[Selective bladder sparing with transrectal resection of muscle-infiltrating tumors]. / Preservación vesical selectiva mediante resección transuretral de los tumores músculo-infiltrantes.
Actas Urol Esp
; 25(4): 264-8, 2001 Apr.
Article
em Es
| MEDLINE
| ID: mdl-11455827
ABSTRACT
OBJECTIVE:
To disclose te ability of TUR as monotherapy in muscle invasive bladder cancer. MATERIAL ANDMETHODS:
27 patients with muscle-invasive bladder cancer recruited throughout 1991-1999 were allocated into a protocol based on TUR. 30-45 days after the first TUR a second procedure was performed. The number of recurrences and progressions was registered. Progression-free survival and survival were analyzed using Kaplan-Meier estimates.RESULTS:
Two patients were excluded due to persistence of muscle-invasive disease after the second resection. 8 subjects (32%) were lost in follow-up. 17 were eventually evaluable. 12 patients (70.5%) had recurrences. Eventually, 4 more cystectomies were undertaken for invasive recurrences (4/17, 23.5%). During the study period, 3 deaths were recorder (3/17, 17.6%). The actuarial probability of progression at 93 months was estimated on 60%.CONCLUSIONS:
75% of patients retained their bladders. The proportion of patients lost in follow-up was very high. Patients must commit to a close surveillance.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Bexiga Urinária
/
Cistectomia
Tipo de estudo:
Observational_studies
Limite:
Aged
/
Humans
Idioma:
Es
Ano de publicação:
2001
Tipo de documento:
Article