Epidemiology and control of vancomycin-resistant enterococci in a regional neonatal intensive care unit.
Pediatr Infect Dis J
; 18(4): 352-6, 1999 Apr.
Article
em En
| MEDLINE
| ID: mdl-10223689
ABSTRACT
BACKGROUND:
After the occurrence of two cases of bloodstream infection with vancomycin-resistant enterococci (VRE) in our regional neonatal intensive care unit, we studied the epidemiology of VRE and applied extensive infection control measures to the unit to control VRE transmission.METHODS:
Infection control measures applied to the unit included weekly surveillance for VRE colonization; education; cohorting of VRE-positive, VRE-negative and VRE-exposed babies with separate personnel and equipment for each group; use of gowns and gloves on room entry; and hand washing before and after each patient contact. Risk factors for VRE colonization were determined with a stepwise logistic regression model.RESULTS:
Thirty-three (40.2%) babies became colonized with VRE. The VRE colonization rate was reduced from 67% to 7% after implementation of infection control measures. Prolonged antimicrobial treatment and low birth weight were significantly associated with an increased risk of VRE colonization.CONCLUSION:
VRE can spread rapidly among newborns in a regional neonatal intensive care unit. Strict infection control measures can reduce the rate of VRE colonization among neonates.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vancomicina
/
Infecção Hospitalar
/
Infecções por Bactérias Gram-Positivas
/
Enterococcus
/
Antibacterianos
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Humans
/
Newborn
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article