In vitro metabolism of 1-phenyl-2-(n-propylamino) propane (N-propylamphetamine) by rat liver homogenates.
J Pharm Pharmacol
; 28(11): 815-21, 1976 Nov.
Article
em En
| MEDLINE
| ID: mdl-11289
ABSTRACT
In vitro incubation of (+/-)-N-(n-propyl)amphetamine (NPA) with the 12000 g supernatant fraction of rat liver hmogenate resulted in the formation of two N-oxygenated products identified as N-hydroxy-1-phenyl-2(n-propylamino)propane and N-[(1-methyl-2-phenyl) ethyl]-1-propanamine N-oxide by g.l.c., g.l.c.-m.s. and t.l.c. Amphetamine, phenylacetone,...
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microssomos Hepáticos
/
Anfetaminas
/
Fígado
Limite:
Animals
Idioma:
En
Ano de publicação:
1976
Tipo de documento:
Article