Quasistatic zooming of FDTD E-field computations: the impact of down-scaling techniques.
Phys Med Biol
; 46(5): 1539-51, 2001 May.
Article
em En
| MEDLINE
| ID: mdl-11384069
ABSTRACT
Due to current computer limitations, regional hyperthermia treatment planning (HTP) is practically limited to a resolution of 1 cm, whereas a millimetre resolution is desired. Using the centimetre resolution E-field distribution, computed with, for example, the finite-difference time-domain (FDTD) method and the millimetre resolution patient anatomy it is possible to obtain a millimetre resolution SAR distribution in a volume of interest (VOI) by means of quasistatic zooming. To compute the required low-resolution E-field distribution, a low-resolution dielectric geometry is needed which is constructed by down-scaling the millimetre resolution dielectric geometry. In this study we have investigated which down-scaling technique results in a dielectric geometry that yields the best low-resolution E-field distribution as input for quasistatic zooming. A segmented 2 mm resolution CT data set of a patient has been down-scaled to 1 cm resolution using three different techniques 'winner-takes-all', 'volumetric averaging' and 'anisotropic volumetric averaging'. The E-field distributions computed for those low-resolution dielectric geometries have been used as input for quasistatic zooming. The resulting zoomed-resolution SAR distributions were compared with a reference the 2 mm resolution SAR distribution computed with the FDTD method. The E-field distribution for both a simple phantom and the complex partial patient geometry down-scaled using 'anisotropic volumetric averaging' resulted in zoomed-resolution SAR distributions that best approximate the corresponding high-resolution SAR distribution (correlation 97, 96% and absolute averaged difference 6, 14% respectively).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Terapia Assistida por Computador
/
Imagens de Fantasmas
/
Hipertermia Induzida
Limite:
Humans
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article