Caracterización clínica de los casos de enfermedad meningocóccica por serogrupo W135 confirmados durante el año 2012 en Chile / Clinical characterization of cases with meningococcal disease by W135 group in Chile, 2012
Moreno, Gabriela; López, Darío; Vergara, Natalia; Gallegos, Doris; Advis, María F; Loayza, Sergio.
Rev. chil. infectol
; 30(4): 346-349, ago. 2013. graf, tab
Artigo
em Espanhol
| LILACS | ID: lil-690523
Background:
During 2012 in Chile, there were 60 cases of serogroup W135 meningococcal disease, which accounts for 57.7% of identified serogroup cases.Aim:
To describe main clinical features of patients with serogroup W135 meningococcal disease confirmed in 2012. Material andMethods:
Descriptive study of case series based on retrospective review of medical records.Results:
Male patients represented 61.7% and 46.7% were children under 5 years. At first clinical attention, 3.4% of patients were suspected of meningococcal disease, while 83.3% had meningococcemia as final diagnosis. Also at first attention, the most common symptoms or clinical signs were fever ≥ 38.0° C (60.3%), cold symptoms (52.5%), and nausea or vomiting (46.7%). Meningeal signs had a low frequency (8.7%). Diarrhea was the second most common symptom found among deceased patients (55.6%) and statistically higher than survivors (26.8%; p = 0.034). Six cases reported with sequelae limb amputation, hearing loss or neurological damage, and mortality was 31.7%.Discussion:
In 2012, serogroup W135 meningococcal disease reported high mortality, atypical clinical presentation, low initial meningococcal disease diagnosis, and a high number of cases with poor clinical course.
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