Transfusion volume in infants with very low birth weight: a randomized trial of 10 versus 20 ml/kg.
J Pediatr Hematol Oncol
; 24(1): 43-6, 2002 Jan.
Article
em En
| MEDLINE
| ID: mdl-11902739
ABSTRACT
BACKGROUND:
Although preterm infants often require transfusions of red blood cells for anemia of prematurity, the optimal volume of blood to be transfused has not been established. OBSERVATIONS Infants with birth weights between 500 and 1,500 g were randomly assigned to receive 10 or 20 mL/kg red blood cells. Infants with transfusions of 20 mL/kg had a greater hemoglobin (14.2 +/- 1.9 vs. 12.0 +/- 1.9 g/dL, P = 0. 003) and hematocrit (41.2 +/- 5.9 vs. 32.3 +/- 7.1%, P = 0.001) levels after transfusion compared with those who received transfusions of 10 mL/kg. There were no measured differences in pulmonary function in either group after transfusion.CONCLUSIONS:
Transfusion with 20 mL/kg red blood cells produces a significantly greater increase in hemoglobin and hematocrit levels than does a transfusion with 10 mL/kg, without any detrimental effects on pulmonary function.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transfusão de Eritrócitos
/
Recém-Nascido de muito Baixo Peso
Tipo de estudo:
Clinical_trials
Limite:
Humans
/
Newborn
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article