Abstract The objective of this study was to integrate findings related to
Zika virus from the scientific
literature. An integrative
review of
Medline was conducted, and data search was performed using the
Health Sciences Descriptor Zika virus and the following
filters full texts available; studies in
humans; full articles; and
publications in Portuguese, French, English, and Spanish. After application of the
filters, followed by
reading of the titles, abstracts, and full texts, 44 studies were included in the
review, for which content
analysis was performed. A large part of the
literature comprised
review articles (84%; N=37); the majority was in English (95%, N=42). In 2016, 84% (N=37) of our sample articles was published, while in 2017, 16% (N=7) was published. The main form of viral
transmission was thorough the
mosquito Aedes aegypti (N=30). In addition, sexual
transmission (N=09),
transmission through
blood transfusion (N=16), vertical
transmission (N=21) and
transmission from occupational activities (N=03) occurred. It was possible to
diagnose the
disease by testing
blood (N=22),
urine (N=14),
saliva (N=06),
semen/
sperm (N=03), cerebrospinal and
amniotic fluid, and other
tissues (N=02). Symptomatology occurred in 1-5 people (N=10) between 3 and 7 days after a
mosquito bite (N=09).
Complications observed were
Guillain Barré syndrome (N=27); neurological Zika
syndrome (N=27);
meningitis,
meningoencephalitis, and
myelitis (N=07); deaths and/or
newborns (N=03). The
review provides scientific evidence that contributes to the care,
planning and implementation of
public policies.