[Neutralizing antibodies in patients with multiple sclerosis treated with interferon beta-1b]. / Anticuerpos neutralizantes en pacientes con esclerosis múltiple tratados con interferón beta-1b.
Med Clin (Barc)
; 114(5): 169-70, 2000 Feb 12.
Article
em Es
| MEDLINE
| ID: mdl-10738721
ABSTRACT
BACKGROUND:
Neutralising antibodies (NABs) against interferon beta have been described in one third of patients with multiple sclerosis treated with interferon beta. We have analysed the frequency of NABs and their clinical consequences. PATIENTS ANDMETHODS:
We have studied 68 patients. NABs were determined by protein A Myxovirus assay.RESULTS:
Positive NABs were detected in 13% of the patients after 2 years of treatment.CONCLUSIONS:
It does not seem to exist a relationship between presence of NABs and a poor evolution of the disease in our patients with multiple sclerosis treated with beta interferon.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adjuvantes Imunológicos
/
Interferon beta
/
Esclerose Múltipla
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Male
Idioma:
Es
Ano de publicação:
2000
Tipo de documento:
Article