Engineering the mouse genome by site-specific recombination.
Curr Opin Biotechnol
; 10(5): 470-6, 1999 Oct.
Article
em En
| MEDLINE
| ID: mdl-10508631
Site-specific recombination systems are powerful tools for introducing predetermined modifications into eukaryotic genomes. Recent advances allow the manipulation of chromosomal DNA in a spatially and temporally controlled manner in mice, offering unprecedented possibilities for studying mammalian genome function and for generating animal models for human diseases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recombinação Genética
/
Proteínas Virais
/
Camundongos Transgênicos
/
Mutagênese Sítio-Dirigida
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Genoma
Limite:
Animals
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article