatology providers at Veterans Affairs (VA) facilities about rheumatic disease health care issues during the COVID-19 pandemic. METHODS: We performed an anonymized cross-sectional survey, conducted from April 16 to May 18, 2020, of VA rheumatology providers. We assessed provider perspectives on COVID-19 issues and resilience. RESULTS: Of the 153 eligible VA rheumatologists, 103 (67%) completed the survey. A significant proportion of providers reported a ≥50% increase related to COVID-19 in visits by telephone (53%), video-based VA video connect (VVC; 44%), and clinical video telehealth with a facilitator (29%). A majority of the responders were somewhat or very comfortable with technology for providing health care to established patients during the COVID-19 pandemic using telephone (87%), VVC (64%), and in-person visits (54%). A smaller proportion were comfortable with technology providing health care to new patients. At least 65% of rheumatologists considered telephone visits appropriate for established patients with gout, osteoporosis, polymyalgia rheumatica, stable rheumatoid arthritis, stable spondyloarthritis, or osteoarthritis; 32% reported a rheumatology medication shortage. Adjusted for age, sex, and ethnicity, high provider resilience was associated with significantly higher odds ratios (ORs) of comfort with technology for telephone (OR 3.1 [95% confidence interval (95% CI) 1.1-9.7]) and VVC visits for new patients (OR 4.7 [95% CI 1.4-15.7]). CONCLUSION: A better understanding of COVID-19 rheumatic disease health care issues using a health-system approach can better inform providers, improve provider satisfaction, and have positive effects on the care of veterans with rheumatic disease.


Assuntos
COVID-19 , Padrões de Prática Médica/tendências , Doenças Reumáticas/terapia , Reumatologistas/tendências , Reumatologia/tendências , Telemedicina/tendências , United States Department of Veterans Affairs/tendências , Atitude do Pessoal de Saúde , Atitude Frente aos Computadores , Estudos Transversais , Feminino , Pesquisas sobre Atenção à Saúde , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Reumáticas/diagnóstico , Fatores de Tempo , Estados Unidos
14.
Int J Rheum Dis ; 24(10): 1235-1246, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34323382

RESUMO

Conditions prompting physicians and surgeons first adapting endoscopes to peer into joints were mainly the sort of synovial conditions that would concern today's rheumatologists. Rheumatologists were among the pre-World War II pioneers developing and documenting arthroscopy. The post-War father of modern arthroscopy, Watanabe, found rheumatologists among his early students, who took back the technique to their home countries, teaching orthopedists and rheumatologists alike. Rheumatologists described and analyzed the intra-articular features of their common diseases in the '60s and '70s. A groundswell of interest from academic rheumatologists in adapting arthroscopy grew considerably in the '90s with development of "needle scopes" that could be used in an office setting. Rheumatologists helped conduct the very trials the findings of which reduced demand for their arthroscopic services by questioning the efficacy of arthroscopic debridement in osteoarthritis (OA) and also developing biological compounds that greatly reduced the call for any resective intervention in inflammatory arthropathies. The arthroscope has proven an excellent tool for viewing and sampling synovium and continues to serve this purpose at several international research centers. While cartilage is now imaged mainly by magnetic resonance imaging, some OA features - such as a high prevalence of visible calcinosis - beg further arthroscopy-directed investigation. A new generation of "needle scopes" with far superior optics awaits future investigators, should they develop interest.


Assuntos
Artroscópios , Artroscopia/instrumentação , Artropatias/cirurgia , Padrões de Prática Médica , Reumatologistas , Artroscópios/história , Artroscópios/tendências , Artroscopia/história , Artroscopia/tendências , Difusão de Inovações , Previsões , História do Século XX , História do Século XXI , Humanos , Artropatias/diagnóstico por imagem , Artropatias/história , Artropatias/patologia , Padrões de Prática Médica/história , Padrões de Prática Médica/tendências , Reumatologistas/história , Reumatologistas/tendências
15.
Arthritis Care Res (Hoboken) ; 73(11): 1597-1605, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-32702188

RESUMO

OBJECTIVE: Glucocorticoids are recommended for short-term use in rheumatoid arthritis (RA), but many patients continue receiving long-term therapy. We evaluated the variability in glucocorticoid prescribing across rheumatologists to inform interventions to limit long-term glucocorticoid use to the lowest dose necessary. METHODS: Two cohorts were created using Medicare data from 2006 to 2015. Using cohort 1 (RA patients receiving disease-modifying antirheumatic drugs [DMARDs]), we calculated each rheumatologist's "provider preference" for glucocorticoids (frequency of use compared to other providers), using the ratio of observed to expected number of patients receiving glucocorticoids to account for case mix. In cohort 2 (RA patients receiving stable DMARD therapy), we evaluated whether provider preference for glucocorticoids could independently predict use of ≥5 mg/day of glucocorticoids 6-9 months after initiation of DMARD therapy. RESULTS: Using cohort 1 (1,272,644 yearly observations; 385,597 patients), we calculated provider preference among 6,875 rheumatologists (28,936 yearly observations). Provider preference was highly variable, with physicians at the lowest and upper quartiles prescribing glucocorticoids 33% less often to 31% more often (25th and 75th percentiles, respectively) than expected. In cohort 2 (155,539 patients receiving stable DMARD therapy), provider preference was strongly associated with glucocorticoid use ≥5 mg/day at 6-9 months, with a predicted probability of use of 22% (95% confidence interval [95% CI] 21.7-22.7) versus 11% (95% CI 10.2-10.9) for a patient seeing a provider in the highest versus lowest quintile of preference. CONCLUSION: Glucocorticoid prescribing for RA varies greatly among rheumatologists, and provider preference is one of the strongest predictors of a patient's long-term glucocorticoid use. These findings raise quality of care concerns and highlight the need for stronger evidence to guide RA treatment.


Assuntos
Antirreumáticos/administração & dosagem , Artrite Reumatoide/tratamento farmacológico , Atitude do Pessoal de Saúde , Glucocorticoides/administração & dosagem , Conhecimentos, Atitudes e Prática em Saúde , Padrões de Prática Médica/tendências , Reumatologistas/tendências , Idoso , Idoso de 80 Anos ou mais , Antirreumáticos/efeitos adversos , Esquema de Medicação , Prescrições de Medicamentos , Uso de Medicamentos/tendências , Feminino , Glucocorticoides/efeitos adversos , Disparidades em Assistência à Saúde/tendências , Humanos , Masculino , Medicare , Estudos Retrospectivos , Fatores de Tempo , Estados Unidos
16.
Arthritis Care Res (Hoboken) ; 73(2): 199-206, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-32475025

RESUMO

OBJECTIVE: To estimate the prevalence of rheumatoid arthritis (RA) in Puerto Rico, to describe disease-modifying antirheumatic drug (DMARD) dispensing patterns by prescriber specialty, and to illustrate the impact of RA case definition on the estimated prevalence. METHODS: This study estimated the prevalence of RA in Puerto Rico during 2016 among Medicaid and Medicaid-Medicare dually eligible beneficiaries of the Mi Salud health care plan, a federally funded health insurance program. DMARD dispensing and cost patterns were described and stratified by provider specialty. A sensitivity analysis was conducted to evaluate the effect of RA case definition on estimated prevalence. RESULTS: The prevalence of RA in 2016 was estimated to be 2 cases per 1,000 beneficiaries, with 3 per 1,000 beneficiaries among females, 4.5 times that of males. In total, 44% of beneficiaries received conventional synthetic DMARDs (csDMARDs) only, 32% received biologic or targeted synthetic DMARDs (b/tsDMARDs) only, and 24% received a combination of csDMARDs and b/tsDMARDs. Rheumatologists and a combination of specialties accounted for the highest median number of dispensed DMARDs, with 14 each. A sensitivity analysis revealed that when RA cases with ≥3 medical claims were restricted to having ≥1 DMARD claim, the estimated prevalence changed from 6 to 3 cases per 1,000 beneficiaries. CONCLUSION: The prevalence of RA in Puerto Rico in this study is lower than reported in the mainland US, possibly due to more stringent criteria to define RA. DMARD dispensing and cost patterns are similar to those found in other studies. Claims algorithms that identify RA have higher validity when pharmacy data is included.


Assuntos
Antirreumáticos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Artrite Reumatoide/epidemiologia , Benefícios do Seguro , Medicaid , Medicare , Padrões de Prática Médica/tendências , Adulto , Idoso , Idoso de 80 Anos ou mais , Antirreumáticos/economia , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/economia , Estudos Transversais , Custos de Medicamentos , Prescrições de Medicamentos , Uso de Medicamentos/tendências , Definição da Elegibilidade , Feminino , Humanos , Masculino , Medicaid/economia , Medicare/economia , Pessoa de Meia-Idade , Padrões de Prática Médica/economia , Prevalência , Porto Rico/epidemiologia , Reumatologistas/tendências , Especialização/tendências , Estados Unidos/epidemiologia , Adulto Jovem
17.
Curr Rheumatol Rev ; 17(2): 141-152, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33121412

RESUMO

The new coronavirus infection (Covid-19) is a pandemic that has affected the whole world and progresses with high morbidity and mortality. It has a high contagion rate and a course capable of rapid lung involvement with severe acute respiratory distress syndrome (ARDS) and pulmonary insufficiency. A severe clinical picture develops as a result of a "perfect cytokine storm" which results from possible immunological mechanisms triggered by the viral infection. Immune system dysregulation and possible autoinflammatory and autoimmune mechanisms are responsible for a higher amount of cytokines release from immune cells. Although no clear treatment of Covid-19 infection has emerged yet, it is argued that some disease-modifying anti-rheumatic drugs (DMARDs) may be effective in addition to anti-viral treatments. These drugs (anti-malarial drugs, colchicum dispert, biologics) have been well known to rheumatologists for years because they are used in the treatment of many inflammatory rheumatologic diseases. Another important issue is whether DMARDs, which can cause severe immunosuppression, pose a risk for Covid-19 infection and whether they have been discontinued beforehand. Although there are insufficient data on this subject, considering the risk of disease reactivation, patients may continue their DMARDs treatment under the supervision of a rheumatologist. In this article, the possible immunological mechanisms in the pathogenesis of Covid-19 infection and the efficacy and safety of various DMARDs used in the treatment are discussed from a rheumatologist's perspective in the light of recent literature data.


Assuntos
Antirreumáticos/administração & dosagem , Tratamento Farmacológico da COVID-19 , COVID-19/epidemiologia , Síndrome da Liberação de Citocina/tratamento farmacológico , Síndrome da Liberação de Citocina/epidemiologia , Reumatologistas/tendências , Corticosteroides/administração & dosagem , Corticosteroides/imunologia , Antimaláricos/administração & dosagem , Antimaláricos/imunologia , Antirreumáticos/imunologia , COVID-19/imunologia , Síndrome da Liberação de Citocina/imunologia , Humanos , SARS-CoV-2/efeitos dos fármacos , SARS-CoV-2/imunologia
18.
Clin Rheumatol ; 39(3): 643-650, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31444651

RESUMO

Pediatric rheumatology faces workforce shortages in both developed and developing regions of the world resulting in suboptimal care of children with chronic rheumatic diseases. In addition to outlining the structure of formal rheumatology training programs in North America and Europe, we attempt to summarize various strategies being implemented with success in several parts of the world to help close the gap via innovative learning strategies. We discuss the important role of professional organizations in leading this effort.


Assuntos
Educação Médica/métodos , Pediatras/provisão & distribuição , Reumatologistas/provisão & distribuição , Reumatologia/educação , Mão de Obra em Saúde , Humanos , Internacionalidade , Pediatras/tendências , Doenças Reumáticas/diagnóstico , Doenças Reumáticas/terapia , Reumatologistas/tendências , Reumatologia/tendências , Tecnologia
19.
Arthritis Care Res (Hoboken) ; 70(4): 617-626, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29400009

RESUMO

OBJECTIVE: To describe the character and composition of the 2015 US adult rheumatology workforce, evaluate workforce trends, and project supply and demand for clinical rheumatology care for 2015-2030. METHODS: The 2015 Workforce Study of Rheumatology Specialists in the US used primary and secondary data sources to estimate the baseline adult rheumatology workforce and determine demographic and geographic factors relevant to workforce modeling. Supply and demand was projected through 2030, utilizing data-driven estimations regarding the proportion and clinical full-time equivalent (FTE) of academic versus nonacademic practitioners. RESULTS: The 2015 adult workforce (physicians, nurse practitioners, and physician assistants) was estimated to be 6,013 providers (5,415 clinical FTE). At baseline, the estimated demand exceeded the supply of clinical FTE by 700 (12.9%). By 2030, the supply of rheumatology clinical providers is projected to fall to 4,882 providers, or 4,051 clinical FTE (a 25.2% decrease in supply from 2015 baseline levels). Demand in 2030 is projected to exceed supply by 4,133 clinical FTE (102%). CONCLUSION: The adult rheumatology workforce projections reflect a major demographic and geographic shift that will significantly impact the supply of the future workforce by 2030. These shifts include baby-boomer retirements, a millennial predominance, and an increase of female and part-time providers, in parallel with an increased demand for adult rheumatology care due to the growing and aging US population. Regional and innovative strategies will be necessary to manage access to care and reduce barriers to care for rheumatology patients.


Assuntos
Prestação Integrada de Cuidados de Saúde/tendências , Necessidades e Demandas de Serviços de Saúde/tendências , Mão de Obra em Saúde/tendências , Avaliação das Necessidades/tendências , Reumatologistas/tendências , Reumatologia/tendências , Idoso , Área Programática de Saúde , Feminino , Previsões , Humanos , Masculino , Pessoa de Meia-Idade , Admissão e Escalonamento de Pessoal/tendências , Reumatologistas/provisão & distribuição , Fatores de Tempo , Estados Unidos
20.
Arthritis Care Res (Hoboken) ; 70(2): 268-274, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-28464558

RESUMO

OBJECTIVE: To compare practice patterns and prescribing differences for juvenile idiopathic arthritis (JIA) between adult rheumatologists (ARs) and pediatric rheumatologists (PRs), the perceived educational needs, and factors that enhance or impede co-management. METHODS: Two parallel, cross-sectional surveys focusing on JIA were administered in 2009 to a random sample of 193 PRs and 500 ARs using the American College of Rheumatology membership file. Bivariate analysis was conducted for common items. RESULTS: The response rate was 62.1% for ARs (n = 306) and 72.3% for PRs (n = 138). Only 23% of responding ARs (n = 69) reported caring for children with JIA. Of these, 94% strongly agreed/agreed feeling comfortable diagnosing JIA; however, only 76% felt comfortable treating JIA. Clinical vignettes highlighted several prescribing differences. Forty-eight percent of ARs and 31% of PRs felt medications to treat JIA did not have clear dosing guidelines. Though PRs initiated disease-modifying antirheumatic drugs and biologic agents earlier, treatments were similar after 3 months. To enhance co-management, 74% of pediatric respondents endorsed shared medical records. CONCLUSION: Nearly one-quarter of surveyed ARs care for children with JIA, with most limiting their practice to older children. There was more discomfort in treating JIA than diagnosing it, and there were significant prescribing differences. Both provider types identified the need for better dosing and treatment resources. Updated management guidelines along with exposure to pediatric rheumatology in fellowship could reduce treatment differences and enhance the care of children with JIA. Shared medical records and improvement in reimbursement may optimize co-management.


Assuntos
Antirreumáticos/uso terapêutico , Artrite Juvenil/tratamento farmacológico , Padrões de Prática Médica/tendências , Reumatologistas/tendências , Adolescente , Adulto , Fatores Etários , Antirreumáticos/efeitos adversos , Artrite Juvenil/diagnóstico , Atitude do Pessoal de Saúde , Criança , Pré-Escolar , Competência Clínica , Estudos Transversais , Cálculos da Dosagem de Medicamento , Prescrições de Medicamentos , Pesquisas sobre Atenção à Saúde , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Reumatologistas/psicologia , Fatores de Risco
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