Synthesis and functional characterization of tridegin and its analogues: inhibitors and substrates of factor XIIIa.
Böhm, Miriam; Kühl, Toni; Hardes, Kornelia; Coch, Richard; Arkona, Christoph; Schlott, Bernhard; Steinmetzer, Torsten; Imhof, Diana.
; 7(2): 326-33, 2012 Feb 06.
Artigo em Inglês | MEDLINE | ID: mdl-22162181
Hemmstoffe von Faktor XIIIa.
Novel insights into structure and function of factor XIIIa-inhibitor tridegin.
Synthesis and characterization of novel fluorogenic substrates of coagulation factor XIII-A.
Identification of amino acid residues that are crucial for FXIII-A intersubunit interactions and stability.
Coagulation factor XIII serves as protein disulfide isomerase.
Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile.
Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries.
Mass spectrometry-based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots.
Factor XIIIa generation assay: a tool for studying factor XIII function in plasma.
Comparison of F13A1 gene mutations in 73 patients treated with recombinant FXIII-A<sub>2</sub>.