Herpes simplex virus-1 triggered hemophagocytic lymphohistiocytosis in a patient with granulomatosis with polyangiitis
Autops. Case Rep
; 12: e2021395, 2022. graf
Article
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LILACS-Express
| LILACS
| ID: biblio-1393985
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a rare, aggressive hyperinflammatory syndrome in which an inciting event triggers massive, uninhibited activation of T lymphocytes and macrophages. Although viral infections are the most common trigger of HLH, cases of HSV-1 induced HLH are rare in adults. We present the case and postmortem findings of a 27-year-old woman diagnosed with HLH in the setting of immunosuppression for the treatment of granulomatosis with polyangiitis (GPA). Autopsy revealed evidence of herpes simplex virus-1 (HSV-1) infection and no findings suggestive of GPA recurrence.
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1
Coleções:
01-internacional
Base de dados:
LILACS
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article