Y chromosome sequence variation and the history of human populations.
Nat Genet
; 26(3): 358-61, 2000 Nov.
Article
em En
| MEDLINE
| ID: mdl-11062480
ABSTRACT
Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting inference of human evolution, population affinity and demographic history. We used denaturing high-performance liquid chromatography (DHPLC; ref. 2) to identify 160 of the 166 bi-allelic and 1 tri-allelic site that formed a parsimonious genealogy of 116 haplotypes, several of which display distinct population affinities based on the analysis of 1062 globally representative individuals. A minority of contemporary East Africans and Khoisan represent the descendants of the most ancestral patrilineages of anatomically modern humans that left Africa between 35,000 and 89,000 years ago.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Filogenia
/
Cromossomo Y
/
Hominidae
/
Etnicidade
/
Evolução Molecular
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
/
Male
País/Região como assunto:
Africa
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article