Early onset neonatal sepsis: diagnostic value of some laboratory tests / Sepsis neonatal de inicio temprano: valor diagnóstico de algunas pruebas de laboratorio
Licona Rivera, Tania Soledad; Fajardo Dubon, German Edgardo; Ferrera García, Rubén Arturo; Mazariegos, Alejandra.
Int. j. med. surg. sci. (Print)
; 4(1): 1109-1114, mar. 2017. tab, graf
Artigo
em Inglês
| LILACS | ID: biblio-1284321
Early Onset Neonatal Sepsis (EONS) is a clinical situation resulting from the invasion andproliferation of bacteria, fungi or viruses in the newborn (NB) bloodstream, which occurs within the first 72hours of life. To determine the diagnostic usefulness of laboratory tests performed on infants with suspicion ofearly neonatal sepsis at the Santa Barbara Integrated Hospital, Honduras. A case-control study was carried outduring 2016; the cases were 20 infants with early onset neonatal sepsis, and the controls were 40 infants whowere admitted as potentially septic, but the blood culture result was negative. Sensitivity, specificity, positivepredictive value (PPV) and negative (NPV) of leukocytosis, platelets, initial C-reactive protein (CRP) and controlwere calculated. Data were analyzed with SPSS version 19. It was found that 17 (28.3 %) NB were women and43 (71.7 %) were men. The VPP of the initial PCR was 5 %, increasing to 85 % in the control study. The isolatedmicroorganism was enterobacter in 6 (30 %) of the RNs. Of the 23 (38.3 %) neonates who presentedcomplications; 11 (48 %) had positive blood culture and 12 (52 %) had negative blood cultures. The dischargecondition was medical discharge in 55 (92 %) and referred to a more complex hospital 5 (8 %) of the neonates.The VPP of the C-reactive protein increases considerably when doing a laboratory control,between 24-48 hours.
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CL61.1
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