The influence of different structure representations on the clustering of an RNA nucleotides data set.
J Chem Inf Comput Sci
; 41(5): 1388-94, 2001.
Article
em En
| MEDLINE
| ID: mdl-11604040
ABSTRACT
The last couple of years an overwhelming amount of data has emerged in the field of biomolecular structure determination. To explore information hidden in these structure databases, clustering techniques can be used. The outcome of the clustering experiments largely depends, among others, on the way the data is represented; therefore, the choice how to represent the molecular structure information is extremely important. This article describes what the influence of the different representations on the clustering is and how it can be analyzed by means of a dendrogram comparison method. All experiments are performed using a data set consisting of RNA trinucleotides. Besides the most basic structure representation, the Cartesian coordinates representation, several other structure representations are used.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
RNA
/
Bases de Dados de Ácidos Nucleicos
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article