Central pain after pontine infarction is associated with changes in opioid receptor binding: a PET study with 11C-diprenorphine.
AJNR Am J Neuroradiol
; 20(4): 686-90, 1999 Apr.
Article
em En
| MEDLINE
| ID: mdl-10319982
ABSTRACT
Using 18F-fluorodeoxyglucose and 11C-diprenorphine positron emission tomography (PET), we investigated alterations in glucose metabolism and opioid receptor binding in a patient with central poststroke pain, which developed after a small pontine hemorrhagic infarction. In comparison with normal databases, reduced 11C-diprenorphine binding was more accentuated than the hypometabolism on the lateral cortical surface contralateral to the symptoms, and a differential abnormal distribution between the tracers was seen in pain-related central structures. These results show that 11C-diprenorphine PET provides unique information for the understanding of central poststroke pain.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dor
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Ponte
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Radioisótopos de Carbono
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Tomografia Computadorizada de Emissão
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Infarto Cerebral
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Transtornos de Sensação
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Receptores Opioides
/
Compostos Radiofarmacêuticos
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Diprenorfina
/
Antagonistas de Entorpecentes
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
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Aged
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article