AIDS-related progressive multifocal leukoencephalopathy
Abrão, Carolina de Oliveira; Silva, Lissa Rodrigues Machado da; Souza, Luiz Carlos Silva; Bisso, Nathalia de Mello; Turchi, Marília Dalva; Guilarde, Adriana Oliveira.
Rev. Soc. Bras. Med. Trop
; 54: e02522020, 2021. tab
Artigo
em Inglês
| SES-SP, Coleciona SUS, LILACS | ID: biblio-1143893
Abstract
INTRODUCTION:
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).METHODS:
We described the profile of laboratory-confirmed PML cases among AIDS patients.RESULTS:
A total of 43 HIV patients with clinical conditions compatible with PML were obtained; 5 cases were confirmed by JCV testing. The main clinical finding was mental confusion. Median CD4 count was 54 cells/mm³.CONCLUSIONS:
Three of the five confirmed PML cases died; the time between diagnosis and death was 2, 5, and 6 months. It is important to consider JCV infection as a differential diagnosis.
Biblioteca responsável:
BR1.1
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