Hemolytic uremic syndrome in a child with leukemia and cytomegalovirus infection.
Pediatr Nephrol
; 14(12): 1118-20, 2000 Oct.
Article
em En
| MEDLINE
| ID: mdl-11045399
ABSTRACT
A 2-year-old boy had a severe cytomegalovirus (CMV) infection with multi-organ involvement, while on maintenance therapy for acute lymphoblastic leukemia. The patient was treated with intravenous gancyclovir, with a marked improvement in his clinical status, with the exception of a progressive deterioration of the renal function. He also developed hemolytic anemia and thrombocytopenia, suggesting a diagnosis of atypical hemolytic uremic syndrome (HUS). A percutaneous renal biopsy showed lesions consistent with HUS, but no evidence of CMV infection. The patient had a good clinical outcome with no evidence of renal sequelae. We report a rare association of CMV infection and HUS in the pediatric age-group, which suggests a possible cause-effect relationship that deserves further evaluation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Citomegalovirus
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Síndrome Hemolítico-Urêmica
Limite:
Child, preschool
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article