Glutathione transferase isoenzymes from frog (Xenopus laevis) liver and embryo.
Biochim Biophys Acta
; 1569(1-3): 81-5, 2002 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-11853961
ABSTRACT
The expression of glutathione transferase isoenzymes has been investigated in embryo and adult liver of the frog Xenopus laevis. By analysing the GST isoenzymes recovered from GSH-affinity chromatography in terms of electrophoretic mobility, HPLC elution profile, immunological reactivity, N-terminal amino acid sequence and mass spectrometry molecular mass no significant difference in the GST subunit composition between embryos and liver was found. In both tissues the same three subunits, showing similarity to mu, alpha and sigma class GSTs, are present. These results, together with those previously reported for toad (Bufo bufo), strongly support the notion that the transition from an aquatic environment to a terrestrial atmosphere containing high oxygen concentration has accompanied specific GST gene expression.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Xenopus laevis
/
Embrião não Mamífero
/
Glutationa Transferase
/
Fígado
Limite:
Animals
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article