Effect of ricin on biosynthesis of myeloma protein (IgA) and general cellular proteins in MOPC-315 cells.
Biochim Biophys Acta
; 414(2): 155-60, 1975 Dec 04.
Article
em En
| MEDLINE
| ID: mdl-1191708
ABSTRACT
Ricin, a phyto-toxin from the seeds of Ricinus communis, preferentially inhibits synthesis of myeloma protein by MOPC-315 cells as compared to the synthesis of general proteins. In contrast, cycloheximide inhibited equally both myeloma protein synthesis as well as general protein synthesis. These results suggest that proteins synthesized near or on cell membranes are more sensitive to Ricin which binds to the acceptor molecule on the plasma membrane.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Plantas
/
Ricina
/
Biossíntese de Proteínas
/
Imunoglobulina A
/
Proteínas do Mieloma
/
Proteínas de Neoplasias
Idioma:
En
Ano de publicação:
1975
Tipo de documento:
Article