Surveillance of Shiga toxin-producing Escherichia coli associated bloody diarrhea in Argentina / Vigilancia de diarrea sanguinolenta asociada a Escherichia coli productor de toxina Shiga en Argentina
Rivas, Marta; Pichel, Mariana; Colonna, Mariana; López Casanello, Adrián; Alconcherc, Laura F.; Galavottic, Jimena; Principid, Iliana; Pérez Araujo, Sofía; Ramíreze, Flavia B.; Gonzáleze, Gladys; Pianciola, Luis A.; Mazzeo, Melina; Suarez, Ángela; Oderiz, Sebastián; Ghezzi, Lidia F.R.; Arrigo, Diego J.; Paladiné, José H.; Baroni, María R.; Pérez, Susana; Tamborini, Ana.
Rev. argent. microbiol
; 55(4): 2-2, Dec. 2023.
Artigo
em Inglês
|
LILACS-Express
| ID: biblio-1550709
Abstract In Argentina, hemolytic uremic syndrome (HUS) caused by Shiga toxin-producing Escherichia coli (STEC-HUS) infection is endemic, and reliable data about prevalence and risk factors have been available since 2000. However, information about STEC-associated bloody diarrhea (BD) is limited. A prospective study was performed during the period October Surveillance; 2018-June 2019 in seven tertiary-hospitals and 18 referral units from different regions, aiming of STEC-HUS cases in the same hospitals and during the same period were also assessed. Twenty-nine (4.1%) of the BD patients were STEC-positive, as determined by the Shiga Toxin Quik Chek (STQC) test and/or the multiplex polymerase chain reaction (mPCR) assay. The highest fre-quencies were found in the Southern region (Neuquén, 8.7%; Bahía Blanca, 7.9%), in children between 12 and 23 month of age (8.8%), during summertime. Four (13.8%) cases progressed to HUS, three to nine days after diarrhea onset. Twenty-seven STEC-HUS in children under 5 years of age (77.8%) were enrolled, 51.9% were female; 44% were Stx-positive by STQC and all by mPCR. The most common serotypes were O157H7 and O145H28 and the prevalent geno-types, both among BD and HUS cases, were sfx2a-only or -associated. Considering the endemic behavior of HUS and its high incidence, these data show that the rate of STEC-positive cases is low among BD patients. However, the early recognition of STEC-positive cases is important for patient monitoring and initiation of supportive treatment.
Biblioteca responsável:
AR1.1
Texto completo
Documentos relacionados