Novel insights into structure and function of factor XIIIa-inhibitor tridegin.
Böhm, Miriam; Bäuml, Charlotte A; Hardes, Kornelia; Steinmetzer, Torsten; Roeser, Dirk; Schaub, Yvonne; Than, Manuel E; Biswas, Arijit; Imhof, Diana.
J Med Chem
; 57(24): 10355-65, 2014 Dec 26.
Artigo em Inglês | MEDLINE | ID: mdl-25415134
Identification of amino acid residues that are crucial for FXIII-A intersubunit interactions and stability.
Hemmstoffe von Faktor XIIIa.
Mass spectrometry-based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots.
Synthesis and functional characterization of tridegin and its analogues: inhibitors and substrates of factor XIIIa.
Ozone-induced oxidative modification of plasma fibrin-stabilizing factor.
Synthesis and characterization of novel fluorogenic substrates of coagulation factor XIII-A.
Interaction of factor XIII subunits.
Comparison of F13A1 gene mutations in 73 patients treated with recombinant FXIII-A<sub>2</sub>.
Proteosomal degradation of naturally recurring R260C missense and exon-IV deletion mutants of factor XIII A-subunit expressed in mammalian cells.
Factor XIIIa generation assay: a tool for studying factor XIII function in plasma.