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Estudio comparativo de equipos INR capilar "point of care" versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K / Comparison of point of care capillary international normalized ratio (INR) with INR measured in venous samples

Roco, Ángela; Nieto, Elena; Quintana, Marianela; Muñoz, Jessica; Ortíz, Víctor; Moreno, Marcelo; Mejías, Fanny; Godoy, Gerald; Zambrano, Johana; Bruna, Stephanie; Bravo, Gabriela; Cabrera, Claudia; Salas, Patricio; Moena, Valeria; Leal, Bryan; Suárez, Marcelo; Quiñones, Luis A.
Rev. méd. Chile ; 147(10): 1273-1282, oct. 2019. tab, graf
Artigo em Espanhol | LILACS | ID: biblio-1058594
Background: INR is used to monitor the treatment with vitamin K antagonists. A strategy to reduce waiting times for sampling is to measure INR in a capillary sample using a portable point of care (POC) type coagulometer. Aim: To evaluate the correlation of CoaguChek Pro II™, Xprecia™ and microINR™ with venous INR measured at the clinical laboratory and their ease of use. Materials and Methods: Patients provided capillary and venous blood samples for parallel tests comparing Xprecia™ Stride with CoaguChek Pro II™ and with venous INR, microINR™ with CoaguChek Pro IITM and with venous INR. The devices' ease of use was assessed surveying the sampling staff. Results: The three tested devices had good correlation coefficients with venous INR: CoaguChek Pro IITM 0.953 and 0.962; Xprecia™ of 0.912 and microINR™ of 0.932. The correlation coefficient of Xprecia™ with CoaguChek Pro IITM was 0.937 and microINR™ with CoaguChek Pro IITM was 0.976. Conclusions: CoaguChek Pro IITM, Xprecia™ and microINR™ results had a good correlation coefficient with INR measured at the laboratory. Our results indicate that, in the hands of trained users, POC-type coagulometers are reliable and acceptable for routine use in anticoagulant treatment control.
Biblioteca responsável: CL1.1