Kidney cadmium as compared to other markers of cadmium exposure in workers at a secondary metal smelter.
Am J Ind Med
; 39(1): 19-28, 2001 Jan.
Article
em En
| MEDLINE
| ID: mdl-11148012
ABSTRACT
BACKGROUND:
The aim of the study was to evaluate whether cadmium concentrations in kidney (K-Cd), blood (B-Cd) or urine (U-Cd) could reveal previous occupational cadmium exposure at a metal smelter.METHODS:
The study included 90 smelters and 35 controls (B-Cd and U-Cd determination). In a subgroup (N = 33), K-Cd was also determined.RESULTS:
B-Cd (median 4.6; range 0.5-53 nmol/L), U-Cd (0. 29; 0.04-1.9 micromol/mol creatinine) and K-Cd (14; 3-61 microg/g wet weight) were similar to reported concentrations in the general Swedish population. In the subgroup, significant associations (P<0. 001) were obtained between B-Cd and K-Cd (r = 0.70), U-Cd and K-Cd (r = 0.60) and between U-Cd and B-Cd (r = 0.62). Multiple regression analyses revealed smoking as the major predictor of K-Cd, B-Cd, and U-Cd. B-Cd and U-Cd were both associated with the duration of employment at the smelter.CONCLUSIONS:
There was no statistically significant evidence of previous occupational exposure at the smelter from measurement of K-Cd.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cádmio
/
Exposição Ocupacional
/
Rim
/
Metalurgia
Tipo de estudo:
Prognostic_studies
Limite:
Adult
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Aged
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Humans
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Male
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Middle aged
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article