Structure-activity relationships for analogues of the phenazine-based dual topoisomerase I/II inhibitor XR11576.
Bioorg Med Chem Lett
; 12(3): 415-8, 2002 Feb 11.
Article
em En
| MEDLINE
| ID: mdl-11814810
As part of a programme to identify further analogues of the dual topo I/II inhibitor XR11576, we describe here the syntheses and SAR studies of various 'minimal' and 3,4-benzofused phenazine chromophores of the phenazine template of XR11576.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenazinas
/
Inibidores da Topoisomerase I
/
Inibidores da Topoisomerase II
/
Antineoplásicos
Limite:
Humans
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article